Abstract
A new rifampin resistance gene, arr-2, has been found in Pseudomonas aeruginosa. The ARR-2 protein shows 54% amino acid identity to the rifampin ADP-ribosylating transferase encoded by the arr gene from Mycobacterium smegmatis. This arr-2 gene is located on a gene cassette within a class I integron.
MeSH terms
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Amino Acid Sequence
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Antibiotics, Antitubercular / pharmacology
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Bacterial Proteins / genetics*
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Base Sequence
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DNA, Bacterial / analysis
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Drug Resistance, Microbial / genetics
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Humans
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Microbial Sensitivity Tests
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Molecular Sequence Data
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Mycobacterium smegmatis / genetics
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Pseudomonas aeruginosa / genetics*
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Rifampin / pharmacology
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Sequence Homology, Amino Acid
Substances
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ARR-2 protein, Bacteria
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ARR-2 protein, Pseudomonas aeruginosa
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Antibiotics, Antitubercular
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Bacterial Proteins
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DNA, Bacterial
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Rifampin