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Select item 99173701.

Supt16 Haploinsufficiency Impairs PI3K/AKT/mTOR/Autophagy Pathway in Human Pluripotent Stem Cells Derived Neural Stem Cells

Junwen Wang, Ziyi Wang, Limeng Dai, Xintong Zhu, Xingying Guan, Junyi Wang, Jia Li, Mao Zhang, Yun Bai, Hong Guo

Int J Mol Sci. 2023 Feb; 24(3): 3035. Published online 2023 Feb 3. doi: 10.3390/ijms24033035

PMCID:: PMC9917370

Abstract Article PDF–16M

Select item 94916902.

De novo variants in SUPT16H cause neurodevelopmental disorders associated with corpus callosum abnormalities

Roya Bina, Dena Matalon, Brieana Fregeau, Jacqueline Joani Tarsitano, Ingvild Aukrust, Gunnar Houge, Renee Bend, Hannah Warren, Roger E Stevenson, Kyra Eva Stuurman, A James Barkovich, Elliott H. Sherr

J Med Genet. Author manuscript; available in PMC 2022 Sep 21.

Published in final edited form as: J Med Genet. 2020 Jul; 57(7): 461–465. Published online 2020 Jan 10. doi: 10.1136/jmedgenet-2019-106193

PMCID:: PMC9491690

Abstract Article PDF–173K

Select item 80881273.

Proteasomal Regulation of Mammalian SPT16 in Controlling Transcription

Amala Kaja, Abhinav Adhikari, Saswati Karmakar, Wanwei Zhang, Gerson Rothschild, Uttiya Basu, Surinder K. Batra, Judith K. Davie, Sukesh R. Bhaumik

Mol Cell Biol. 2021 Apr; 41(4): e00452-20. Prepublished online 2021 Feb 1. Published online 2021 Mar 24. doi: 10.1128/MCB.00452-20

PMCID:: PMC8088127

Abstract Article PDF–5.0M

Select item 99910014.

The fly homolog of SUPT16H, a gene associated with neurodevelopmental disorders, is required in a cell-autonomous fashion for cell survival

Mengqi Ma, Xi Zhang, Yiming Zheng, Shenzhao Lu, Xueyang Pan, Xiao Mao, Hongling Pan, Hyung-lok Chung, Hua Wang, Hong Guo, Hugo J Bellen

Hum Mol Genet. 2023 Mar 15; 32(6): 984–997. Published online 2022 Oct 18. doi: 10.1093/hmg/ddac259

PMCID:: PMC9991001

Abstract Article PDF–2.0M

Select item 98070505.

Human FACT subunits coordinate to catalyze both disassembly and reassembly of nucleosomes

Micah J. McCauley, Michael Morse, Nicole Becker, Qi Hu, Maria Victoria Botuyan, Emily Navarrete, Ran Huo, Uma M. Muthurajan, Ioulia Rouzina, Karolin Luger, Georges Mer, L. James Maher, III, Mark C. Williams

Cell Rep. Author manuscript; available in PMC 2023 Jan 2.

Published in final edited form as: Cell Rep. 2022 Dec 27; 41(13): 111858. doi: 10.1016/j.celrep.2022.111858

PMCID:: PMC9807050

Abstract Article PDF–3.1M

Select item 94108846.

FACT subunit SUPT16H associates with BRD4 and contributes to silencing of interferon signaling

Dawei Zhou, Zhenyu Wu, Jun-Gyu Park, Guillaume N Fiches, Tai-Wei Li, Qin Ma, Huachao Huang, Ayan Biswas, Luis Martinez-Sobrido, Netty G Santoso, Jian Zhu

Nucleic Acids Res. 2022 Aug 26; 50(15): 8700–8718. Published online 2022 Jul 29. doi: 10.1093/nar/gkac645

PMCID:: PMC9410884

Abstract Article PDF–8.9M

Select item 74415957.

FACT caught in the act of manipulating the nucleosome

Yang Liu, Keda Zhou, Naifu Zhang, Hui Wei, Yong Zi Tan, Zhening Zhang, Bridget Carragher, Clinton S. Potter, Sheena D'Arcy, Karolin Luger

Nature. Author manuscript; available in PMC 2020 Aug 21.

Published in final edited form as: Nature. 2020 Jan; 577(7790): 426–431. Published online 2019 Nov 27. doi: 10.1038/s41586-019-1820-0

PMCID:: PMC7441595

Abstract Article PDF–4.9M

Select item 46463778.

FACT Proteins, SUPT16H and SSRP1, Are Transcriptional Suppressors of HIV-1 and HTLV-1 That Facilitate Viral Latency

Huachao Huang, Netty Santoso, Derek Power, Sydney Simpson, Michael Dieringer, Hongyu Miao, Katerina Gurova, Chou-Zen Giam, Stephen J. Elledge, Jian Zhu

J Biol Chem. 2015 Nov 6; 290(45): 27297–27310. Published online 2015 Sep 16. doi: 10.1074/jbc.M115.652339

PMCID:: PMC4646377

Abstract Article PDF–2.1M

Select item 38413219.

Complex mutual regulation of facilitates chromatin transcription (FACT) subunits on both mRNA and protein levels in human cells

Alfiya Safina, Henry Garcia, Mairead Commane, Olga Guryanova, Seamus Degan, Kateryna Kolesnikova, Katerina V Gurova

Cell Cycle. 2013 Aug 1; 12(15): 2423–2434. Published online 2013 Jun 28. doi: 10.4161/cc.25452

PMCID:: PMC3841321

Abstract Article PDF–1.6M

Select item 145851910.

