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CDK1/Cyclin B1 ADP-Glo Kinase Assay from US Patent US20240034731: "AZA-QUINAZOLINE COMPOUNDS AND METHODS OF USE"
Assay data:75 Active, 1 Activity ≤ 1 nM, 52 Activity ≤ 1 µM, 99 Tested
SummaryRelated BioAssays by Target
Inhibition of CDK1/cyclin B (unknown origin) at 10 uM by biochemical hotspot kinase assay
Assay data:1 Tested
Inhibition of C-terminal His6 tagged human full length CDK1/N-terminal GST-tagged human full length Cyclin B expressed in baculovirus infected Sf21 cells using 5-FAM-QSPKKG-CONH2 as substrate at 10 uM incubated for 60 mins in presence of ATP relative to control
Inhibition of C-terminal His6 tagged human full length CDK1/N-terminal GST-tagged human full length Cyclin B expressed in baculovirus infected Sf21 cells using 5-FAM-QSPKKG-CONH2 as substrate incubated for 60 mins in presence of ATP
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of CDK1/Cyclin B (unknown origin) in presence of ATP by scintillation counter analysis
Inhibition of CDK1/Cyclin B (unknown origin) at 1 uM incubated for 30 to 60 mins presence of dithiothreitol by Cheng-Prusoff equation analysis relative to control
Assay data:11 Tested
Inhibition of CDK1/Cyclin B (unknown origin) assessed as inhibition constant incubated for 30 to 60 mins presence of dithiothreitol by Cheng-Prusoff equation analysis
Assay data:10 Active, 10 Activity ≤ 1 µM, 10 Tested
Inhibition of CDK1/Cyclin B (unknown origin) assessed as inhibition constant
Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested
Inhibition of cdk1/Cyclin B (unknown origin)
Inhibition of CDK1/Cyclin B (unknown origin) in presence of gamma32P-ATP by scintillation counter analysis
Assay data:20 Active, 12 Activity ≤ 1 µM, 22 Tested
Inhibition of CDK1/cyclin B1 (unknown origin)
Inhibition of CDK1/cyclin B1 (unknown origin) assessed as substrate phosphorylation using ULight MBP peptide as substrate in presence of ATP incubated for 1 hr by FRET based LANCE Ultra KinaSelect screen assay
Assay data:1 Active, 1 Tested
Inhibition of CDK1/Cyclin B (unknown origin)
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Inhibition of human CDK1/Cyclin B in presence of gamma32P-ATP by scintillation counter analysis
CDK1/CyclinB1 Enzyme Reaction System from US Patent US20230303564: "PYRIMIDINE RING COMPOUND"
Assay data:5 Active, 5 Activity ≤ 1 µM, 5 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
No assay from US Patent US11759530: "TKI permeability enhancers"
Assay data:9 Active, 9 Activity ≤ 1 µM, 11 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibition of CDK1/cyclin B1 (unknown origin) preincubated for 10 mins followed by ATP and substrate addition and measured after 60 mins by HTRF analysis
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of recombinant CDK1/CycB1 (unknown origin) using CTD as substrate incubated for 60 mins by Beckman scintillation counter analysis
Protein Serine/Threonine Kinase, cdk1/Cyclin B Eurofins-Panlabs enzyme assay
Inhibition of CDK1/cyclinB (unknown origin) at 1 uM
SummaryPubMed CitationRelated BioAssays by Target
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