Volume 121(19); 2024 May 7

Articles from this journal are generally available in PMC after a 6-month delay (embargo); however, the delay may vary at the discretion of the publisher.

This Week in PNAS

In This Issue

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): eiti1924121. Published online 2024 May 7. doi: 10.1073/iti1924121

PMCID:: PMC11087763

Currently embargoed: Free in PMC on Nov 7, 2024

Letters

Continuity of the Sangdanlin Paleocene section and rejection of a large Greater India in the Early Cretaceous

Wentao Huang, Eduardo Garzanti, Theodore C. Moore, Paul Kapp, Peter G. DeCelles, Shanshan Niu

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2402456121. Published online 2024 Apr 29. doi: 10.1073/pnas.2402456121

PMCID:: PMC11087756

Article PDF–206K

Reply to Huang et al.: Debunking the Sangdanlin myth

Jun Meng, Stuart A. Gilder, Xiaodong Tan, Xin Li, Yalin Li, Hui Luo, Noritoshi Suzuki, Zihao Wang, Yuchen Chi, Chunyang Zhang, Chengshan Wang

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2403014121. Published online 2024 Apr 29. doi: 10.1073/pnas.2403014121

PMCID:: PMC11087764

Article PDF–153K

Bonding in tellurides

Tae Hoon Lee, Stephen Elliott

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2403308121. Published online 2024 Apr 29. doi: 10.1073/pnas.2403308121

PMCID:: PMC11087767

Article PDF–134K

Reply to Lee and Elliott: Changes of bonding upon crystallization in phase change materials

Jean-Yves Raty, Christophe Bichara, Carl-Friedrich Schön, Carlo Gatti, Matthias Wuttig

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2405294121. Published online 2024 Apr 29. doi: 10.1073/pnas.2405294121

PMCID:: PMC11087775

Article PDF–359K

Opinion

Community Review Boards offer a path to research equity

Cameron John Sabet, Simar S. Bajaj, Fatima Cody Stanford

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2320334121. Published online 2024 May 1. doi: 10.1073/pnas.2320334121

PMCID:: PMC11087801

Article PDF–733K

QnAs

QnAs with Katherine Freese

Paul Gabrielsen

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2407157121. Published online 2024 May 2. doi: 10.1073/pnas.2407157121

PMCID:: PMC11087743

Currently embargoed: Free in PMC on Nov 2, 2024; PubMed

Retrospective

Arno Allan Penzias (1933–2024): A visionary explorer of the Universe

K. I. Kellermann

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2405969121. Published online 2024 Apr 30. doi: 10.1073/pnas.2405969121

PMCID:: PMC11087769

Article PDF–806K

Commentaries

Coming of age in venom research

Ricardo C. Rodríguez de la Vega

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2405708121. Published online 2024 Apr 30. doi: 10.1073/pnas.2405708121

PMCID:: PMC11087774

Currently embargoed: Free in PMC on Oct 30, 2024; PubMed

Three’s a crowd: Saccharibacteria episymbiosis modulates phage predation of host bacteria

Richard J. Lamont

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2405822121. Published online 2024 Apr 29. doi: 10.1073/pnas.2405822121

PMCID:: PMC11087802

Currently embargoed: Free in PMC on Oct 29, 2024; PubMed

Perspective

Developing a predictive science of the biosphere requires the integration of scientific cultures

Brian J. Enquist, Christopher P. Kempes, Geoffrey B. West

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2209196121. Published online 2024 Apr 19. doi: 10.1073/pnas.2209196121

PMCID:: PMC11087787

Article PDF–767K

Physical Sciences

Applied Mathematics

Bridging the gap between models based on ordinary, delayed, and fractional differentials equations through integral kernels

Noemi Zeraick Monteiro, Rodrigo Weber dos Santos, Sandro Rodrigues Mazorche

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2322424121. Published online 2024 May 2. doi: 10.1073/pnas.2322424121

PMCID:: PMC11087811

Currently embargoed: Free in PMC on Nov 2, 2024; PubMed

Applied Physical Sciences

Nonreciprocity and odd viscosity in chiral active fluids

Tomer Markovich, Tom C. Lubensky

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2219385121. Published online 2024 May 3. doi: 10.1073/pnas.2219385121

