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    Lman1l lectin, mannose-binding 1 like [ Mus musculus (house mouse) ]

    Gene ID: 235416, updated on 30-Apr-2024

    Summary

    Official Symbol
    Lman1lprovided by MGI
    Official Full Name
    lectin, mannose-binding 1 likeprovided by MGI
    Primary source
    MGI:MGI:2667537
    See related
    Ensembl:ENSMUSG00000056271 AllianceGenome:MGI:2667537
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    slamp
    Summary
    Predicted to enable mannose binding activity. Predicted to be involved in Golgi organization; endoplasmic reticulum organization; and endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in several cellular components, including COPII-coated ER to Golgi transport vesicle; Golgi membrane; and endoplasmic reticulum-Golgi intermediate compartment. Is expressed in metanephros and submandibular gland. Orthologous to human LMAN1L (lectin, mannose binding 1 like). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    NEW
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    Genomic context

    See Lman1l in Genome Data Viewer
    Location:
    9 B; 9 31.13 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (57514080..57528057, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (57607033..57620774, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene unc-51-like kinase 3 Neighboring gene complexin 3 Neighboring gene predicted gene, 32392 Neighboring gene c-src tyrosine kinase Neighboring gene STARR-positive B cell enhancer ABC_E9763 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:57498764-57498965 Neighboring gene cytochrome P450, family 1, subfamily a, polypeptide 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC28923

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables mannose binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in COPII-coated ER to Golgi transport vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein ERGIC-53-like
    Names
    ERGIC53-like protein
    LMAN1-like protein
    sublingual acinar membrane protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199222.3NP_954692.2  protein ERGIC-53-like precursor

      See identical proteins and their annotated locations for NP_954692.2

      Status: VALIDATED

      Source sequence(s)
      AB211986, AC122528, BY708954
      Consensus CDS
      CCDS52810.1
      UniProtKB/Swiss-Prot
      Q4H2F4, Q8VCD3
      Related
      ENSMUSP00000091352.5, ENSMUST00000093832.11
      Conserved Domains (1) summary
      cd06902
      Location:32255
      lectin_ERGIC-53_ERGL; ERGIC-53 and ERGL type 1 transmembrane proteins, N-terminal lectin domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      57514080..57528057 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036154901.1XP_036010794.1  protein ERGIC-53-like isoform X1