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Select item 104707461.

SARS-CoV-2 hijacks p38β/MAPK11 to promote virus replication

Christina A. Higgins, Benjamin E. Nilsson-Payant, Boris Bonaventure, Andrew P. Kurland, Chengjin Ye, Tomer M. Yaron, Jared L. Johnson, Prithy Adhikary, Ilona Golynker, Maryline Panis, Oded Danziger, Brad R. Rosenberg, Lewis C. Cantley, Luis Martínez-Sobrido, Benjamin tenOever, Jeffrey R. Johnson

mBio. 2023 Jul-Aug; 14(4): e01007-23. Published online 2023 Jun 22. doi: 10.1128/mbio.01007-23

PMCID:: PMC10470746

Abstract Article PDF–4.2M

Select item 82362012.

p38β - MAPK11 and its role in female cancers

Periklis Katopodis, Rachel Kerslake, Athanasios Zikopoulos, Nefeli Beri, Vladimir Anikin

J Ovarian Res. 2021; 14: 84. Published online 2021 Jun 26. doi: 10.1186/s13048-021-00834-9

PMCID:: PMC8236201

Abstract Article PDF–2.0M

Select item 42503023.

MAPK11 in breast cancer cells enhances osteoclastogenesis and bone resorption

Zhimin He, Jin He, Zhiqiang Liu, Jingda Xu, Sofia F. Yi, Huan Liu, Jing Yang

Biochimie. Author manuscript; available in PMC 2015 Nov 1.

Published in final edited form as: Biochimie. 2014 Nov; 0: 24–32. Published online 2014 Jul 24. doi: 10.1016/j.biochi.2014.07.017

PMCID:: PMC4250302

Abstract Article PDF–1.8M

Select item 41560384.

The p38β Mitogen-activated Protein Kinase Possesses an Intrinsic Autophosphorylation Activity, Generated by a Short Region Composed of the α-G Helix and MAPK Insert

Jonah Beenstock, Sheer Ben-Yehuda, Dganit Melamed, Arie Admon, Oded Livnah, Natalie G. Ahn, David Engelberg

J Biol Chem. 2014 Aug 22; 289(34): 23546–23556. Published online 2014 Jul 8. doi: 10.1074/jbc.M114.578237

PMCID:: PMC4156038

Abstract Article PDF–3.3M

Select item 32379295.

Inhibition of SAPK2/p38 enhances sensitivity to mTORC1 inhibition by blocking IRES-mediated translation initiation in glioblastoma

Cheri Cloninger, Andrew Bernath, Tariq Bashir, Brent Holmes, Nicholas Artinian, Teresa Ruegg, Lauren Anderson, Janine Masri, Alan Lichtenstein, Joseph Gera

Mol Cancer Ther. Author manuscript; available in PMC 2012 Dec 1.

Published in final edited form as: Mol Cancer Ther. 2011 Dec; 10(12): 2244–2256. Published online 2011 Sep 12. doi: 10.1158/1535-7163.MCT-11-0478

PMCID:: PMC3237929

Abstract Article PDF–1.6M

Select item 31731336.

Phosphorylation of Raptor by p38β Participates in Arsenite-induced Mammalian Target of Rapamycin Complex 1 (mTORC1) Activation

Xiao-Nan Wu, Xue-Kun Wang, Su-Qin Wu, Jiawei Lu, Min Zheng, Yan-Hai Wang, Huamin Zhou, Hongbing Zhang, Jiahuai Han

J Biol Chem. 2011 Sep 9; 286(36): 31501–31511. Published online 2011 Jul 14. doi: 10.1074/jbc.M111.233122

PMCID:: PMC3173133

Abstract Article PDF–3.7M

Select item 30028687.

Oestrogen prevents cardiomyocyte apoptosis by suppressing p38α-mediated activation of p53 and by down-regulating p53 inhibition on p38β

Han Liu, Ali Pedram, Jin Kyung Kim

Cardiovasc Res. 2011 Jan 1; 89(1): 119–128. Published online 2010 Aug 19. doi: 10.1093/cvr/cvq265

PMCID:: PMC3002868

Abstract Article PDF–545K

Select item 21330908.

SAPK2/p38-dependent F-Actin Reorganization Regulates Early Membrane Blebbing during Stress-induced Apoptosis

Jacques Huot, François Houle, Simon Rousseau, Réna G. Deschesnes, Girish M. Shah, Jacques Landry

J Cell Biol. 1998 Nov 30; 143(5): 1361–1373. doi: 10.1083/jcb.143.5.1361

PMCID:: PMC2133090

Abstract Article PDF–3.0M

Select item 11696369.

Activation of stress-activated protein kinase-3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); comparison of the specificities of SAPK3 and SAPK2 (RK/p38).

A Cuenda, P Cohen, V Buée-Scherrer, M Goedert

EMBO J. 1997 Jan 15; 16(2): 295–305. doi: 10.1093/emboj/16.2.295

PMCID:: PMC1169636

Summary PDF–527K

Select item 684459810.

Roles of p38α and p38β mitogen-activated protein kinase isoforms in human malignant melanoma A375 cells

Su-Ying Wen, Shi-Yann Cheng, Shang-Chuan Ng, Ritu Aneja, Chih-Jung Chen, Chih-Yang Huang, Wei-Wen Kuo

Int J Mol Med. 2019 Dec; 44(6): 2123–2132. Published online 2019 Oct 24. doi: 10.3892/ijmm.2019.4383

PMCID:: PMC6844598

Abstract Article PDF–919K

Select item 665872011.

