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Select item 71708631.

Loss of AKAP1 triggers Drp1 dephosphorylation-mediated mitochondrial fission and loss in retinal ganglion cells

Genea Edwards, Guy A. Perkins, Keun-Young Kim, YeEun Kong, Yonghoon Lee, Soo-Ho Choi, Yujia Liu, Dorota Skowronska-Krawczyk, Robert N. Weinreb, Linda Zangwill, Stefan Strack, Won-Kyu Ju

Cell Death Dis. 2020 Apr; 11(4): 254. Published online 2020 Apr 20. doi: 10.1038/s41419-020-2456-6

PMCID:: PMC7170863

Abstract Article PDF–8.4M

Select item 69626162.

Cardiac ischemia-reperfusion injury induces ROS-dependent loss of PKA regulatory subunit RIα

Kristofer J. Haushalter, Jan M. Schilling, Young Song, Mira Sastri, Guy A. Perkins, Stefan Strack, Susan S. Taylor, Hemal H. Patel

Am J Physiol Heart Circ Physiol. 2019 Dec 1; 317(6): H1231–H1242. Published online 2019 Nov 1. doi: 10.1152/ajpheart.00237.2019

PMCID:: PMC6962616

Abstract Article

Select item 66159943.

Neuroprotective Mitochondrial Remodeling by AKAP121/PKA protects HT22 cell from glutamate-induced oxidative stress

Jingdian Zhang, Jiachun Feng, Di Ma, Feng Wang, Yumeng Wang, Chunxiao Li, Xu Wang, Xiang Yin, Ming Zhang, Ruben K. Dagda, Ying Zhang

Mol Neurobiol. Author manuscript; available in PMC 2020 Aug 1.

Published in final edited form as: Mol Neurobiol. 2019 Aug; 56(8): 5586–5607. Published online 2019 Jan 16. doi: 10.1007/s12035-018-1464-3

PMCID:: PMC6615994

Abstract Article PDF–1.3M

Select item 66023004.

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules

Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer

J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252

PMCID:: PMC6602300

Abstract Article

Select item 61464985.

AKAP1 Protects from Cerebral Ischemic Stroke by Inhibiting Drp1-Dependent Mitochondrial Fission

Kyle H. Flippo, Aswini Gnanasekaran, Guy A. Perkins, Ahmad Ajmal, Ronald A. Merrill, Audrey S. Dickey, Susan S. Taylor, G. Stanley McKnight, Anil K. Chauhan, Yuriy M. Usachev, Stefan Strack

J Neurosci. 2018 Sep 19; 38(38): 8233–8242. doi: 10.1523/JNEUROSCI.0649-18.2018

PMCID:: PMC6146498

Abstract Article PDF–2.2M

Select item 60081286.

Akap1 genetic deletion increases the severity of hyperoxia-induced acute lung injury in mice

Venkata Ramireddy Narala, Jutaro Fukumoto, Helena Hernández-Cuervo, Sahebgowda Sidramagowda Patil, Sudarshan Krishnamurthy, Mason Breitzig, Lakshmi Galam, Ramani Soundararajan, Richard F. Lockey, Narasaiah Kolliputi

Am J Physiol Lung Cell Mol Physiol. 2018 May 1; 314(5): L860–L870. Published online 2018 Feb 1. doi: 10.1152/ajplung.00365.2017

PMCID:: PMC6008128

Abstract Article

Select item 59854547.

Loss of Akap1 Exacerbates Pressure Overload-Induced Cardiac Hypertrophy and Heart Failure

Gabriele G. Schiattarella, Nicola Boccella, Roberta Paolillo, Fabio Cattaneo, Valentina Trimarco, Anna Franzone, Stefania D’Apice, Giuseppe Giugliano, Laura Rinaldi, Domenica Borzacchiello, Alessandra Gentile, Assunta Lombardi, Antonio Feliciello, Giovanni Esposito, Cinzia Perrino

Front Physiol. 2018; 9: 558. Published online 2018 May 28. doi: 10.3389/fphys.2018.00558

PMCID:: PMC5985454

Abstract Article PDF–4.5M

Select item 55209008.

Mitochondrial AKAP1 supports mTOR pathway and tumor growth

Laura Rinaldi, Maria Sepe, Rossella Delle Donne, Kristel Conte, Antonietta Arcella, Domenica Borzacchiello, Stefano Amente, Fernanda De Vita, Monia Porpora, Corrado Garbi, Maria A Oliva, Claudio Procaccini, Deriggio Faicchia, Giuseppe Matarese, Federica Zito Marino, Gaetano Rocco, Sara Pignatiello, Renato Franco, Luigi Insabato, Barbara Majello, Antonio Feliciello

Cell Death Dis. 2017 Jun; 8(6): e2842. Published online 2017 Jun 1. doi: 10.1038/cddis.2017.241

PMCID:: PMC5520900

Abstract Article PDF–2.9M

Select item 54317989.

A-Kinase Anchoring Protein 79/150 Scaffolds Transient Receptor Potential A 1 Phosphorylation and Sensitization by Metabotropic Glutamate Receptor Activation

Allison Doyle Brackley, Ruben Gomez, Kristi A. Guerrero, Armen N. Akopian, Marc J. Glucksman, Junhui Du, Susan M. Carlton, Nathaniel A. Jeske

Sci Rep. 2017; 7: 1842. Published online 2017 May 12. doi: 10.1038/s41598-017-01999-4

PMCID:: PMC5431798

Abstract Article PDF–2.4M

Select item 513539110.

