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Items: 1 to 20 of 82

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Fibroblast growth factor 18 stimulates the proliferation of hepatic stellate cells, thereby inducing liver fibrosis
Yuichi Tsuchiya, Takao Seki, Kenta Kobayashi, Sachiko Komazawa-Sakon, Shigeyuki Shichino, Takashi Nishina, Kyoko Fukuhara, Kenichi Ikejima, Hidenari Nagai, Yoshinori Igarashi, Satoshi Ueha, Akira Oikawa, Shinya Tsurusaki, Soh Yamazaki, Chiharu Nishiyama, Tetuo Mikami, Hideo Yagita, Ko Okumura, Taketomo Kido, Atsushi Miyajima, Kouji Matsushima, Mai Imasaka, Kimi Araki, Toru Imamura, Masaki Ohmuraya, Minoru Tanaka, Hiroyasu Nakano
Nat Commun. 2023; 14: 6304. Published online 2023 Oct 9. doi: 10.1038/s41467-023-42058-z
PMCID:
PMC10562492
AbstractArticlePDF–15M
3.
Cleavage of cFLIP restrains cell death during viral infection and tissue injury and favors tissue repair
Kristel Martinez Lagunas, Deniz Pinar Savcigil, Matea Zrilic, Carlos Carvajal Fraile, Andrew Craxton, Emily Self, Iratxe Uranga-Murillo, Diego de Miguel, Maykel Arias, Sebastian Willenborg, Michael Piekarek, Marie Christine Albert, Kalvin Nugraha, Ina Lisewski, Erika Janakova, Natalia Igual, Wulf Tonnus, Ximena Hildebrandt, Mohammed Ibrahim, Marlies Ballegeer, Xavier Saelens, Andrew Kueh, Pascal Meier, Andreas Linkermann, Julian Pardo, Sabine Eming, Henning Walczak, Marion MacFarlane, Nieves Peltzer, Alessandro Annibaldi
Sci Adv. 2023 Jul; 9(30): eadg2829. Published online 2023 Jul 26. doi: 10.1126/sciadv.adg2829
PMCID:
PMC10371024
AbstractArticlePDF–2.4M
4.
Mechanisms regulating the loss of Tregs in HUPO mice that develop spontaneous inflammatory arthritis
Qi-Quan Huang, Yiwei Hang, Renee Doyle, Qinwen Mao, Deyu Fang, Richard M. Pope
iScience. 2023 May 19; 26(5): 106734. Published online 2023 Apr 25. doi: 10.1016/j.isci.2023.106734
PMCID:
PMC10193230
AbstractArticlePDF–5.2M
5.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
6.
Bclaf1 regulates c‐FLIP expression and protects cells from TNF‐induced apoptosis and tissue injury
Rui Zhang, Teng Xue, Anwen Shao, Yue Lang, Chao Qin, Mingliang Zhao, Yu Kuang, Zhengquan Yu, Yunyun Geng, Chenyang Zhao, Jun Tang
EMBO Rep. 2022 Jan 5; 23(1): e52702. Published online 2021 Oct 25. doi: 10.15252/embr.202152702
PMCID:
PMC8728627
AbstractArticlePDF–2.2M
7.
Oncogenic signaling inhibits c-FLIPL expression and its non-apoptotic function during ECM-detachment
Matyas Abel Tsegaye, Jianping He, Kyle McGeehan, Ireland M. Murphy, Mati Nemera, Zachary T. Schafer
Sci Rep. 2021; 11: 18606. Published online 2021 Sep 20. doi: 10.1038/s41598-021-97715-4
PMCID:
PMC8452765
AbstractArticlePDF–2.2M
8.
c-FLIP regulates autophagy by interacting with Beclin-1 and influencing its stability
Luana Tomaipitinca, Simonetta Petrungaro, Pasquale D’Acunzo, Angelo Facchiano, Amit Dubey, Salvatore Rizza, Federico Giulitti, Eugenio Gaudio, Antonio Filippini, Elio Ziparo, Francesco Cecconi, Claudia Giampietri
Cell Death Dis. 2021 Jul; 12(7): 686. Published online 2021 Jul 8. doi: 10.1038/s41419-021-03957-5
PMCID:
PMC8266807
AbstractArticlePDF–2.1M
9.
Honokiol Alleviates Methionine-Choline Deficient Diet-Induced Hepatic Steatosis and Oxidative Stress in C57BL/6 Mice by Regulating CFLAR-JNK Pathway
Ting Zhai, Wei Xu, Yayun Liu, Kun Qian, Yanling Xiong, Yong Chen
Oxid Med Cell Longev. 2020; 2020: 2313641. Published online 2020 Nov 27. doi: 10.1155/2020/2313641
PMCID:
PMC7735862
AbstractArticlePDF–1.9M
10.
hnRNPK knockdown alleviates NLRP3 inflammasome priming by repressing FLIP expression in Raw264.7 macrophages
Junxia Feng, Hongyan Li, Jingchun Li, Ping Meng, Lina Wang, Chunli Liu, Shili Zhao, Wei Sun, Yunfang Zhang
Redox Rep. 2020; 25(1): 104–111. Published online 2020 Dec 3. doi: 10.1080/13510002.2020.1857157
PMCID:
PMC7717877
AbstractArticlePDF–1.2M
11.
TNF Is Partially Required for Cell-Death-Triggered Skin Inflammation upon Acute Loss of cFLIP
Maria Feoktistova, Roman Makarov, Martin Leverkus, Amir S. Yazdi, Diana Panayotova-Dimitrova
Int J Mol Sci. 2020 Nov; 21(22): 8859. Published online 2020 Nov 23. doi: 10.3390/ijms21228859
PMCID:
PMC7700656
AbstractArticlePDF–2.8M
12.
cFLIPL protects macrophages from LPS-induced pyroptosis via inhibition of complex II formation
Hayley I. Muendlein, David Jetton, Wilson M. Connolly, Keith P. Eidell, Zoie Magri, Irina Smirnova, Alexander Poltorak
Science. Author manuscript; available in PMC 2020 Jul 22.