Knocking down of LINC01220 inhibits proliferation and induces apoptosis of endometrial carcinoma through silencing MAPK11

Yong Li, Chengcai Kong, Chaoying Wu, Yingqiao Wang, Boqun Xu, Shenglian Liang, Xiaoyan Ying

Biosci Rep. 2019 Jul 31; 39(7): BSR20181794. Prepublished online 2019 May 23. Published online 2019 Jul 26. doi: 10.1042/BSR20181794

PMCID:: PMC6658720

Abstract Article PDF–1.1M

Select item 485969312.

p38β Mitogen-Activated Protein Kinase Modulates Its Own Basal Activity by Autophosphorylation of the Activating Residue Thr180 and the Inhibitory Residues Thr241 and Ser261

Jonah Beenstock, Dganit Melamed, Navit Mooshayef, Dafna Mordechay, Benjamin P. Garfinkel, Natalie G. Ahn, Arie Admon, David Engelberg

Mol Cell Biol. 2016 May 15; 36(10): 1540–1554. Prepublished online 2016 Mar 14. Published online 2016 May 2. doi: 10.1128/MCB.01105-15

PMCID:: PMC4859693

Abstract Article PDF–2.9M

Select item 374220013.

p38β, A Novel Regulatory Target of Pokemon in Hepatic Cells

Zhe Chen, Feng Liu, Nannan Zhang, Deliang Cao, Min Liu, Ying Tan, Yuyang Jiang

Int J Mol Sci. 2013 Jul; 14(7): 13511–13524. Published online 2013 Jun 27. doi: 10.3390/ijms140713511

PMCID:: PMC3742200

Abstract Article PDF–1.3M

Select item 313788114.

Effect of p38 MAP kinases on contractility and ischemic injury in intact heart

HR Cross, M Li, BG Petrich, E Murphy, Y Wang, Ch Steenbergen

Acta Physiol Hung. Author manuscript; available in PMC 2011 Jul 16.

Published in final edited form as: Acta Physiol Hung. 2009 Sep; 96(3): 307–323. doi: 10.1556/APhysiol.96.2009.3.5

PMCID:: PMC3137881

Abstract Article PDF–833K

Select item 272969015.

Isoflavone genistein protects human vascular endothelial cells against tumor necrosis factor-α-induced apoptosis through the p38β mitogen-activated protein kinase

Hongwei Si, Dongmin Liu

Apoptosis. Author manuscript; available in PMC 2009 Aug 20.

Published in final edited form as: Apoptosis. 2009 Jan; 14(1): 66–76. doi: 10.1007/s10495-008-0283-9

PMCID:: PMC2729690

Abstract Article PDF–1.2M

Select item 790114216.

Phosphorylation of SNX27 by MAPK11/14 links cellular stress–signaling pathways with endocytic recycling

Lejiao Mao, Chenyi Liao, Jiao Qin, Yanqiu Gong, Yifei Zhou, Shasha Li, Zhe Liu, Huaqing Deng, Wankun Deng, Qingxiang Sun, Xianming Mo, Yu Xue, Daniel D. Billadeau, Lunzhi Dai, Guohui Li, Da Jia

J Cell Biol. 2021 Apr 5; 220(4): e202010048. Published online 2021 Feb 19. doi: 10.1083/jcb.202010048

PMCID:: PMC7901142

Abstract Article PDF–7.2M

Select item 785048517.

Pseudomonas aeruginosa induces p38MAP kinase-dependent IL-6 and CXCL8 release from bronchial epithelial cells via a Syk kinase pathway

Matthew S. Coates, Eric W. F. W. Alton, Garth W. Rapeport, Jane C. Davies, Kazuhiro Ito

PLoS One. 2021; 16(2): e0246050. Published online 2021 Feb 1. doi: 10.1371/journal.pone.0246050

PMCID:: PMC7850485

Abstract Article PDF–1.8M

Select item 723715018.

HuR stabilizes HTT mRNA via interacting with its exon 11 in a mutant HTT-dependent manner

Quan Zhao, Chen Li, Meng Yu, Yimin Sun, Jian Wang, Lixiang Ma, Xiaoli Sun, Boxun Lu

RNA Biol. 2020; 17(4): 500–516. Published online 2020 Jan 13. doi: 10.1080/15476286.2020.1712894

PMCID:: PMC7237150

Abstract Article PDF–17M

Select item 690472719.

Circ_0001955 facilitates hepatocellular carcinoma (HCC) tumorigenesis by sponging miR-516a-5p to release TRAF6 and MAPK11

Zhicheng Yao, Ruiyun Xu, Lin Yuan, Mingxing Xu, Haiyun Zhuang, Yanjie Li, Yi Zhang, Nan Lin

Cell Death Dis. 2019 Dec; 10(12): 945. Published online 2019 Dec 10. doi: 10.1038/s41419-019-2176-y

PMCID:: PMC6904727

Abstract Article PDF–2.0M

Select item 571740020.

Suppression of MAPK11 or HIPK3 reduces mutant Huntingtin levels in Huntington's disease models

Meng Yu, Yuhua Fu, Yijiang Liang, Haikun Song, Yao Yao, Peng Wu, Yuwei Yao, Yuyin Pan, Xue Wen, Lixiang Ma, Saiyin Hexige, Yu Ding, Shouqing Luo, Boxun Lu

Cell Res. 2017 Dec; 27(12): 1441–1465. Published online 2017 Oct 13. doi: 10.1038/cr.2017.113