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Molecular mechanism by which pioglitazone preserves pancreatic β-cells in obese diabetic mice: evidence for acute and chronic actions as a PPARγ agonist

Yukiko Kanda, Masashi Shimoda, Sumiko Hamamoto, Kazuhito Tawaramoto, Fumiko Kawasaki, Mitsuru Hashiramoto, Koji Nakashima, Michihiro Matsuki, Kohei Kaku

Am J Physiol Endocrinol Metab. 2010 Feb; 298(2): E278–E286. Published online 2009 Nov 17. doi: 10.1152/ajpendo.00388.2009

PMCID:: PMC2822485

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