PMCID:: PMC11087745

Currently embargoed: Free in PMC on Nov 3, 2024; PubMed

Effect of skull morphology on fox snow diving

Jisoo Yuk, Anupam Pandey, Leena Park, William E. Bemis, Sunghwan Jung

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2321179121. Published online 2024 Apr 29. doi: 10.1073/pnas.2321179121

PMCID:: PMC11087747

Currently embargoed: Free in PMC on Oct 29, 2024; PubMed

Biophysics and Computational Biology

Proteolytic stability and aggregation in a key metabolic enzyme of bacteria

Dan Pollack, Takashi Nozoe, Edo Kussell

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2301458121. Published online 2024 Apr 29. doi: 10.1073/pnas.2301458121

PMCID:: PMC11087809

Currently embargoed: Free in PMC on Oct 29, 2024; PubMed

Interdependence of cellular and network properties in respiratory rhythm generation

Ryan S. Phillips, Nathan A. Baertsch

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2318757121. Published online 2024 May 1. doi: 10.1073/pnas.2318757121

PMCID:: PMC11087776

Article PDF–15M

Structural insights into human MHC-II association with invariant chain

Nan Wang, Deepa Waghray, Nathanael A. Caveney, Kevin M. Jude, K. Christopher Garcia

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2403031121. Published online 2024 Apr 30. doi: 10.1073/pnas.2403031121

PMCID:: PMC11087810

Article PDF–9.0M

Chemistry

Catalysis driven by an amyloid–substrate complex

Taka Sawazaki, Daisuke Sasaki, Youhei Sohma

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2314704121. Published online 2024 May 1. doi: 10.1073/pnas.2314704121

PMCID:: PMC11087796

Currently embargoed: Free in PMC on Nov 1, 2024; PubMed

Tailoring atomic chemistry to refine reaction pathway for the most enhancement by magnetization in water oxidation

Tianze Wu, Jingjie Ge, Qian Wu, Xiao Ren, Fanxu Meng, Jiarui Wang, Shibo Xi, Xin Wang, Kamal Elouarzaki, Adrian Fisher, Zhichuan J. Xu

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2318652121. Published online 2024 Apr 30. doi: 10.1073/pnas.2318652121

PMCID:: PMC11087795

Currently embargoed: Free in PMC on Oct 30, 2024; PubMed

Engineering tertiary chirality in helical biopolymers

Jordan Janowski, Van A. B. Pham, Simon Vecchioni, Karol Woloszyn, Brandon Lu, Yijia Zou, Betel Erkalo, Lara Perren, Joe Rueb, Jesse Madnick, Chengde Mao, Masahico Saito, Yoel P. Ohayon, Nataša Jonoska, Ruojie Sha

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2321992121. Published online 2024 Apr 29. doi: 10.1073/pnas.2321992121

PMCID:: PMC11087804

Currently embargoed: Free in PMC on Oct 29, 2024; PubMed

Sum rule comparison of narrowband and broadband sum frequency generation spectra and comparison with theory

Kai Niu, Hong-fei Wang, Rudolph A. Marcus

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2402550121. Published online 2024 May 1. doi: 10.1073/pnas.2402550121

PMCID:: PMC11087750

Article PDF–1.1M

Earth, Atmospheric, and Planetary Sciences

3D intrusions transport active surface microbial assemblages to the dark ocean

Mara A. Freilich, Camille Poirier, Mathieu Dever, Eva Alou-Font, John Allen, Andrea Cabornero, Lisa Sudek, Chang Jae Choi, Simón Ruiz, Ananda Pascual, J. Thomas Farrar, T. M. Shaun Johnston, Eric A. D’Asaro, Alexandra Z. Worden, Amala Mahadevan

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2319937121. Published online 2024 May 2. doi: 10.1073/pnas.2319937121

PMCID:: PMC11087786

Currently embargoed: Free in PMC on Nov 2, 2024; PubMed

Radiocarbon chronology of Iron Age Jerusalem reveals calibration offsets and architectural developments

Johanna Regev, Yuval Gadot, Joe Uziel, Ortal Chalaf, Yiftah Shalev, Helena Roth, Nitsan Shalom, Nahshon Szanton, Efrat Bocher, Charlotte L. Pearson, David M. Brown, Eugenia Mintz, Lior Regev, Elisabetta Boaretto

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2321024121. Published online 2024 Apr 29. doi: 10.1073/pnas.2321024121

