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Select item 31644531.

Neuroprotective role of PrP^C against kainate-induced epileptic seizures and cell death depends on the modulation of JNK3 activation by GluR6/7–PSD-95 binding

Patricia Carulla, Ana Bribián, Alejandra Rangel, Rosalina Gavín, Isidro Ferrer, Carme Caelles, José Antonio del Río, Franc Llorens

Mol Biol Cell. 2011 Sep 1; 22(17): 3041–3054. doi: 10.1091/mbc.E11-04-0321

PMCID:: PMC3164453

Abstract Article PDF–1.7M

Select item 30609512.

Lack of neuroprotection against experimental glaucoma in c-Jun N-terminal kinase 3 knockout mice

Harry A. Quigley, Frances E. Cone, Scott E. Gelman, Zhiyong Yang, Janice L. Son, Ericka N. Oglesby, Mary E. Pease, Donald J. Zack

Exp Eye Res. Author manuscript; available in PMC 2012 Apr 1.

Published in final edited form as: Exp Eye Res. 2011 Apr; 92(4): 299–305. Published online 2011 Jan 25. doi: 10.1016/j.exer.2011.01.006

PMCID:: PMC3060951

Abstract Article PDF–1.2M

Select item 60000013.

Jnk2 deficiency increases the rate of glaucomatous neurodegeneration in ocular hypertensive DBA/2J mice

Jeffrey M. Harder, Pete A. Williams, Ileana Soto, Nicole E. Foxworth, Kimberly A. Fernandes, Nelson F. Freeburg, Richard T. Libby, Simon. W. M. John

Cell Death Dis. 2018 Jun; 9(6): 705. Published online 2018 Jun 13. doi: 10.1038/s41419-018-0705-8

PMCID:: PMC6000001

Abstract Article PDF–1.6M

Select item 46540544.

Genetic inhibition of JNK3 ameliorates spinal muscular atrophy

Naresh K. Genabai, Saif Ahmad, Zhanying Zhang, Xiaoting Jiang, Cynthia A. Gabaldon, Laxman Gangwani

Hum Mol Genet. 2015 Dec 15; 24(24): 6986–7004. Published online 2015 Sep 30. doi: 10.1093/hmg/ddv401

PMCID:: PMC4654054

Abstract Article PDF–2.1M

Select item 42994675.

Activation of TLR3 Promotes the Degeneration of Retinal Ganglion Cells by Upregulating the Protein Levels of JNK3

Shravan K. Chintala, Nahrain Putris, Mason Geno

Invest Ophthalmol Vis Sci. 2015 Jan; 56(1): 505–514. Published online 2015 Jan 19. doi: 10.1167/iovs.14-15539

PMCID:: PMC4299467

Abstract Article PDF–1.4M

Select item 34385226.

JNK3 perpetuates metabolic stress induced by Abeta peptides

Sung Ok Yoon, Dong Ju Park, Jae Cheon Ryu, Hatice Gulcin Ozer, Chhavy Tep, Yong Jae Shin, Tae Hee Lim, Lucia Pastorino, Ajaya J. Kunwar, James C. Walton, Alan H. Nagahara, Kun Ping Lu, Randy J. Nelson, Mark H. Tuszynski, Kun Huang

Neuron. Author manuscript; available in PMC 2013 Sep 6.

Published in final edited form as: Neuron. 2012 Sep 6; 75(5): 824–837. doi: 10.1016/j.neuron.2012.06.024

PMCID:: PMC3438522

Abstract Article PDF–6.1M

Select item 26325847.

JNK2 and JNK3 combined are essential for apoptosis in dopamine neurons of the substantia nigra, but are not required for axon degeneration

Vincent Ries, Robert M. Silva, Tinmarla F. Oo, Hsiao-Chun Cheng, Margarita Rzhetskaya, Nikolai Kholodilov, Richard A. Flavell, Chia-Yi Kuan, Pasko Rakic, Robert E. Burke

J Neurochem. Author manuscript; available in PMC 2009 Jan 28.

