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Select item 102423421.

ITGA5 promotes tumor angiogenesis in cervical cancer

Xiaohan Xu, Lulu Shen, Wenhan Li, Xiaoli Liu, Ping Yang, Jing Cai

Cancer Med. 2023 May; 12(10): 11983–11999. Published online 2023 Mar 31. doi: 10.1002/cam4.5873

PMCID:: PMC10242342

Abstract Article PDF–14M

Select item 99126482.

The members of the miR-148/152 family inhibit cancer stem cell-like properties in gastric cancer via negative regulation of ITGA5

Xiaoying Li, Lin Li, Jiangying Wu

J Transl Med. 2023; 21: 105. Published online 2023 Feb 10. doi: 10.1186/s12967-023-03894-1

PMCID:: PMC9912648

Abstract Article PDF–1.8M

Select item 95266183.

ITGA5 Promotes Tumor Progression through the Activation of the FAK/AKT Signaling Pathway in Human Gastric Cancer

Jun-fu Wang, Ye-yang Chen, Si-wen Zhang, Kun Zhao, Yue Qiu, Ye Wang, Jian-cheng Wang, Zhu Yu, Bo-pei Li, Zheng Wang, Jun-qiang Chen

Oxid Med Cell Longev. 2022; 2022: 8611306. Published online 2022 Sep 24. doi: 10.1155/2022/8611306

PMCID:: PMC9526618

Abstract Article PDF–2.7M

Select item 79538224.

ITGA5 is a prognostic biomarker and correlated with immune infiltration in gastrointestinal tumors

Hai Zhu, Gang Wang, Haixing Zhu, Aman Xu

BMC Cancer. 2021; 21: 269. Published online 2021 Mar 12. doi: 10.1186/s12885-021-07996-1

PMCID:: PMC7953822

Abstract Article PDF–3.6M

Select item 78923445.

Integrin alpha5 in human breast cancer is a mediator of bone metastasis and a therapeutic target for the treatment of osteolytic lesions

Francesco Pantano, Martine Croset, Keltouma Driouch, Natalia Bednarz-Knoll, Michele Iuliani, Giulia Ribelli, Edith Bonnelye, Harriet Wikman, Sandra Geraci, Florian Bonin, Sonia Simonetti, Bruno Vincenzi, Saw See Hong, Sofia Sousa, Klaus Pantel, Giuseppe Tonini, Daniele Santini, Philippe Clézardin

Oncogene. 2021; 40(7): 1284–1299. Published online 2021 Jan 8. doi: 10.1038/s41388-020-01603-6

PMCID:: PMC7892344

Abstract Article PDF–13M

Select item 68891696.

Integrin alpha-5 subunit is critical for the early stages of human pluripotent stem cell cardiac differentiation

Gabriel Neiman, María Agustina Scarafía, Alejandro La Greca, Natalia L. Santín Velazque, Ximena Garate, Ariel Waisman, Alan M. Möbbs, Tais Hanae Kasai-Brunswick, Fernanda Mesquita, Daiana Martire-Greco, Lucía N. Moro, Carlos Luzzani, Adriana Bastos Carvalho, Gustavo E. Sevlever, Antonio Campos de Carvalho, Alejandra S. Guberman, Santiago G. Miriuka

Sci Rep. 2019; 9: 18077. Published online 2019 Dec 2. doi: 10.1038/s41598-019-54352-2

PMCID:: PMC6889169

Abstract Article PDF–3.7M

Select item 68875867.

Integrin α5 subunit is required for the tumor supportive role of fibroblasts in colorectal adenocarcinoma and serves as a potential stroma prognostic marker

Ling Lu, Ruting Xie, Rong Wei, Chunmiao Cai, Dexi Bi, Dingzi Yin, Hu Liu, Jiayi Zheng, Youhua Zhang, Feifei Song, Yaohui Gao, Linhua Tan, Qing Wei, Huanlong Qin

Mol Oncol. 2019 Dec; 13(12): 2697–2714. Published online 2019 Nov 6. doi: 10.1002/1878-0261.12583

PMCID:: PMC6887586

Abstract Article PDF–10M

Select item 67264508.