PMCID:: PMC11087761

Currently embargoed: Free in PMC on Oct 29, 2024; PubMed

Engineering

Neuronal innervation regulates the secretion of neurotrophic myokines and exosomes from skeletal muscle

Kai-Yu Huang, Gaurav Upadhyay, Yujin Ahn, Masayoshoi Sakakura, Gelson J. Pagan-Diaz, Younghak Cho, Amanda C. Weiss, Chen Huang, Jennifer W. Mitchell, Jiahui Li, Yanqi Tan, Yu-Heng Deng, Austin Ellis-Mohr, Zhi Dou, Xiaotain Zhang, Sehong Kang, Qian Chen, Jonathan V. Sweedler, Sung Gap Im, Rashid Bashir, Hee Jung Chung, Gabriel Popescu, Martha U. Gillette, Mattia Gazzola, Hyunjoon Kong

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2313590121. Published online 2024 Apr 29. doi: 10.1073/pnas.2313590121

PMCID:: PMC11087749

Currently embargoed: Free in PMC on Oct 29, 2024; PubMed

Statistics

Robust inference of causality in high-dimensional dynamical processes from the Information Imbalance of distance ranks

Vittorio Del Tatto, Gianfranco Fortunato, Domenica Bueti, Alessandro Laio

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2317256121. Published online 2024 Apr 30. doi: 10.1073/pnas.2317256121

PMCID:: PMC11087807

Currently embargoed: Free in PMC on Oct 30, 2024; PubMed

Social Sciences

Political Sciences

The impact of US–China tensions on US science: Evidence from the NIH investigations

Ruixue Jia, Margaret E. Roberts, Ye Wang, Eddie Yang

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2301436121. Published online 2024 Apr 30. doi: 10.1073/pnas.2301436121

PMCID:: PMC11087765

Article PDF–2.0M

The politics of allyship: Multiethnic coalitions and mass attitudes toward protest

Devorah Manekin, Tamar Mitts, Yael Zeira

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2314653121. Published online 2024 May 2. doi: 10.1073/pnas.2314653121

PMCID:: PMC11087770

Currently embargoed: Free in PMC on Nov 2, 2024; PubMed

Correcting misperceptions of the material benefits associated with union membership increases Americans’ interest in joining unions

Jonne Kamphorst, Robb Willer

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2321025121. Published online 2024 Apr 29. doi: 10.1073/pnas.2321025121

PMCID:: PMC11087758

Article PDF–8.9M

Psychological and Cognitive Sciences

Localizing somatic symptoms associated with childhood maltreatment

Ethan G. Dutcher, Sara C. Verosky, Wendy Berry Mendes, Stefanie E. Mayer

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2318128121. Published online 2024 Apr 30. doi: 10.1073/pnas.2318128121

PMCID:: PMC11087768

Currently embargoed: Free in PMC on Oct 30, 2024; PubMed

Social Science

Indirect reciprocity undermines indirect reciprocity destabilizing large-scale cooperation

Eric Schnell, Michael Muthukrishna

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2322072121. Published online 2024 Apr 29. doi: 10.1073/pnas.2322072121

PMCID:: PMC11087788

Article PDF–880K

Biological Sciences

Agricultural Sciences

UDP-glycosyltransferases act as key determinants of host plant range in generalist and specialist Spodoptera species

Huidong Wang, Jing Song, Benjamin J. Hunt, Kairan Zuo, Huiru Zhou, Angela Hayward, Bingbing Li, Yajuan Xiao, Xing Geng, Chris Bass, Shutang Zhou

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2402045121. Published online 2024 Apr 29. doi: 10.1073/pnas.2402045121

PMCID:: PMC11087754

Article PDF–4.7M

Applied Biological Sciences

Tailored UPRE2 variants for dynamic gene regulation in yeast

Chufan Xiao, Xiufang Liu, Yuyang Pan, Yanling Li, Ling Qin, Zhibo Yan, Yunzi Feng, Mouming Zhao, Mingtao Huang

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2315729121. Published online 2024 Apr 30. doi: 10.1073/pnas.2315729121

PMCID:: PMC11087760

Article PDF–1.6M

Engineered polymer nanoparticles as artificial chaperones facilitating the selective refolding of denatured enzymes