Targeted deletion of AKAP7 in dentate granule cells impairs spatial discrimination

Brian W Jones, Jennifer Deem, Thomas J Younts, Michael Weisenhaus, Christina A Sanford, Margaret C Slack, Jenesa Chin, Daniela Nachmanson, Alex McKennon, Pablo E Castillo, G Stanley McKnight

eLife. 2016; 5: e20695. Published online 2016 Dec 2. doi: 10.7554/eLife.20695

PMCID:: PMC5135391

Abstract Article PDF–4.3M

Select item 485295011.

Akap1 Deficiency Promotes Mitochondrial Aberrations and Exacerbates Cardiac Injury Following Permanent Coronary Ligation via Enhanced Mitophagy and Apoptosis

Gabriele Giacomo Schiattarella, Fabio Cattaneo, Gianluigi Pironti, Fabio Magliulo, Giuseppe Carotenuto, Marinella Pirozzi, Roman Polishchuk, Domenica Borzacchiello, Roberta Paolillo, Marco Oliveti, Nicola Boccella, Marisa Avvedimento, Maria Sepe, Assunta Lombardi, Rosa Anna Busiello, Bruno Trimarco, Giovanni Esposito, Antonio Feliciello, Cinzia Perrino

PLoS One. 2016; 11(5): e0154076. Published online 2016 May 2. doi: 10.1371/journal.pone.0154076

Correction in:: PLoS One. 2016; 11(7): e0158934.

PMCID:: PMC4852950

Abstract Article PDF–5.4M

Select item 478790312.

The ubiquitin ligase Ubr4 controls stability of podocin/MEC-2 supercomplexes

Markus M. Rinschen, Puneet Bharill, Xiongwu Wu, Priyanka Kohli, Matthäus J. Reinert, Oliver Kretz, Isabel Saez, Bernhard Schermer, Martin Höhne, Malte P. Bartram, Sriram Aravamudhan, Bernard R. Brooks, David Vilchez, Tobias B. Huber, Roman-Ulrich Müller, Marcus Krüger, Thomas Benzing

Hum Mol Genet. 2016 Apr 1; 25(7): 1328–1344. Published online 2016 Jan 19. doi: 10.1093/hmg/ddw016

PMCID:: PMC4787903

Abstract Article PDF–1.0M

Select item 425807713.

Ring finger protein20 regulates hepatic lipid metabolism through protein kinase A-dependent sterol regulatory element binding protein1c degradation

Jae Ho Lee, Gha Young Lee, Hagoon Jang, Sung Sik Choe, Seung-Hoi Koo, Jae Bum Kim

Hepatology. 2014 Sep; 60(3): 844–857. Published online 2014 Jul 28. doi: 10.1002/hep.27011

PMCID:: PMC4258077

Abstract Article PDF–1.2M

Select item 382996614.

PKC and PKA Regulate AChR Dynamics at the Neuromuscular Junction of Living Mice

Isabel Martinez-Pena y Valenzuela, Marcelo Pires-Oliveira, Mohammed Akaaboune

PLoS One. 2013; 8(11): e81311. Published online 2013 Nov 15. doi: 10.1371/journal.pone.0081311

PMCID:: PMC3829966

Abstract Article PDF–1.8M

Select item 336095515.

Fine-Tuning of Drp1/Fis1 Availability by AKAP121/Siah2 Regulates Mitochondrial Adaptation to Hypoxia

Hyungsoo Kim, Maria C. Scimia, Deepti Wilkinson, Ramon D. Trelles, Malcolm R. Wood, David Bowtell, Andrew Dillin, Mark Mercola, Ze’ev A. Ronai

Mol Cell. Author manuscript; available in PMC 2012 Nov 18.

Published in final edited form as: Mol Cell. 2011 Nov 18; 44(4): 532–544. doi: 10.1016/j.molcel.2011.08.045

PMCID:: PMC3360955

Abstract Article PDF–5.9M

Select item 317805916.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302253417.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 277884418.

A mitochondrial protein compendium elucidates complex I disease biology

David J. Pagliarini, Sarah E. Calvo, Betty Chang, Sunil A. Sheth, Scott B. Vafai, Shao-En Ong, Geoffrey A. Walford, Canny Sugiana, Avihu Boneh, William K. Chen, David E. Hill, Marc Vidal, James G. Evans, David R. Thorburn, Steven A. Carr, Vamsi K. Mootha

Cell. Author manuscript; available in PMC 2009 Nov 18.

Published in final edited form as: Cell. 2008 Jul 11; 134(1): 112–123. doi: 10.1016/j.cell.2008.06.016

PMCID:: PMC2778844

Abstract Article PDF–1.2M

Select item 275551419.

Translational regulation of lipoprotein lipase in adipocytes: depletion of cellular protein kinase Cα activates binding of the C subunit of protein kinase A to the 3′-untranslated region of the lipoprotein lipase mRNA

Resat Unal, Irina Pokrovskaya, Preeti Tripathi, Brett P. Monia, Philip A. Kern, Gouri Ranganathan

Biochem J. Author manuscript; available in PMC 2009 Oct 2.

Published in final edited form as: Biochem J. 2008 Jul 15; 413(2): 315–322. doi: 10.1042/BJ20071559

PMCID:: PMC2755514

Abstract Article PDF–530K

Select item 255627020.

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin

Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108

PMCID:: PMC2556270

Abstract Article PDF–493K

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