Published in final edited form as: J Neurochem. 2008 Dec; 107(6): 1578–1588. Published online 2008 Nov 5. doi: 10.1111/j.1471-4159.2008.05713.x

PMCID:: PMC2632584

Abstract Article PDF–2.4M

Select item 21718098.

Sunday Driver links axonal transport to damage signaling

Valeria Cavalli, Pekka Kujala, Judith Klumperman, Lawrence S.B. Goldstein

J Cell Biol. 2005 Feb 28; 168(5): 775–787. doi: 10.1083/jcb.200410136

PMCID:: PMC2171809

Abstract Article PDF–6.4M

Select item 67628929.

β-Amyloid Induces Neuronal Apoptosis Via a Mechanism that Involves the c-Jun N-Terminal Kinase Pathway and the Induction of Fas Ligand

Yoshiyuki Morishima, Yukiko Gotoh, Janine Zieg, Tamera Barrett, Hiromichi Takano, Richard Flavell, Roger J. Davis, Yasufumi Shirasaki, Michael E. Greenberg

J Neurosci. 2001 Oct 1; 21(19): 7551–7560. doi: 10.1523/JNEUROSCI.21-19-07551.2001

PMCID:: PMC6762892

Abstract Article PDF–735K

Select item 437783910.

EphrinB2 controls vessel pruning through STAT1-JNK3 signaling

Ombretta Salvucci, Hidetaka Ohnuki, Dragan Maric, Xu Hou, Xuri Li, Sung Ok Yoon, Marta Segarra, Charles G. Eberhart, Amparo Acker-Palmer, Giovanna Tosato

Nat Commun. Author manuscript; available in PMC 2015 Sep 26.

Published in final edited form as: Nat Commun. 2015; 6: 6576. Published online 2015 Mar 26. doi: 10.1038/ncomms7576

PMCID:: PMC4377839

Abstract Article PDF–4.3M

Select item 384248811.

Hippocampal c-Jun-N-Terminal Kinases Serve as Negative Regulators of Associative Learning

Tessi Sherrin, Thomas Blank, Cathrin Hippel, Martin Rayner, Roger J. Davis, Cedomir Todorovic

J Neurosci. 2010 Oct 6; 30(40): 13348–13361. doi: 10.1523/JNEUROSCI.3492-10.2010

PMCID:: PMC3842488

Abstract Article PDF–3.4M

Select item 362827412.

Inhibition of c-Jun NH₂-terminal kinase stimulates mu-opioid receptor expression via p38 MAPK-mediated nuclear NF-κB activation in neuronal and non-neuronal cells

Yadav Wagley, Cheol Kyu Hwang, Hong-Yiou Lin, Angel F.Y. Kam, Ping-Yee Law, Horace H. Loh, Li-Na Wei

Biochim Biophys Acta. Author manuscript; available in PMC 2014 Jun 1.

Published in final edited form as: Biochim Biophys Acta. 2013 Jun; 1833(6): 1476–1488. Published online 2013 Feb 26. doi: 10.1016/j.bbamcr.2013.02.017

PMCID:: PMC3628274

Abstract Article PDF–1.9M

Select item 315260013.

Activity of all JNK isoforms contributes to neurite growth in spiral ganglion neurons

Patrick J. Atkinson, Chang-Hyun Cho, Marlan R. Hansen, Steven H. Green

Hear Res. Author manuscript; available in PMC 2012 Aug 1.

Published in final edited form as: Hear Res. 2011 Aug; 278(1-2): 77–85. Published online 2011 May 1. doi: 10.1016/j.heares.2011.04.011

PMCID:: PMC3152600

Abstract Article PDF–1.1M

Select item 29994714.