Yan Li, Deping Yin, Sang Yup Lee, Yongqin Lv

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2403049121. Published online 2024 May 1. doi: 10.1073/pnas.2403049121

PMCID:: PMC11087784

Currently embargoed: Free in PMC on Nov 1, 2024; PubMed

Biochemistry

A general approach for selection of epitope-directed binders to proteins

Jie Zhou, Chau Q. Le, Yun Zhang, James A. Wells

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2317307121. Published online 2024 Apr 29. doi: 10.1073/pnas.2317307121

PMCID:: PMC11087759

Article PDF–5.1M

Extrachromosomal telomere DNA derived from excessive strand displacements

Junyeop Lee, Jina Lee, Eric J. Sohn, Angelo Taglialatela, Roderick J. O’Sullivan, Alberto Ciccia, Jaewon Min

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2318438121. Published online 2024 May 2. doi: 10.1073/pnas.2318438121

PMCID:: PMC11087782

Currently embargoed: Free in PMC on Nov 2, 2024; PubMed

The tRNA^Val half: A strong endogenous Toll-like receptor 7 ligand with a 5′-terminal universal sequence signature

Kamlesh Pawar, Takuya Kawamura, Yohei Kirino

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2319569121. Published online 2024 Apr 29. doi: 10.1073/pnas.2319569121

PMCID:: PMC11087793

Article PDF–4.0M

Biophysics and Computational Biology

Incomplete-penetrant hypertrophic cardiomyopathy MYH7 G256E mutation causes hypercontractility and elevated mitochondrial respiration

Soah Lee, Alison S. Vander Roest, Cheavar A. Blair, Kerry Kao, Samantha B. Bremner, Matthew C. Childers, Divya Pathak, Paul Heinrich, Daniel Lee, Orlando Chirikian, Saffie E. Mohran, Brock Roberts, Jacqueline E. Smith, James W. Jahng, David T. Paik, Joseph C. Wu, Ruwanthi N. Gunawardane, Kathleen M. Ruppel, David L. Mack, Beth L. Pruitt, Michael Regnier, Sean M. Wu, James A. Spudich, Daniel Bernstein

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2318413121. Published online 2024 Apr 29. doi: 10.1073/pnas.2318413121

PMCID:: PMC11087781

Currently embargoed: Free in PMC on Oct 29, 2024; PubMed

Influence of lipid bilayer on the structure of the muscle-type nicotinic acetylcholine receptor

Nigel Unwin

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2319913121. Published online 2024 Apr 29. doi: 10.1073/pnas.2319913121

PMCID:: PMC11087746

Article PDF–1.4M

Discovering optimal kinetic pathways for self-assembly using automatic differentiation

Adip Jhaveri, Spencer Loggia, Yian Qian, Margaret E. Johnson

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2403384121. Published online 2024 May 1. doi: 10.1073/pnas.2403384121

PMCID:: PMC11087789

Currently embargoed: Free in PMC on Nov 1, 2024; PubMed

Cell Biology

β-catenin turnover is regulated by Nek10-mediated tyrosine phosphorylation in A549 lung adenocarcinoma cells

Previn Dutt, Nasir Haider, Samar Mouaaz, Lauren Podmore, Vuk Stambolic

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2300606121. Published online 2024 Apr 29. doi: 10.1073/pnas.2300606121

PMCID:: PMC11087748

Article PDF–1.6M

OTUB2 silencing promotes ovarian cancer via mitochondrial metabolic reprogramming and can be synthetically targeted by CA9 inhibition

Yabing Nan, Xiaowei Wu, Qingyu Luo, Wan Chang, Pengfei Zhao, Lingqiang Zhang, Zhihua Liu

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2315348121. Published online 2024 May 3. doi: 10.1073/pnas.2315348121

PMCID:: PMC11087800

Currently embargoed: Free in PMC on Nov 3, 2024; PubMed

An aldehyde-crosslinking mitochondrial probe for STED imaging in fixed cells

Jingting Chen, Till Stephan, Felix Gaedke, Tianyan Liu, Yiyan Li, Astrid Schauss, Peng Chen, Veronika Wulff, Stefan Jakobs, Christian Jüngst, Zhixing Chen

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2317703121. Published online 2024 Apr 30. doi: 10.1073/pnas.2317703121

