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Select item 94344041.

BOK controls ER proteostasis and physiological ER stress responses in neurons

Franziska Walter, Beatrice D’Orsi, Anagha Jagannathan, Heiko Dussmann, Jochen H. M. Prehn

Front Cell Dev Biol. 2022; 10: 915065. Published online 2022 Aug 15. doi: 10.3389/fcell.2022.915065

PMCID:: PMC9434404

Abstract Article PDF–3.1M

Select item 80047602.

Loss of BOK Has a Minor Impact on Acetaminophen Overdose-Induced Liver Damage in Mice

Samara Naim, Yuniel Fernandez-Marrero, Simone de Brot, Daniel Bachmann, Thomas Kaufmann

Int J Mol Sci. 2021 Mar; 22(6): 3281. Published online 2021 Mar 23. doi: 10.3390/ijms22063281

PMCID:: PMC8004760

Abstract Article PDF–2.9M

Select item 79952163.

BOK controls apoptosis by Ca²⁺ transfer through ER-mitochondrial contact sites

Marcos A. Carpio, Robert E. Means, Allison L. Brill, Alva Sainz, Barbara E. Ehrlich, Samuel G. Katz

Cell Rep. Author manuscript; available in PMC 2021 Mar 26.

Published in final edited form as: Cell Rep. 2021 Mar 9; 34(10): 108827. doi: 10.1016/j.celrep.2021.108827

PMCID:: PMC7995216

Abstract Article PDF–2.3M

Select item 67020644.

BOK Promotes Erythropoiesis in a Mouse Model of Myelodysplastic Syndrome

Seong-Ho Kang, Oscar Perales, Michael Michuad, Samuel G. Katz

Ann Hematol. Author manuscript; available in PMC 2020 Sep 1.

Published in final edited form as: Ann Hematol. 2019 Sep; 98(9): 2089–2096. Published online 2019 Jun 16. doi: 10.1007/s00277-019-03726-7

PMCID:: PMC6702064

Abstract Article PDF–1.3M

Select item 66817085.

BCL-2 family protein BOK is a positive regulator of uridine metabolism in mammals

Rahul Srivastava, Zhipeng Cao, Christina Nedeva, Samara Naim, Daniel Bachmann, Tatiana Rabachini, Lahiru Gangoda, Sanjay Shahi, Jason Glab, Joseph Menassa, Laura Osellame, Tao Nelson, Yuniel Fernandez-Marrero, Fiona Brown, Andrew Wei, Francine Ke, Lorraine O’Reilly, Marcel Doerflinger, Cody Allison, Andrew Kueh, Rob Ramsay, Brian J. Smith, Suresh Mathivanan, Thomas Kaufmann, Hamsa Puthalakath

Proc Natl Acad Sci U S A. 2019 Jul 30; 116(31): 15469–15474. Published online 2019 Jul 16. doi: 10.1073/pnas.1904523116

PMCID:: PMC6681708

Abstract Article PDF–1.4M

Select item 58641946.

BOK promotes chemical-induced hepatocarcinogenesis in mice

Tatiana Rabachini, Yuniel Fernandez-Marrero, Matteo Montani, Giulio Loforese, Valentina Sladky, Zhaoyue He, Daniel Bachmann, Simone Wicki, Andreas Villunger, Deborah Stroka, Thomas Kaufmann

Cell Death Differ. 2018 Apr; 25(4): 706–718. Published online 2017 Dec 11. doi: 10.1038/s41418-017-0008-0

PMCID:: PMC5864194

Abstract Article PDF–3.1M

Select item 33540607.

BCL-2 family member BOK is widely expressed but its loss has only minimal impact in mice

F Ke, A Voss, J B Kerr, L A O'Reilly, L Tai, N Echeverry, P Bouillet, A Strasser, T Kaufmann

Cell Death Differ. 2012 Jun; 19(6): 915–925. Published online 2012 Jan 27. doi: 10.1038/cdd.2011.210

Correction in:: Cell Death Differ. 2013 Jan; 20(1): 183.

PMCID:: PMC3354060

Abstract Article PDF–814K

Select item 72242028.

Bok regulates mitochondrial fusion and morphology

Jacqualyn J. Schulman, Laura M. Szczesniak, Eric N. Bunker, Heather A. Nelson, Michael W. Roe, Larry E. Wagner, II, David I. Yule, Richard J. H. Wojcikiewicz

Cell Death Differ. 2019 Dec; 26(12): 2682–2694. Published online 2019 Apr 11. doi: 10.1038/s41418-019-0327-4

PMCID:: PMC7224202

Abstract Article PDF–4.0M

Select item 58338569.

Ceramide-induced BOK promotes mitochondrial fission in preeclampsia

Jonathan Ausman, Joelcio Abbade, Leonardo Ermini, Abby Farrell, Andrea Tagliaferro, Martin Post, Isabella Caniggia

Cell Death Dis. 2018 Mar; 9(3): 298. Published online 2018 Feb 20. doi: 10.1038/s41419-018-0360-0

PMCID:: PMC5833856

Abstract Article PDF–3.3M

Select item 488244910.

The Stability and Expression Level of Bok Are Governed by Binding to Inositol 1,4,5-Trisphosphate Receptors

Jacqualyn J. Schulman, Forrest A. Wright, Xiaobing Han, Eric J. Zluhan, Laura M. Szczesniak, Richard J. H. Wojcikiewicz

J Biol Chem. 2016 May 27; 291(22): 11820–11828. Published online 2016 Apr 6. doi: 10.1074/jbc.M115.711242

PMCID:: PMC4882449

Abstract Article PDF–1.8M

Select item 446674411.

