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Select item 96715621.

Association of salivary alpha-2-macroglobulin with glycemia and glycated hemoglobin in type 2 diabetes mellitus: a systematic review and meta-analysis study

Douglas Carvalho Caixeta, Pedro Rogério Camargos Pennisi, Douglas Vieira Moura, Marjorie Adriane Costa Nunes, Foued Salmen Espindola, Cauane Blumenberg, Luiz Renato Paranhos, Robinson Sabino-Silva

Sao Paulo Med J. 2022 Nov-Dec; 140(6): 818–828. Published online 2022 Sep 12. doi: 10.1590/1516-3180.2021.0816.R2.19052022

PMCID:: PMC9671562

Article PDF–512K

Select item 79051722.

The Role of Alpha 2 Macroglobulin in IgG-Aggregation and Chronic Activation of the Complement System in Patients With Chronic Lymphocytic Leukemia

Naseba Naseraldeen, Regina Michelis, Masad Barhoum, Judith Chezar, Tamar Tadmor, Ariel Aviv, Lev Shvidel, Adi Litmanovich, Mona Shehadeh, Galia Stemer, Ety Shaoul, Andrei Braester

Front Immunol. 2020; 11: 603569. Published online 2021 Feb 11. doi: 10.3389/fimmu.2020.603569

PMCID:: PMC7905172

Article PDF–2.0M

Select item 67368853.

Molecular form and concentration of serum α₂-macroglobulin in diabetes

Sonomi Yoshino, Kazumi Fujimoto, Tesshu Takada, Sayuki Kawamura, Junro Ogawa, Yuji Kamata, Yoshio Kodera, Masayoshi Shichiri

Sci Rep. 2019; 9: 12927. Published online 2019 Sep 10. doi: 10.1038/s41598-019-49144-7

PMCID:: PMC6736885

Article PDF–1.2M

Select item 65951084.

Relationship of α2‐Macroglobulin with Steroid‐Induced Femoral Head Necrosis: A Chinese Population‐Based Association Study in Southeast China

Shan‐hong Fang, Yong‐feng Li, Jia‐run Jiang, Peng Chen

Orthop Surg. 2019 Jun; 11(3): 481–486. Published online 2019 Jun 26. doi: 10.1111/os.12492

PMCID:: PMC6595108

Article PDF–766K

Select item 59061885.

Alpha-2-macroglobulin as a Promising Biological Marker of Endothelial Function

Ryo Shimomura, Tomohisa Nezu, Naohisa Hosomi, Shiro Aoki, Takamichi Sugimoto, Naoto Kinoshita, Mutsuko Araki, Tetsuya Takahashi, Hirofumi Maruyama, Masayasu Matsumoto

J Atheroscler Thromb. 2018 Apr 1; 25(4): 350–358. doi: 10.5551/jat.41335

PMCID:: PMC5906188

Article PDF–179K

Select item 58983786.

Blood-Based Biomarker Candidates of Cerebral Amyloid Using PiB PET in Non-Demented Elderly

Sarah Westwood, Emanuela Leoni, Abdul Hye, Steven Lynham, Mizanur R. Khondoker, Nicholas J. Ashton, Steven J. Kiddle, Alison L. Baird, Ricardo Sainz-Fuertes, Rufina Leung, John Graf, Cristina Tan Hehir, David Baker, Cristina Cereda, Chantal Bazenet, Malcolm Ward, Madhav Thambisetty, Simon Lovestone

J Alzheimers Dis. Author manuscript; available in PMC 2018 Apr 13.

Published in final edited form as: J Alzheimers Dis. 2016 Mar 29; 52(2): 561–572. doi: 10.3233/JAD-151155

PMCID:: PMC5898378

Article PDF–1.2M

Select item 57265087.

Alpha-2 macroglobulin in Alzheimer’s disease: a marker of neuronal injury through the RCAN1 pathway

VR Varma, S Varma, Y An, TJ Hohman, S Seddighi, R Casanova, A Beri, EB Dammer, NT Seyfried, O Pletnikova, A Moghekar, MR Wilson, JJ Lah, RJ O’Brien, AI Levey, JC Troncoso, MS Albert, M Thambisetty, Predictors of Cognitive Decline Among Normal Individuals (BIOCARD) and the Alzheimer’s Disease Neuroimaging Initiative (ADNI) studies

Mol Psychiatry. Author manuscript; available in PMC 2017 Dec 12.

