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Antifungal activity against Schizosaccharomyces pombe efflux-defective strain MJ-1682 assessed as inhibition of fungal growth by broth microdilution method
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed Citation
Antifungal activity against Schizosaccharomyces pombe assessed as fungal growth inhibition incubated for 18 hrs by absorbance based assay
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Antifungal activity against wild type fission yeast JY1 after 24 hrs by XTT assay
Antifungal activity against wild type fission yeast JY1 after 24 hrs by turbidity assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Antifungal activity against fission yeast harboring deltasts1/erg4 mutant after 24 hrs by turbidity assay
Antifungal activity against fission yeast harboring deltaerg5 mutant after 24 hrs by turbidity assay
Antifungal activity against fission yeast harboring deltaerg31/deltaerg32 mutant after 24 hrs by turbidity assay
Antifungal activity against fission yeast harboring deltaerg2 mutant after 24 hrs by turbidity assay
Antifungal activity against Schizosaccharomyces pombe after 18 to 20 hrs by microbroth dilution method
Assay data:10 Active, 16 Tested
Inhibition of Schizosaccharomyces pombe CK1
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Antimicrobial activity against Schizosaccharomyces pombe L972 h-
Assay data:1 Active, 8 Tested
Suppression of Cl-sensitive growth defect in Schizosaccharomyces pombe harboring h+leu1 ura4-D18 ppb1::ura4+ mutant assessed as colony formation at 100 uM measured after 3 days in presence of MgCl2 by disc filter paper
Assay data:21 Active, 24 Tested
Antifungal activity against Schizosaccharomyces pombe at 33.5 ug/ml after 24 to 48 hrs
Antifungal activity against wild type fission yeast JY1 assessed as accumulation of cell wall material at 0.25 uM after 2 hrs by cfw-dye based fluorescence microscopic analysis
Antifungal activity against wild type fission yeast JY1 assessed as accumulation of cell wall material at 0.5 uM after 2 hrs by cfw-dye based fluorescence microscopic analysis
Suppression of calcium-sensitive growth defect in calcineurin gene deleted Schizosaccharomyces pombe (h+ leu1 ura4-D18 ppb1::ura4+) at 100 uM after 3 days by filter paper disk assay in presence of 0.11 M MgCl2 in YPD medium
Assay data:4 Active, 6 Tested
Induction of calcium signaling pathway-mediated cell growth in ppb1-deficient Schizosaccharomyces pombe h+ leu1 ura4-D18 ppb1::ura4+ at 100 uM after 3 days by filter paper disc method in presence of MgCl2
Assay data:6 Active, 6 Tested
Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB
Assay data:3916 Active, 206 Activity ≤ 1 nM, 1830 Activity ≤ 1 µM, 3916 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB
Assay data:3598 Active, 421 Activity ≤ 1 nM, 2233 Activity ≤ 1 µM, 3598 Tested
Experimentally measured binding affinity data derived from PDB
Assay data:3073 Active, 3073 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
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