PMCID:: PMC11087744

Article PDF–5.5M

Transient Zn²⁺ deficiency induces replication stress and compromises daughter cell proliferation

Samuel E. Holtzen, Elnaz Navid, Joseph D. Kainov, Amy E. Palmer

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2321216121. Published online 2024 Apr 30. doi: 10.1073/pnas.2321216121

PMCID:: PMC11087780

Currently embargoed: Free in PMC on Oct 30, 2024; PubMed

Myospreader improves gene editing in skeletal muscle by myonuclear propagation

Kiril K. Poukalov, M. Carmen Valero, Derek R. Muscato, Leanne M. Adams, Heejae Chun, Young il Lee, Nadja S. Andrade, Zane Zeier, H. Lee Sweeney, Eric T. Wang

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2321438121. Published online 2024 Apr 30. doi: 10.1073/pnas.2321438121

PMCID:: PMC11087771

Currently embargoed: Free in PMC on Oct 30, 2024; PubMed

Functional overlap between the mammalian Sar1a and Sar1b paralogs in vivo

Vi T. Tang, Jie Xiang, Zhimin Chen, Joseph McCormick, Prabhodh S. Abbineni, Xiao-Wei Chen, Mark Hoenerhoff, Brian T. Emmer, Rami Khoriaty, Jiandie D. Lin, David Ginsburg

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2322164121. Published online 2024 Apr 30. doi: 10.1073/pnas.2322164121

PMCID:: PMC11087783

Currently embargoed: Free in PMC on Oct 30, 2024; PubMed

Developmental Biology

A time-resolved single-cell roadmap of the logic driving anterior neural crest diversification from neural border to migration stages

Aleksandr Kotov, Subham Seal, Mansour Alkobtawi, Vincent Kappès, Sofia Medina Ruiz, Hugo Arbès, Richard M. Harland, Leonid Peshkin, Anne H. Monsoro-Burq

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2311685121. Published online 2024 Apr 29. doi: 10.1073/pnas.2311685121

PMCID:: PMC11087755

Currently embargoed: Free in PMC on Oct 29, 2024; PubMed

BRCA1 safeguards genome integrity by activating chromosome asynapsis checkpoint to eliminate recombination-defective oocytes

Long Bai, Peng Li, Yu Xiang, Xiaofei Jiao, Jiyuan Chen, Licun Song, Zhongyang Liang, Yidan Liu, Yimin Zhu, Lin-Yu Lu

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2401386121. Published online 2024 May 2. doi: 10.1073/pnas.2401386121

PMCID:: PMC11087798

Article PDF–10M

Ecology

Predicting resilience of migratory birds to environmental change

Simeon Lisovski, Bethany J. Hoye, Jesse R. Conklin, Phil F. Battley, Richard A. Fuller, Ken B. Gosbell, Marcel Klaassen, Chengfa Benjamin Lee, Nicholas J. Murray, Silke Bauer

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2311146121. Published online 2024 Apr 22. doi: 10.1073/pnas.2311146121

PMCID:: PMC11087779

Currently embargoed: Free in PMC on Oct 22, 2024; PubMed

Evolution

Detecting inbreeding depression in structured populations

Eléonore Lavanchy, Bruce S. Weir, Jérôme Goudet

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2315780121. Published online 2024 Apr 30. doi: 10.1073/pnas.2315780121

PMCID:: PMC11087799

Article PDF–1.6M

Genetics

Species-wide quantitative transcriptomes and proteomes reveal distinct genetic control of gene expression variation in yeast

Elie Marcel Teyssonnière, Pauline Trébulle, Julia Muenzner, Victor Loegler, Daniela Ludwig, Fatma Amari, Michael Mülleder, Anne Friedrich, Jing Hou, Markus Ralser, Joseph Schacherer

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2319211121. Published online 2024 May 2. doi: 10.1073/pnas.2319211121

PMCID:: PMC11087752

Article PDF–22M

Immunology and Inflammation

CCR3-dependent eosinophil recruitment is regulated by sialyltransferase ST3Gal-IV

Roland Immler, Katrin Nussbaumer, Axel Doerner, Omar El Bounkari, Silke Huber, Janine Abisch, Matteo Napoli, Sarah Schmidt, Andreas Margraf, Monika Pruenster, Ina Rohwedder, Baerbel Lange-Sperandio, Marcus A. Mall, Renske de Jong, Caspar Ohnmacht, Juergen Bernhagen, David Voehringer, Jamey D. Marth, David Frommhold, Markus Sperandio