Published in final edited form as: Mol Psychiatry. 2017 Jan; 22(1): 13–23. Published online 2016 Nov 22. doi: 10.1038/mp.2016.206

PMCID:: PMC5726508

Article PDF–899K

Select item 55913068.

Impaired fibrinolysis and lower levels of plasma α₂-macroglobulin are associated with an increased risk of severe asthma exacerbations

Stanislawa Bazan-Socha, Lucyna Mastalerz, Agnieszka Cybulska, Lech Zareba, Romy Kremers, Michal Zabczyk, Grazyna Pulka, Teresa Iwaniec, Jan G. Bazan, Coenraad Hemker, Anetta Undas

Sci Rep. 2017; 7: 11014. Published online 2017 Sep 8. doi: 10.1038/s41598-017-11467-8

PMCID:: PMC5591306

Article PDF–1.2M

Select item 48434599.

BK_Ca channel regulates calcium oscillations induced by alpha-2-macroglobulin in human myometrial smooth muscle cells

Monali Wakle-Prabagaran, Ramón A. Lorca, Xiaofeng Ma, Susan J. Stamnes, Chinwendu Amazu, Jordy J. Hsiao, Celeste M. Karch, Krzysztof L. Hyrc, Michael E. Wright, Sarah K. England

Proc Natl Acad Sci U S A. 2016 Apr 19; 113(16): E2335–E2344. Published online 2016 Apr 4. doi: 10.1073/pnas.1516863113

PMCID:: PMC4843459

Article PDF–1.6M

Select item 484171110.

Combined biomarkers discriminate a low likelihood of bacterial infection among surgical intensive care unit patients with suspected sepsis

Brendan J. Kelly, Ebbing Lautenbach, Irving Nachamkin, Susan E. Coffin, Jeffrey S. Gerber, Barry D. Fuchs, Charles Garrigan, Xiaoyan Han, Warren B. Bilker, Jacqueleen Wise, Pam Tolomeo, Jennifer H. Han, for the Centers for Disease Control and Prevention (CDC) Prevention Epicenters Program

Diagn Microbiol Infect Dis. Author manuscript; available in PMC 2017 May 1.

Published in final edited form as: Diagn Microbiol Infect Dis. 2016 May; 85(1): 109–115. Published online 2016 Jan 8. doi: 10.1016/j.diagmicrobio.2016.01.003

PMCID:: PMC4841711

Article PDF–1.4M

Select item 473063011.

A panel of glycoproteins as candidate biomarkers for early diagnosis and treatment evaluation of B-cell acute lymphoblastic leukemia

Marcio de Souza Cavalcante, José Camilo Torres-Romero, Marina Duarte Pinto Lobo, Frederico Bruno Mendes Batista Moreno, Leonardo Primo Bezerra, Diego Silva Lima, Jesamar Correia Matos, Renato de Azevedo Moreira, Ana Cristina de Oliveira Monteiro-Moreira

Biomark Res. 2016; 4: 1. Published online 2016 Jan 27. doi: 10.1186/s40364-016-0055-6

PMCID:: PMC4730630

Article PDF–892K

Select item 464970612.

Alpha-2-macroglobulin loaded microcapsules enhance human leukocyte functions and innate immune response

Donata Federici Canova, Anton M. Pavlov, Lucy V. Norling, Thomas Gobbetti, Sandra Brunelleschi, Pauline Le Fauder, Nicolas Cenac, Gleb B. Sukhorukov, Mauro Perretti

J Control Release. 2015 Nov 10; 217: 284–292. doi: 10.1016/j.jconrel.2015.09.021

PMCID:: PMC4649706

Article

Select item 456173413.

A Pro-Nerve Growth Factor (proNGF) and NGF Binding Protein, α₂-Macroglobulin, Differentially Regulates p75 and TrkA Receptors and Is Relevant to Neurodegeneration Ex Vivo and In Vivo

Pablo F. Barcelona, H. Uri Saragovi

Mol Cell Biol. 2015 Oct; 35(19): 3396–3408. Prepublished online 2015 Jul 27. Published online 2015 Sep 4. doi: 10.1128/MCB.00544-15

PMCID:: PMC4561734

Article PDF–1.9M

Select item 448972014.