Published in final edited form as: Science. 2020 Mar 20; 367(6484): 1379–1384. doi: 10.1126/science.aay3878
PMCID:
PMC7375259
AbstractArticlePDF–1.6M
13.
c-FLIP is crucial for IL-7/IL-15-dependent NKp46+ ILC development and protection from intestinal inflammation in mice
Ute Bank, Katrin Deiser, Carlos Plaza-Sirvent, Lisa Osbelt, Amelie Witte, Laura Knop, Rebecca Labrenz, Robert Jänsch, Felix Richter, Aindrila Biswas, Ana C. Zenclussen, Eric Vivier, Chiara Romagnani, Anja A. Kühl, Ildiko R. Dunay, Till Strowig, Ingo Schmitz, Thomas Schüler
Nat Commun. 2020; 11: 1056. Published online 2020 Feb 26. doi: 10.1038/s41467-020-14782-3
PMCID:
PMC7044440
AbstractArticlePDF–3.2M
14.
K63-linked ubiquitination regulates RIPK1 kinase activity to prevent cell death during embryogenesis and inflammation
Yong Tang, Hailin Tu, Jie Zhang, Xueqiang Zhao, Yini Wang, Jun Qin, Xin Lin
Nat Commun. 2019; 10: 4157. Published online 2019 Sep 13. doi: 10.1038/s41467-019-12033-8
PMCID:
PMC6744441
AbstractArticlePDF–7.9M
15.
FLIPL Protects Neurons against In Vivo Ischemia and In Vitro Glucose Deprivation-Induced Cell Death
Era Taoufik, Samuel Valable, Georg J. Müller, Michael L. Roberts, Didier Divoux, Antoine Tinel, Anda Voulgari-Kokota, Vivian Tseveleki, Fiorella Altruda, Hans Lassmann, Edwige Petit, Lesley Probert
J Neurosci. 2007 Jun 20; 27(25): 6633–6646. doi: 10.1523/JNEUROSCI.1091-07.2007
PMCID:
PMC6672692
AbstractArticlePDF–829K
16.
The Death Receptor Antagonist FLIP-L Interacts with Trk and Is Necessary for Neurite Outgrowth Induced by Neurotrophins
Rana S. Moubarak, Carme Solé, Marta Pascual, Humberto Gutierrez, Marta Llovera, M. José Pérez-García, Raffaella Gozzelino, Miguel F. Segura, Victoria Iglesias-Guimarais, Stéphanie Reix, Rosa M. Soler, Alun M. Davies, Eduardo Soriano, Victor J. Yuste, Joan X. Comella
J Neurosci. 2010 Apr 28; 30(17): 6094–6105. doi: 10.1523/JNEUROSCI.0537-10.2010
PMCID:
PMC6632611
AbstractArticlePDF–1.9M
17.
Control of antiviral innate immune response by protein geranylgeranylation
Shigao Yang, Alfred T. Harding, Catherine Sweeney, David Miao, Gregory Swan, Connie Zhou, Zhaozhao Jiang, Katherine A. Fitzgerald, Gianna Hammer, Martin O. Bergo, Heather K. Kroh, D. Borden Lacy, Chunxiang Sun, Michael Glogauer, Loretta G. Que, Nicholas S. Heaton, Donghai Wang
Sci Adv. 2019 May; 5(5): eaav7999. Published online 2019 May 29. doi: 10.1126/sciadv.aav7999
PMCID:
PMC6541464
AbstractArticlePDF–2.7M
18.
Necroptosis of Intestinal Epithelial Cells Induces Type 3 Innate Lymphoid Cell-Dependent Lethal Ileitis
Ryodai Shindo, Masaki Ohmuraya, Sachiko Komazawa-Sakon, Sanae Miyake, Yutaka Deguchi, Soh Yamazaki, Takashi Nishina, Takayuki Yoshimoto, Soichiro Kakuta, Masato Koike, Yasuo Uchiyama, Hiroyuki Konishi, Hiroshi Kiyama, Tetuo Mikami, Kenta Moriwaki, Kimi Araki, Hiroyasu Nakano
iScience. 2019 May 31; 15: 536–551. Published online 2019 May 14. doi: 10.1016/j.isci.2019.05.011
PMCID:
PMC6538961
AbstractArticlePDF–19M
19.
RIPK1 prevents TRADD-driven, but TNFR1 independent, apoptosis during development
Holly Anderton, Esther Bandala-Sanchez, Daniel S Simpson, James A Rickard, Ashley P Ng, Ladina Di Rago, Cathrine Hall, James E Vince, John Silke, Gianmaria Liccardi, Rebecca Feltham
Cell Death Differ. 2019 May; 26(5): 877–889. Published online 2018 Sep 5. doi: 10.1038/s41418-018-0166-8
PMCID:
PMC6461919
AbstractArticlePDF–6.5M
20.
A Dectin-1-Caspase-8 Pathway Licenses Canonical Caspase-1 Inflammasome Activation and Interleukin-1β Release in Response to a Pathogenic Fungus
Natália Ketelut-Carneiro, Sreya Ghosh, Stuart M Levitz, Katherine A Fitzgerald, João Santana da Silva
J Infect Dis. 2018 Jan 15; 217(2): 329–339. Published online 2017 Nov 1. doi: 10.1093/infdis/jix568
PMCID:
PMC6279136
AbstractArticlePDF–19M

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