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    Or2h1 olfactory receptor family 2 subfamily H member 1 [ Mus musculus (house mouse) ]

    Gene ID: 258470, updated on 8-Feb-2024

    Summary

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    Official Symbol
    Or2h1provided by MGI
    Official Full Name
    olfactory receptor family 2 subfamily H member 1provided by MGI
    Primary source
    MGI:MGI:2177474
    See related
    Ensembl:ENSMUSG00000095377 AllianceGenome:MGI:2177474
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Olfr91; MOR256-20; bM573K1.3
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Or2h1 in Genome Data Viewer
    Location:
    17 B1; 17 19.16 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (37403022..37443877, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (37092845..37132991, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene gamma-aminobutyric acid type B receptor subunit 1 Neighboring gene STARR-seq mESC enhancer starr_42506 Neighboring gene predicted gene, 41579 Neighboring gene olfactory receptor family 2 subfamily H member 2 Neighboring gene olfactory receptor family 2 subfamily H member 2C Neighboring gene UPF0368 protein Cxorf26 homolog Neighboring gene STARR-seq mESC enhancer starr_42507 Neighboring gene olfactory receptor family 2 subfamily H member 1B Neighboring gene von Hippel-Lindau tumor suppressor-like, pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Co-duplication of olfactory receptor and MHC class I genes in the mouse major histocompatibility complex. Amadou C, et al. Hum Mol Genet, 2003 Nov 15. PMID 14506126
    2. Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Lewandowski JP, et al. Dev Biol, 2015 Oct 1. PMID 26238476, Free PMC Article
    3. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
    4. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
    5. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    involved_in detection of chemical stimulus involved in sensory perception of smell IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within sensory perception of smell ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    olfactory receptor 91
    Names
    G-protein coupled receptor
    GA_x6K02T2PSCP-1533927-1532989
    bM573K1.3 (novel 7 transmembrane receptor (rhodopsin family) (olfactory receptor LIKE) protein)
    olfactory receptor MOR256-20

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_182714.2 → NP_874373.2  olfactory receptor 91

      See identical proteins and their annotated locations for NP_874373.2

      Status: VALIDATED

      Source sequence(s)
      BC119413
      Consensus CDS
      CCDS50107.1
      UniProtKB/TrEMBL
      Q2VPE0, Q78NX2, Q7TRL3
      Related
      ENSMUSP00000129446.2, ENSMUST00000087144.5
      Conserved Domains (1) summary
      cd15947
      Location:23 → 292
      7tmA_OR2B-like; olfactory receptor subfamily 2B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      37403022..37443877 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017317477.3 → XP_017172966.1  olfactory receptor 91 isoform X1

      UniProtKB/TrEMBL
      Q2VPE0, Q78NX2, Q7TRL3
      Related
      ENSMUSP00000150298.2, ENSMUST00000217372.2
      Conserved Domains (1) summary
      cd15947
      Location:23 → 292
      7tmA_OR2B-like; olfactory receptor subfamily 2B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
    Nucleotide Protein Strain
    Heading Accession and Version

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