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Effective concentration for phenotypic endpoint in tadpoles
Assay data:1 Tested
SummaryPubMed Citation
Effective concentration for tadpole immobility after 5 min (slow recovery)
Effective concentration for tadpole immobility (less potent)
Effective concentration for rapid onset of reversible immobility (tadpole) at about 0.1 mM
Effective concentration for rapid immobilization of tadpole
Anesthetic potency, Concentration for loss of righting reflexes (LORR) in Xenopus tadpoles
Assay data:2 Active, 4 Tested
SummaryCompounds, ActivePubMed Citation
Compound was evaluated for blocking of depolarization induced by 30 uM AMPA in xenopus oocytes injected with rat brain m-RNA
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Compound was evaluated for blocking of depolarization induced by 3 uM NMDA in xenopus oocytes injected with rat brain m-RNA
Inhibition of currents generated by 50 uM kainate in Xenopus oocytes injected with rat brain mRNA
Assay data:13 Active, 12 Activity ≤ 1 µM, 13 Tested
Agonistic activity against melatonin of Xenopus melanophores
Assay data:26 Active, 6 Activity ≤ 1 µM, 32 Tested
Effective concentration for its agonist activity against melatonin of Xenopus melanophores
Assay data:11 Active, 1 Activity ≤ 1 nM, 10 Activity ≤ 1 µM, 11 Tested
Loss of swimming behavior in Xenopus laevis tadpole.
Assay data:16 Active, 3 Activity ≤ 1 µM, 16 Tested
Loss of righting reflex in Xenopus laevis tadpole.
Assay data:18 Active, 8 Activity ≤ 1 µM, 18 Tested
Inhibitory concentration against melatonin-induced pigment aggregation by 50% in Xenopus laevis dermal melanophore cell line
Assay data:5 Active, 32 Tested
Effective concentration required to produce 50% of the maximal pigment aggregation in Xenopus laevis dermal melanophore cell line
Assay data:36 Active, 4 Activity ≤ 1 nM, 29 Activity ≤ 1 µM, 37 Tested
Concentration producing half maximal aggregation of pigment granules in the centre of the melanophore isolated from the neural crest of Xenopus laevis embryos was determined
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µM
Agonistic activity was determined in a pigment aggregation model using cultured melanophores isolated from the neural crest of Xenopus laevis embryos
Assay data:3 Active, 2 Activity ≤ 1 µM, 4 Tested
Loss of righting reflex (LORR) in tadpoles was determined for anesthetic activity
Assay data:3 Active, 1 Activity ≤ 1 µM, 26 Tested
Loss of righting reflex (LORR) in Xenopus laevis tadpoles was determined for anesthetic activity
Assay data:1 Active, 1 Tested
Agonist activity at bfSPR to produce increase in intracellular [Ca2+]
Assay data:4 Active, 2 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
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