A critical role of neural-specific JNK3 for ischemic apoptosis

Chia-Yi Kuan, Alan J. Whitmarsh, Derek D. Yang, Guanghong Liao, Aryn J. Schloemer, Chen Dong, Jue Bao, Kenneth J. Banasiak, Gabriel G. Haddad, Richard A. Flavell, Roger J. Davis, Pasko Rakic

Proc Natl Acad Sci U S A. 2003 Dec 9; 100(25): 15184–15189. Published online 2003 Dec 1. doi: 10.1073/pnas.2336254100

PMCID:: PMC299947

Abstract Article PDF–799K

Select item 20445815.

c-Jun N-terminal kinases (JNK) antagonize cardiac growth through cross-talk with calcineurin–NFAT signaling

Qiangrong Liang, Orlando F. Bueno, Benjamin J. Wilkins, Chia-Yi Kuan, Ying Xia, Jeffery D. Molkentin

EMBO J. 2003 Oct 1; 22(19): 5079–5089. doi: 10.1093/emboj/cdg474

PMCID:: PMC204458

Abstract Article PDF–412K

Select item 674899116.

Neural JNK3 regulates blood flow recovery after hindlimb ischemia in mice via an Egr1/Creb1 axis

Shashi Kant, Siobhan M. Craige, Kai Chen, Michaella M. Reif, Heather Learnard, Mark Kelly, Amada D. Caliz, Khanh-Van Tran, Kasmir Ramo, Owen M. Peters, Marc Freeman, Roger J. Davis, John F. Keaney, Jr.

Nat Commun. 2019; 10: 4223. Published online 2019 Sep 17. doi: 10.1038/s41467-019-11982-4

PMCID:: PMC6748991

Abstract Article PDF–2.9M

Select item 586418717.

APP upregulation contributes to retinal ganglion cell degeneration via JNK3

Chao Liu, Cheng-Wu Zhang, Yi Zhou, Wan Qing Wong, Liying Corinne Lee, Wei Yi Ong, Sung Ok Yoon, Wanjin Hong, Xin-Yuan Fu, Tuck Wah Soong, Edward H. Koo, Lawrence W. Stanton, Kah-Leong Lim, Zhi-Cheng Xiao, Gavin S. Dawe

Cell Death Differ. 2018 Apr; 25(4): 661–676. Published online 2017 Dec 13. doi: 10.1038/s41418-017-0005-3

PMCID:: PMC5864187

Abstract Article PDF–2.0M

Select item 562840818.

KLF9 and JNK3 Interact to Suppress Axon Regeneration in the Adult CNS

Akintomide Apara, Joana Galvao, Yan Wang, Murray Blackmore, Allison Trillo, Keiichiro Iwao, Dale P. Brown, Jr., Kimberly A. Fernandes, Abigail Huang, Tu Nguyen, Masoumeh Ashouri, Xiong Zhang, Peter X. Shaw, Noelia J. Kunzevitzky, Darcie L. Moore, Richard T. Libby, Jeffrey L. Goldberg

J Neurosci. 2017 Oct 4; 37(40): 9632–9644. doi: 10.1523/JNEUROSCI.0643-16.2017

PMCID:: PMC5628408

Abstract Article PDF–4.6M

Select item 479894719.

Excitatory transmission onto AgRP neurons is regulated by cJun NH₂-terminal kinase 3 in response to metabolic stress

Santiago Vernia, Caroline Morel, Joseph C Madara, Julie Cavanagh-Kyros, Tamera Barrett, Kathryn Chase, Norman J Kennedy, Dae Young Jung, Jason K Kim, Neil Aronin, Richard A Flavell, Bradford B Lowell, Roger J Davis

eLife. 2016; 5: e10031. Published online 2016 Feb 24. doi: 10.7554/eLife.10031

PMCID:: PMC4798947

Abstract Article PDF–3.6M

Select item 449130820.

Neuronal c-Jun is required for successful axonal regeneration, but the effects of phosphorylation of its N-terminus are moderate

Crystal A Ruff, Nils Staak, Smriti Patodia, Mark Kaswich, Eridan Rocha-Ferreira, Clive Da Costa, Stephan Brecht, Milan Makwana, Xavier Fontana, Mariya Hristova, Prakasham Rumajogee, Matthias Galiano, Marion Bohatschek, Thomas Herdegen, Axel Behrens, Gennadij Raivich

J Neurochem. 2012 May; 121(4): 607–618. doi: 10.1111/j.1471-4159.2012.07706.x