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2319057121. Published online 2024 Apr 30. doi: 10.1073/pnas.2319057121

PMCID:: PMC11087806

Currently embargoed: Free in PMC on Oct 30, 2024; PubMed

Deficiency of IL-22–binding protein enhances the ability of the gut microbiota to protect against enteric pathogens

José L. Fachi, Blanda Di Luccia, Susan Gilfillan, Hao-Wei Chang, Christina Song, Jiye Cheng, Marina Cella, Marco Aurelio Vinolo, Jeffrey I. Gordon, Marco Colonna

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2321836121. Published online 2024 Apr 30. doi: 10.1073/pnas.2321836121

PMCID:: PMC11087805

Currently embargoed: Free in PMC on Oct 30, 2024; PubMed

The IL-17 pathway intertwines with neurotrophin and TLR/IL-1R pathways since its domain shuffling origin

Shenghui Chen, Huiping Fan, Chenrui Ran, Yun Hong, Huixiong Feng, Zirui Yue, Hao Zhang, Pierre Pontarotti, Anlong Xu, Shengfeng Huang

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2400903121. Published online 2024 Apr 29. doi: 10.1073/pnas.2400903121

PMCID:: PMC11087794

Currently embargoed: Free in PMC on Oct 29, 2024; PubMed

Medical Sciences

Impact of repeated blast exposure on active-duty United States Special Operations Forces

Natalie Gilmore, Chieh-En J. Tseng, Chiara Maffei, Samantha L. Tromly, Katryna B. Deary, Isabella R. McKinney, Jessica N. Kelemen, Brian C. Healy, Collin G. Hu, Gabriel Ramos-Llordén, Maryam Masood, Ryan J. Cali, Jennifer Guo, Heather G. Belanger, Eveline F. Yao, Timothy Baxter, Bruce Fischl, Andrea S. Foulkes, Jonathan R. Polimeni, Bruce R. Rosen, Daniel P. Perl, Jacob M. Hooker, Nicole R. Zürcher, Susie Y. Huang, W. Taylor Kimberly, Douglas N. Greve, Christine L. Mac Donald, Kristen Dams-O’Connor, Yelena G. Bodien, Brian L. Edlow

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2313568121. Published online 2024 Apr 22. doi: 10.1073/pnas.2313568121

PMCID:: PMC11087753

Article PDF–2.1M

Genetic and phenotypic profiling of single living circulating tumor cells from patients with microfluidics

Zaizai Dong, Yusen Wang, Gaolian Xu, Bing Liu, Yang Wang, Julien Reboud, Pawel Jajesniak, Shi Yan, Pingchuan Ma, Feng Liu, Yuhao Zhou, Zhiyuan Jin, Kuan Yang, Zhaocun Huang, Minglei Zhuo, Bo Jia, Jian Fang, Panpan Zhang, Nan Wu, Mingzhu Yang, Jonathan M. Cooper, Lingqian Chang

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2315168121. Published online 2024 Apr 29. doi: 10.1073/pnas.2315168121

PMCID:: PMC11087790

Currently embargoed: Free in PMC on Oct 29, 2024; PubMed

An HLA-E-targeted TCR bispecific molecule redirects T cell immunity against Mycobacterium tuberculosis

Rachel L. Paterson, Marco P. La Manna, Victoria Arena De Souza, Andrew Walker, Dawn Gibbs-Howe, Rakesh Kulkarni, Joannah R. Fergusson, Nitha Charles Mulakkal, Mauro Monteiro, Wilawan Bunjobpol, Marcin Dembek, Magdalena Martin-Urdiroz, Tressan Grant, Claire Barber, Diana J. Garay-Baquero, Liku Bekele Tezera, David Lowne, Camille Britton-Rivet, Robert Pengelly, Natalia Chepisiuk, Praveen K. Singh, Amanda P. Woon, Alex S. Powlesland, Michelle L. McCully, Nadia Caccamo, Mariolina Salio, Giusto Davide Badami, Lucy Dorrell, Andrew Knox, Ross Robinson, Paul Elkington, Francesco Dieli, Marco Lepore, Sarah Leonard, Luis F. Godinho