Modulation of nucleosome-binding activity of FACT by poly(ADP-ribosyl)ation

Jing-Yi Huang, Wei-Hao Chen, Ya-Ling Chang, Hsiao-Ting Wang, Wan-ting Chuang, Sheng-Chung Lee

Nucleic Acids Res. 2006; 34(8): 2398–2407. Published online 2006 May 8. doi: 10.1093/nar/gkl241

PMCID:: PMC1458519

Abstract Article PDF–385K

Select item 648654711.

FACT subunit Spt16 controls UVSSA recruitment to lesion-stalled RNA Pol II and stimulates TC-NER

Franziska Wienholz, Di Zhou, Yasemin Turkyilmaz, Petra Schwertman, Maria Tresini, Alex Pines, Marvin van Toorn, Karel Bezstarosti, Jeroen A A Demmers, Jurgen A Marteijn

Nucleic Acids Res. 2019 May 7; 47(8): 4011–4025. Published online 2019 Feb 4. doi: 10.1093/nar/gkz055

PMCID:: PMC6486547

Abstract Article PDF–2.8M

Select item 474298012.

Chromatin remodeller SMARCA4 recruits topoisomerase 1 and suppresses transcription-associated genomic instability

Afzal Husain, Nasim A. Begum, Takako Taniguchi, Hisaaki Taniguchi, Maki Kobayashi, Tasuku Honjo

Nat Commun. 2016; 7: 10549. Published online 2016 Feb 4. doi: 10.1038/ncomms10549

PMCID:: PMC4742980

Abstract Article PDF–3.1M

Select item 634488113.

The OTUD5–UBR5 complex regulates FACT-mediated transcription at damaged chromatin

Angelo de Vivo, Anthony Sanchez, Jose Yegres, Jeonghyeon Kim, Sylvia Emly, Younghoon Kee

Nucleic Acids Res. 2019 Jan 25; 47(2): 729–746. Published online 2018 Dec 1. doi: 10.1093/nar/gky1219

PMCID:: PMC6344881

Abstract Article PDF–14M

Select item 292325914.

Transcription through the HIV-1 nucleosomes: Effects of the PBAF complex in Tat activated transcription

Rebecca Easley, Lawrence Carpio, Luke Dannenberg, Soyun Choi, Dowser Alani, Rachel Van Duyne, Irene Guendel, Zachary Klase, Emmanuel Agbottah, Kylene Kehn-Hall, Fatah Kashanchi

Virology. Author manuscript; available in PMC 2011 Sep 30.

Published in final edited form as: Virology. 2010 Sep 30; 405(2): 322–333. doi: 10.1016/j.virol.2010.06.009

PMCID:: PMC2923259

Abstract Article PDF–1.0M

Select item 156036815.

Functional cooperation between FACT and MCM helicase facilitates initiation of chromatin DNA replication

Bertrand Chin-Ming Tan, Cheng-Ting Chien, Susumu Hirose, Sheng-Chung Lee

EMBO J. 2006 Sep 6; 25(17): 3975–3985. Published online 2006 Aug 10. doi: 10.1038/sj.emboj.7601271

PMCID:: PMC1560368

Abstract Article PDF–497K

Select item 232725616.

Histone H2A Monoubiquitination Represses Transcription by Inhibiting RNA Polymerase II Transcriptional Elongation

Wenlai Zhou, Ping Zhu, Jianxun Wang, Gabriel Pascual, Kenneth A. Ohgi, Jean Lozach, Christopher K. Glass, Michael G. Rosenfeld

Mol Cell. Author manuscript; available in PMC 2008 Apr 22.

Published in final edited form as: Mol Cell. 2008 Jan 18; 29(1): 69–80. doi: 10.1016/j.molcel.2007.11.002

PMCID:: PMC2327256

Abstract Article PDF–1.2M

Select item 625867317.

TRIM28 protects TRIM24 from SPOP-mediated degradation and promotes prostate cancer progression

Ka-wing Fong, Jonathan C. Zhao, Bing Song, Bin Zheng, Jindan Yu

Nat Commun. 2018; 9: 5007. Published online 2018 Nov 27. doi: 10.1038/s41467-018-07475-5

PMCID:: PMC6258673

Abstract Article PDF–3.1M

Select item 313556518.

Concordant and opposite roles of DNA-PK and the "facilitator of chromatin transcription" (FACT) in DNA repair, apoptosis and necrosis after cisplatin

Janna Sand-Dejmek, Guillaume Adelmant, Bijan Sobhian, Anne S Calkins, Jarrod Marto, Dirk J Iglehart, Jean-Bernard Lazaro

Mol Cancer. 2011; 10: 74. Published online 2011 Jun 16. doi: 10.1186/1476-4598-10-74

PMCID:: PMC3135565

Abstract Article PDF–1011K

Select item 300623719.

A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability

Brenda C. O’Connell, Britt Adamson, John R. Lydeard, Mathew E. Sowa, Alberto Ciccia, Andrea L Bredemeyer, Michael Schlabach, Steven P. Gygi, Stephen J. Elledge, J. Wade Harper

Mol Cell. Author manuscript; available in PMC 2011 Nov 24.

Published in final edited form as: Mol Cell. 2010 Nov 24; 40(4): 645–657. Published online 2010 Nov 4. doi: 10.1016/j.molcel.2010.10.022