ITGA5 inhibition in pancreatic stellate cells attenuates desmoplasia and potentiates efficacy of chemotherapy in pancreatic cancer

Praneeth R. Kuninty, Ruchi Bansal, Susanna W. L. De Geus, Deby F. Mardhian, Jonas Schnittert, Joop van Baarlen, Gert Storm, Maarten F. Bijlsma, Hanneke W. van Laarhoven, Josbert M. Metselaar, Peter J. K. Kuppen, Alexander L. Vahrmeijer, Arne Östman, Cornelis F. M. Sier, Jai Prakash

Sci Adv. 2019 Sep; 5(9): eaax2770. Published online 2019 Sep 4. doi: 10.1126/sciadv.aax2770

PMCID:: PMC6726450

Abstract Article PDF–9.4M

Select item 64005379.

Heterotypic CAF-tumor spheroids promote early peritoneal metastatis of ovarian cancer

Qinglei Gao, Zongyuan Yang, Sen Xu, Xiaoting Li, Xin Yang, Ping Jin, Yi Liu, Xiaoshui Zhou, Taoran Zhang, Cheng Gong, Xiao Wei, Dan Liu, Chaoyang Sun, Gang Chen, Junbo Hu, Li Meng, Jianfeng Zhou, Kenjiro Sawada, Robert Fruscio, Thomas W. Grunt, Jörg Wischhusen, Víctor Manuel Vargas-Hernández, Bhavana Pothuri, Robert L. Coleman

J Exp Med. 2019 Mar 4; 216(3): 688–703. doi: 10.1084/jem.20180765

Correction in:: J Exp Med. 2019 Oct 7; 216(10): 2448.

PMCID:: PMC6400537

Abstract Article PDF–3.2M

Select item 570649610.

Deoxycholic acid promotes development of gastroesophageal reflux disease and Barrett's oesophagus by modulating integrin‐αv trafficking

David O. Prichard, Anne Marie Byrne, James O. Murphy, John V. Reynolds, Jacintha O'Sullivan, Ronan Feighery, Brendan Doyle, Osama Sharaf Eldin, Stephen P. Finn, Aoife Maguire, Deirdre Duff, Dermot P. Kelleher, Aideen Long

J Cell Mol Med. 2017 Dec; 21(12): 3612–3625. Published online 2017 Sep 22. doi: 10.1111/jcmm.13271

PMCID:: PMC5706496

Abstract Article PDF–3.2M

Select item 551054311.

Hypoxia Selectively Enhances Integrin Receptor Expression to Promote Metastasis

Julia A. Ju, Inês Godet, I Chae Ye, Jungmin Byun, Hasini Jayatilaka, Sun Joo Lee, Lisha Xiang, Debangshu Samanta, Meng Horng Lee, Pei-Hsun Wu, Denis Wirtz, Gregg L. Semenza, Daniele M. Gilkes

Mol Cancer Res. Author manuscript; available in PMC 2017 Sep 1.

Published in final edited form as: Mol Cancer Res. 2017 Jun; 15(6): 723–734. Published online 2017 Feb 17. doi: 10.1158/1541-7786.MCR-16-0338

PMCID:: PMC5510543

Abstract Article PDF–1.0M

Select item 539427312.

A Key Regulator of Cell Adhesion: Identification and Characterization of Important N-Glycosylation Sites on Integrin α5 for Cell Migration

Qinglei Hang, Tomoya Isaji, Sicong Hou, Yuqin Wang, Tomohiko Fukuda, Jianguo Gu

Mol Cell Biol. 2017 May 1; 37(9): e00558-16. Prepublished online 2017 Feb 6. Published online 2017 Apr 14. doi: 10.1128/MCB.00558-16

PMCID:: PMC5394273

Abstract Article PDF–3.0M

Select item 471354513.

Effect of ITGA5 down-regulation on the migration capacity of human dental pulp stem cells

Shuaimei Xu, Li Cui, Dandan Ma, Wenjuan Sun, Buling Wu

Int J Clin Exp Pathol. 2015; 8(11): 14425–14432. Published online 2015 Nov 1.

PMCID:: PMC4713545

Abstract Article PDF–1.3M

Select item 416040314.