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2318003121. Published online 2024 May 1. doi: 10.1073/pnas.2318003121

PMCID:: PMC11087797

Article PDF–4.9M

Development of porcine skeletal muscle extracellular matrix–derived hydrogels with improved properties and low immunogenicity

Mohammed A. Barajaa, Takayoshi Otsuka, Debolina Ghosh, Ho-Man Kan, Cato T. Laurencin

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2322822121. Published online 2024 Apr 30. doi: 10.1073/pnas.2322822121

PMCID:: PMC11087813

Article PDF–6.4M

Microbiology

Monocyte to macrophage differentiation and changes in cellular redox homeostasis promote cell type-specific HIV latency reactivation

Alexandra Blanco, Robert A. Coronado, Neha Arun, Kelly Ma, Roy D. Dar, Collin Kieffer

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2313823121. Published online 2024 Apr 29. doi: 10.1073/pnas.2313823121

PMCID:: PMC11087762

Article PDF–4.4M

Frequent nonhomologous replacement of replicative helicase loaders by viruses in Vibrionaceae

Kento Tominaga, Shogo Ozaki, Shohei Sato, Tsutomu Katayama, Yuki Nishimura, Kimiho Omae, Wataru Iwasaki

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2317954121. Published online 2024 Apr 29. doi: 10.1073/pnas.2317954121

PMCID:: PMC11087808

Article PDF–9.9M

Identification and epidemiological study of an uncultured flavivirus from ticks using viral metagenomics and pseudoinfectious viral particles

Daisuke Kobayashi, Yusuke Inoue, Ryosuke Suzuki, Mami Matsuda, Hiroshi Shimoda, Astri Nur Faizah, Yoshihiro Kaku, Keita Ishijima, Yudai Kuroda, Kango Tatemoto, Milagros Virhuez-Mendoza, Michiko Harada, Ayano Nishino, Mizue Inumaru, Kenzo Yonemitsu, Ryusei Kuwata, Ai Takano, Mamoru Watanabe, Yukiko Higa, Kyoko Sawabe, Ken Maeda, Haruhiko Isawa

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2319400121. Published online 2024 Apr 30. doi: 10.1073/pnas.2319400121

PMCID:: PMC11087778

Currently embargoed: Free in PMC on Oct 30, 2024; PubMed

An essential and highly selective protein import pathway encoded by nucleus-forming phage

Chase J. Morgan, Eray Enustun, Emily G. Armbruster, Erica A. Birkholz, Amy Prichard, Taylor Forman, Ann Aindow, Wichanan Wannasrichan, Sela Peters, Koe Inlow, Isabelle L. Shepherd, Alma Razavilar, Vorrapon Chaikeeratisak, Benjamin A. Adler, Brady F. Cress, Jennifer A. Doudna, Kit Pogliano, Elizabeth Villa, Kevin D. Corbett, Joe Pogliano

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2321190121. Published online 2024 Apr 30. doi: 10.1073/pnas.2321190121

PMCID:: PMC11087766

Article PDF–7.2M

The HSV-1 pUL37 protein promotes cell invasion by regulating the kinesin-1 motor

DongHo Kim, Michael A. Cianfrocco, Kristen J. Verhey, Gregory A. Smith

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2401341121. Published online 2024 May 2. doi: 10.1073/pnas.2401341121

PMCID:: PMC11087751

Currently embargoed: Free in PMC on Nov 2, 2024; PubMed

Neuroscience

Human mutations in high-confidence Tourette disorder genes affect sensorimotor behavior, reward learning, and striatal dopamine in mice

Cara Nasello, Lauren A. Poppi, Junbing Wu, Tess F. Kowalski, Joshua K. Thackray, Riley Wang, Angelina Persaud, Mariam Mahboob, Sherry Lin, Rodna Spaseska, C. K. Johnson, Derek Gordon, Fadel Tissir, Gary A. Heiman, Jay A. Tischfield, Miriam Bocarsly, Max A. Tischfield

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2307156121. Published online 2024 Apr 29. doi: 10.1073/pnas.2307156121

PMCID:: PMC11087812

Currently embargoed: Free in PMC on Oct 29, 2024; PubMed

Voltage-induced calcium release in Caenorhabditis elegans body muscles

Luna Gao, Evan Ardiel, Stephen Nurrish, Joshua M. Kaplan

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2317753121. Published online 2024 Apr 30. doi: 10.1073/pnas.2317753121