α₂-Macroglobulin Can Crosslink Multiple Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) Molecules and May Facilitate Adhesion of Parasitized Erythrocytes

Liz Stevenson, Erik Laursen, Graeme J. Cowan, Betty Bandoh, Lea Barfod, David R. Cavanagh, Gregers R. Andersen, Lars Hviid

PLoS Pathog. 2015 Jul; 11(7): e1005022. Published online 2015 Jul 2. doi: 10.1371/journal.ppat.1005022

PMCID:: PMC4489720

Article PDF–4.5M

Select item 447787815.

Analysis of Alpha-2 Macroglobulin from the Long-Lived and Cancer-Resistant Naked Mole-Rat and Human Plasma

René Thieme, Susanne Kurz, Marlen Kolb, Tewodros Debebe, Susanne Holtze, Michaela Morhart, Klaus Huse, Karol Szafranski, Matthias Platzer, Thomas B. Hildebrandt, Gerd Birkenmeier

PLoS One. 2015; 10(6): e0130470. Published online 2015 Jun 23. doi: 10.1371/journal.pone.0130470

PMCID:: PMC4477878

Article PDF–3.2M

Select item 403420516.

Hypochlorite-induced structural modifications enhance the chaperone activity of human α₂-macroglobulin

Amy R. Wyatt, Janet R. Kumita, Richard W. Mifsud, Cherrie A. Gooden, Mark R. Wilson, Christopher M. Dobson

Proc Natl Acad Sci U S A. 2014 May 20; 111(20): E2081–E2090. Published online 2014 May 5. doi: 10.1073/pnas.1403379111

PMCID:: PMC4034205

Article PDF–1.3M

Select item 385930017.

Association of cerebrospinal fluid Aβ₄₂ with A2M gene in cognitively normal subjects

Steven P. Millard, Franziska Lutz, Ge Li, Douglas R. Galasko, Martin R. Farlow, Joseph F. Quinn, Jeffrey A. Kaye, James B. Leverenz, Debby Tsuang, Chang-En Yu, Elaine R. Peskind, Lynn M. Bekris

Neurobiol Aging. Author manuscript; available in PMC 2015 Feb 1.

Published in final edited form as: Neurobiol Aging. 2014 Feb; 35(2): 10.1016/j.neurobiolaging.2013.07.027. Published online 2013 Sep 4. doi: 10.1016/j.neurobiolaging.2013.07.027

PMCID:: PMC3859300

Article PDF–1.6M

Select item 377717718.

Urinary IgG and α2-Macroglobulin Are Powerful Predictors of Outcome and Responsiveness to Steroids and Cyclophosphamide in Idiopathic Focal Segmental Glomerulosclerosis with Nephrotic Syndrome

Claudio Bazzi, Virginia Rizza, Daniela Casellato, Gilda Stivali, Gregorio Rachele, Pietro Napodano, Maurizio Gallieni, Giuseppe D'Amico

Biomed Res Int. 2013; 2013: 941831. Published online 2013 Sep 4. doi: 10.1155/2013/941831

PMCID:: PMC3777177

Article PDF–626K

Select item 245927219.

Molecular Dissection of the Human α₂-Macroglobulin Subunit Reveals Domains with Antagonistic Activities in Cell Signaling

Elisabetta Mantuano, Gatambwa Mukandala, Xiaoqing Li, W. Marie Campana, Steven L. Gonias

J Biol Chem. 2008 Jul 18; 283(29): 19904–19911. doi: 10.1074/jbc.M801762200

PMCID:: PMC2459272

Article PDF–427K

Select item 226740520.

Human α₂-macroglobulin is composed of multiple domains, as predicted by homology with complement component C3

Ninh Doan, Peter G. W. Gettins

Biochem J. 2007 Oct 1; 407(Pt 1): 23–30. Prepublished online 2007 Jul 4. Published online 2007 Sep 12. doi: 10.1042/BJ20070764

PMCID:: PMC2267405

Article PDF–561K

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