BCL-2 family member BOK promotes apoptosis in response to endoplasmic reticulum stress

Marcos A. Carpio, Michael Michaud, Wenping Zhou, Jill K. Fisher, Loren D. Walensky, Samuel G. Katz

Proc Natl Acad Sci U S A. 2015 Jun 9; 112(23): 7201–7206. Published online 2015 May 26. doi: 10.1073/pnas.1421063112

PMCID:: PMC4466744

Abstract Article PDF–2.0M

Select item 364723612.

Intracellular localization of the BCL-2 family member BOK and functional implications

N Echeverry, D Bachmann, F Ke, A Strasser, H U Simon, T Kaufmann

Cell Death Differ. 2013 Jun; 20(6): 785–799. Published online 2013 Feb 22. doi: 10.1038/cdd.2013.10

PMCID:: PMC3647236

Abstract Article PDF–3.4M

Select item 213479013.

Jose M. Rodriguez, Michele A. Glozak, Yihong Ma, W. Douglas Cress

J Biol Chem. Author manuscript; available in PMC 2007 Dec 12.

Published in final edited form as: J Biol Chem. 2006 Aug 11; 281(32): 22729–22735. Published online 2006 Jun 13. doi: 10.1074/jbc.M604705200

PMCID:: PMC2134790

Abstract Article PDF–1.2M

Select item 369854314.

Consequences of the combined loss of BOK and BAK or BOK and BAX

F Ke, P Bouillet, T Kaufmann, A Strasser, J Kerr, A K Voss

Cell Death Dis. 2013 Jun; 4(6): e650. Published online 2013 Jun 6. doi: 10.1038/cddis.2013.176

PMCID:: PMC3698543

Abstract Article PDF–2.5M

Select item 660182215.

Bok Is Not Pro-Apoptotic But Suppresses Poly ADP-Ribose Polymerase-Dependent Cell Death Pathways and Protects against Excitotoxic and Seizure-Induced Neuronal Injury

Beatrice D'Orsi, Tobias Engel, Shona Pfeiffer, Saheli Nandi, Thomas Kaufmann, David C. Henshall, Jochen H. M. Prehn

J Neurosci. 2016 Apr 20; 36(16): 4564–4578. doi: 10.1523/JNEUROSCI.3780-15.2016

PMCID:: PMC6601822

Abstract Article PDF–2.9M

Select item 899122516.

Some mice lacking intrinsic, as well as death receptor induced apoptosis and necroptosis, can survive to adulthood

Francine F. S. Ke, Kerstin Brinkmann, Anne K. Voss, Andreas Strasser

Cell Death Dis. 2022 Apr; 13(4): 317. Published online 2022 Apr 7. doi: 10.1038/s41419-022-04731-x

PMCID:: PMC8991225

Abstract Article PDF–1.1M

Select item 685605717.

NMDA Receptor in Vasopressin 1b Neurons Is Not Required for Short-Term Social Memory, Object Memory or Aggression

Sarah K. Williams Avram, Heon-Jin Lee, Jarrett Fastman, Adi Cymerblit-Sabba, Adam Smith, Matthew Vincent, June Song, Michael C. Granovetter, Su-Hyun Lee, Nicholas I. Cilz, Michelle Stackmann, Rahul Chaturvedi, W. Scott Young

Front Behav Neurosci. 2019; 13: 218. Published online 2019 Nov 8. doi: 10.3389/fnbeh.2019.00218

PMCID:: PMC6856057

Abstract Article PDF–12M

Select item 375719818.

The Bcl-2 Protein Family Member Bok Binds to the Coupling Domain of Inositol 1,4,5-Trisphosphate Receptors and Protects Them from Proteolytic Cleavage

Jacqualyn J. Schulman, Forrest A. Wright, Thomas Kaufmann, Richard J. H. Wojcikiewicz

J Biol Chem. 2013 Aug 30; 288(35): 25340–25349. Published online 2013 Jul 24. doi: 10.1074/jbc.M113.496570

PMCID:: PMC3757198

Abstract Article PDF–2.5M

Select item 336492119.

NLRP5 Mediates Mitochondrial Function in Mouse Oocytes and Embryos

Roxanne Fernandes, Chiharu Tsuda, Alagammal L. Perumalsamy, Taline Naranian, Jasmine Chong, Beth M. Acton, Zhi-Bin Tong, Lawrence M. Nelson, Andrea Jurisicova

Biol Reprod. 2012 May; 86(5): 138. Published online 2012 Feb 22. doi: 10.1095/biolreprod.111.093583

PMCID:: PMC3364921

Abstract Article PDF–555K

Select item 501836020.

BOK Is a Non-Canonical BCL-2 Family Effector of Apoptosis Regulated by ER-Associated Degradation

Fabien Llambi, Yue-Ming Wang, Bernadette Victor, Mao Yang, Desiree M. Schneider, Sébastien Gingras, Melissa J. Parsons, Janet H. Zheng, Scott A. Brown, Stéphane Pelletier, Tudor Moldoveanu, Taosheng Chen, Douglas R. Green

Cell. Author manuscript; available in PMC 2017 Apr 7.

Published in final edited form as: Cell. 2016 Apr 7; 165(2): 421–433. Published online 2016 Mar 3. doi: 10.1016/j.cell.2016.02.026

PMCID:: PMC5018360

Abstract Article PDF–1.6M

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