PMCID:: PMC11087772

Article PDF–5.4M

Pharmacology

Dermonecrosis caused by a spitting cobra snakebite results from toxin potentiation and is prevented by the repurposed drug varespladib

Keirah E. Bartlett, Steven R. Hall, Sean A. Rasmussen, Edouard Crittenden, Charlotte A. Dawson, Laura-Oana Albulescu, William Laprade, Robert A. Harrison, Anthony J. Saviola, Cassandra M. Modahl, Timothy P. Jenkins, Mark C. Wilkinson, José María Gutiérrez, Nicholas R. Casewell

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2315597121. Published online 2024 Apr 30. doi: 10.1073/pnas.2315597121

PMCID:: PMC11087757

Article PDF–3.9M

Physiology

The thermoneutral zone in women takes an “arctic” shift compared to men

Robert J. Brychta, Suzanne McGehee, Shan Huang, Brooks P. Leitner, Courtney J. Duckworth, Laura A. Fletcher, Katherine Kim, Thomas M. Cassimatis, Nikita S. Israni, Hannah J. Lea, Taylor N. Lentz, Anne E. Pierce, Alex Jiang, Samuel R. LaMunion, Reed J. Thomas, Asuka Ishihara, Amber B. Courville, Shanna B. Yang, Marc L. Reitman, Aaron M. Cypess, Kong Y. Chen

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2311116121. Published online 2024 Apr 29. doi: 10.1073/pnas.2311116121

PMCID:: PMC11087792

Currently embargoed: Free in PMC on Oct 29, 2024; PubMed

Understanding stoichiometric constraints on growth using resource use efficiency imbalances

Clay Prater, Tin Phan, James J. Elser, Punidan D. Jeyasingh

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2319022121. Published online 2024 Apr 29. doi: 10.1073/pnas.2319022121

PMCID:: PMC11087777

Currently embargoed: Free in PMC on Oct 29, 2024; PubMed

Identification of potent pan-ephrin receptor kinase inhibitors using DNA-encoded chemistry technology

Chandrashekhar Madasu, Zian Liao, Sydney E. Parks, Kiran L. Sharma, Kurt M. Bohren, Qiuji Ye, Feng Li, Murugesan Palaniappan, Zhi Tan, Fei Yuan, Chad J. Creighton, Suni Tang, Ramya P. Masand, Xiaoming Guan, Damian W. Young, Diana Monsivais, Martin M. Matzuk

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2322934121. Published online 2024 May 3. doi: 10.1073/pnas.2322934121

PMCID:: PMC11087803

Currently embargoed: Free in PMC on Nov 3, 2024; PubMed

Plant Biology

Strigolactones promote flowering by inducing the miR319-LA-SFT module in tomato

Ivan Visentin, Leticia Frizzo Ferigolo, Giulia Russo, Paolo Korwin Krukowski, Caterina Capezzali, Danuše Tarkowská, Francesco Gresta, Eleonora Deva, Fabio Tebaldi Silveira Nogueira, Andrea Schubert, Francesca Cardinale

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2316371121. Published online 2024 May 3. doi: 10.1073/pnas.2316371121

PMCID:: PMC11087791

Currently embargoed: Free in PMC on Nov 3, 2024; PubMed

DELLA proteins recruit the Mediator complex subunit MED15 to coactivate transcription in land plants

Jorge Hernández-García, Antonio Serrano-Mislata, María Lozano-Quiles, Cristina Úrbez, María A. Nohales, Noel Blanco-Touriñán, Huadong Peng, Rodrigo Ledesma-Amaro, Miguel A. Blázquez

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2319163121. Published online 2024 May 2. doi: 10.1073/pnas.2319163121

PMCID:: PMC11087773

Currently embargoed: Free in PMC on Nov 2, 2024; PubMed

Correction

Correction for Gilbert, Complex deep-sea expeditions try to size up seabed mining impacts

Proc Natl Acad Sci U S A. 2024 May 7; 121(19): e2407244121. Published online 2024 May 1. doi: 10.1073/pnas.2407244121

Corrects:: Proc Natl Acad Sci U S A. 2024 Apr 9; 121(15): e2404667121.

PMCID:: PMC11087785

Correction PDF–68K

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