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Primary Screen for Target Class Profiling of Small Molecule Inhibitors of Methyltransferases
Assay data:968 Active, 24930 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Confirmatory Screen for Target Class Profiling of Small Molecule Inhibitors of Methyltransferases
Assay data:902 Active, 1111 Tested
Evaluation of Kd Values from US Patent US20240059728: "NOVEL GALACTOSIDE INHIBITOR OF GALECTINS"
Assay data:6 Active, 3 Activity ≤ 1 nM, 6 Activity ≤ 1 µM, 6 Tested
SummaryRelated BioAssays by Target
Cereblon Binding Assay from US Patent US20240059711: "Cereblon Ligands and Uses Thereof"
Assay data:15 Active, 10 Activity ≤ 1 µM, 15 Tested
Cereblon Binding Assay from US Patent US20240059704: "Cereblon Ligands and Uses Thereof"
Assay data:5 Active, 2 Activity ≤ 1 µM, 5 Tested
In Vitro Assay: IC50 Measurements for Binding to CRBN/DDB1 from US Patent US20240059704: "Cereblon Ligands and Uses Thereof"
Assay data:4 Active, 1 Activity ≤ 1 µM, 4 Tested
Coupled Nucleotide Exchange Assay from US Patent US20240059703: "HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE"
Assay data:506 Active, 473 Activity ≤ 1 µM, 513 Tested
DGAT2 Enzymatic Activity Assay from US Patent US20240059700: "NOVEL DIACYLGLYCERIDE O-ACYLTRANSFERASE 2 INHIBITORS"
Assay data:99 Active, 2 Activity ≤ 1 nM, 92 Activity ≤ 1 µM, 103 Tested
TBD from US Patent US20240059694: "COMPOUND CONTAINING 1,3-BENZODIOXOL STRUCTURE AND PREPARATION METHOD AND USE THEREOF"
Assay data:28 Active, 30 Activity ≤ 1 µM, 30 Tested
Assay data:30 Active, 30 Activity ≤ 1 µM, 30 Tested
Determination of Related Protease Inhibition from US Patent US20240059691: "ENZYME INHIBITORS"
Assay data:279 Active, 16 Activity ≤ 1 nM, 253 Activity ≤ 1 µM, 299 Tested
Determination of FXIIa Inhibition from US Patent US20240059691: "ENZYME INHIBITORS"
Assay data:275 Active, 166 Activity ≤ 1 µM, 340 Tested
THR/RXR Heterodimer Assay for Thyroid Hormone Receptor Agonist Screening from US Patent US20240059682: "THYROID HORMONE RECEPTOR BETA AGONIST COMPOUNDS"
Assay data:26 Active, 25 Activity ≤ 1 µM, 26 Tested
Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) Assay for Thyroid Hormone Receptor Agonist Screening from US Patent US20240059682: "THYROID HORMONE RECEPTOR BETA AGONIST COMPOUNDS"
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
THR Reporter Gene Method from US Patent US20240059676: "THYROID HORMONE RECEPTOR b SELECTIVE AGONIST COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF"
Assay data:32 Active, 21 Activity ≤ 1 µM, 38 Tested
Biochemical QPCT and QPCTL Activity Assay from US Patent US20240059675: "PIPERIDINYLPYRIDINYLCARBONITRILE DERIVATIVES AS INHIBITORS OF GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE AND GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE LIKE PROTEIN"
Assay data:36 Active, 8 Activity ≤ 1 nM, 36 Activity ≤ 1 µM, 36 Tested
In Vitro Kinase Binding Assay from US Patent US20240058459: "DENDRIMER COMPOSITIONS AND METHODS FOR DRUG DELIVERY TO THE EYE"
Assay data:3 Active, 2 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested
In Vitro JAK Kinase Assay from US Patent US20240058343: "TREATMENT OF URTICARIA USING JAK INHIBITORS"
Assay data:26 Active, 26 Activity ≤ 1 µM, 26 Tested
Potentiator Assay from US Patent US20240058315: "Pyridine and Pyrazine derivative for the Treatment of CF, COPD, and Bronchiectasis"
Assay data:13 Active, 13 Activity ≤ 1 µM, 13 Tested
Measurement of Inhibitory Activity on AT1 Receptor (AT1R)/AT2 Receptor (AT2R) from US Patent US11905274: "Receptor inhibitors, pharmaceutical compositions comprising the same and use thereof"
Assay data:72 Active, 71 Activity ≤ 1 µM, 72 Tested
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