THE FATE OF INTERNALIZED α5 INTEGRIN IS REGULATED BY MATRIX-CAPABLE FIBRONECTIN

Henry C. Hsia, Mohan R. Nair, Siobhan A. Corbett

J Surg Res. Author manuscript; available in PMC 2015 Oct 1.

Published in final edited form as: J Surg Res. 2014 Oct; 191(2): 268–279. Published online 2014 Jun 4. doi: 10.1016/j.jss.2014.05.084

PMCID:: PMC4160403

Abstract Article PDF–1.6M

Select item 396684815.

9-cis-Retinoic Acid and Troglitazone Impacts Cellular Adhesion, Proliferation, and Integrin Expression in K562 Cells

Amanda M. Hanson, Jessica Gambill, Venusa Phomakay, C. Tyler Staten, Melissa D. Kelley

PLoS One. 2014; 9(3): e93005. Published online 2014 Mar 26. doi: 10.1371/journal.pone.0093005

PMCID:: PMC3966848

Abstract Article PDF–1.5M

Select item 375713016.

Significance of Expression of ITGA5 and its Splice Variants in Acute Myeloid Leukemia: A Report from the Children’s Oncology Group

Roland B. Walter, George S. Laszlo, Todd A. Alonzo, Robert B. Gerbing, Shawn Levy, Matthew P. Fitzgibbon, Chelsea J. Gudgeon, Rhonda E. Ries, Kimberly H. Harrington, Susana C. Raimondi, Betsy A. Hirsch, Alan S. Gamis, Martin W. McIntosh, Soheil Meshinchi

Am J Hematol. Author manuscript; available in PMC 2014 Aug 1.

Published in final edited form as: Am J Hematol. 2013 Aug; 88(8): 694–702. Published online 2013 Jun 20. doi: 10.1002/ajh.23486

PMCID:: PMC3757130

Abstract Article PDF–2.5M

Select item 329043017.

Rv2468c, a novel Mycobacterium tuberculosis protein that costimulates human CD4⁺ T cells through VLA-5

Qing Li, Xuedong Ding, Jeremy J. Thomas, Clifford V. Harding, Nicole D. Pecora, Assem G. Ziady, Samuel Shank, W. Henry Boom, Christina L. Lancioni, Roxana E. Rojas

J Leukoc Biol. 2012 Feb; 91(2): 311–320. doi: 10.1189/jlb.0711364

PMCID:: PMC3290430

Abstract Article

Select item 304579518.

RNA interference-mediated knockdown of CD49e (α5 integrin chain) in human thymic epithelial cells modulates the expression of multiple genes and decreases thymocyte adhesion

Leandra Linhares-Lacerda, Marcelo Ribeiro-Alves, Ana Cristina Martins de Almeida Nogueira, Daniella Areas Mendes-da-Cruz, Danielle Aparecida Magalhães, Mireille Dardenne, Geraldo Aleixo Passos, Wilson Savino

BMC Genomics. 2010; 11(Suppl 5): S2. Published online 2010 Dec 22. doi: 10.1186/1471-2164-11-S5-S2

PMCID:: PMC3045795

Abstract Article PDF–1.4M

Select item 302199819.

Integrin α5β1 facilitates cancer cell invasion through enhanced contractile forces

Claudia Tanja Mierke, Benjamin Frey, Martina Fellner, Martin Herrmann, Ben Fabry

J Cell Sci. 2011 Feb 1; 124(3): 369–383. Published online 2011 Jan 11. doi: 10.1242/jcs.071985

PMCID:: PMC3021998

Abstract Article

Select item 277397320.

Priming integrin α5 promotes human mesenchymal stromal cell osteoblast differentiation and osteogenesis

Zahia Hamidouche, Olivia Fromigué, Jochen Ringe, Thomas Häupl, Pascal Vaudin, Jean-Christophe Pagès, Samer Srouji, Erella Livne, Pierre J. Marie

Proc Natl Acad Sci U S A. 2009 Nov 3; 106(44): 18587–18591. Published online 2009 Oct 20. doi: 10.1073/pnas.0812334106

PMCID:: PMC2773973

Abstract Article PDF–942K

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