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ERDL6 Major facilitator superfamily protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 843859, updated on 7-Sep-2023

Summary

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Gene symbol
ERDL6
Gene description
Major facilitator superfamily protein
Primary source
Araport:AT1G75220
Locus tag
AT1G75220
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AtERDL6; ERD6-like 6; F22H5.6; F22H5_6
Summary
Encodes a vacuolar glucose exporter that is induced in response to factors that activate vacuolar glucose pools like darkness, heat stress and wounding and repressed during conditions that trigger glucose accumulation in the vacuole like cold stress and external sugar supply.
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Genomic context

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Location:
chromosome: 1
Exon count:
17
Sequence:
Chromosome: 1; NC_003070.9 (28229026..28233134, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene flavodoxin family protein / radical SAM domain-containing protein Neighboring gene HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase Neighboring gene DNA glycosylase superfamily protein Neighboring gene homeobox protein 33

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A novel Arabidopsis vacuolar glucose exporter is involved in cellular sugar homeostasis and affects the composition of seed storage compounds. Poschet G, et al. Plant Physiol, 2011 Dec. PMID 21984725, Free PMC Article
  2. A proteomics dissection of Arabidopsis thaliana vacuoles isolated from cell culture. Jaquinod M, et al. Mol Cell Proteomics, 2007 Mar. PMID 17151019, Free PMC Article
  3. Isolation and proteomic characterization of the Arabidopsis Golgi defines functional and novel components involved in plant cell wall biosynthesis. Parsons HT, et al. Plant Physiol, 2012 May. PMID 22430844, Free PMC Article
  4. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
  5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_106178.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables carbohydrate transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables sugar transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within glucose homeostasis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within positive regulation of seed germination IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus HDA PubMed 
located_in mitochondrion HDA PubMed 
located_in plant-type vacuole HDA PubMed 
located_in plant-type vacuole membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Major facilitator superfamily protein
NP_177658.1
  • Major facilitator superfamily protein; FUNCTIONS IN: carbohydrate transmembrane transporter activity, sugar:hydrogen symporter activity; INVOLVED IN: transport, transmembrane transport; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Sugar transporter, conserved site (InterPro:IPR005829), Major facilitator superfamily (InterPro:IPR020846), General substrate transporter (InterPro:IPR005828), Sugar/inositol transporter (InterPro:IPR003663), Major facilitator superfamily, general substrate transporter (InterPro:IPR016196); BEST Arabidopsis thaliana protein match is: Major facilitator superfamily protein (TAIR:AT1G19450.1); Has 32350 Blast hits to 31611 proteins in 2276 species: Archae - 620; Bacteria - 16081; Metazoa - 5271; Fungi - 6395; Plants - 2558; Viruses - 2; Other Eukaryotes - 1423 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    28229026..28233134 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_106178.4 → NP_177658.1  Major facilitator superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_177658.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9FRL3
    UniProtKB/TrEMBL
    A0A178WMP1, A0A5S9WUJ5, A0A654EP60
    Conserved Domains (1) summary
    cd17358
    Location:49 → 481
    MFS_GLUT6_8_Class3_like; Glucose transporter (GLUT) types 6 and 8, Class 3 GLUTs, and similar transporters of the Major Facilitator Superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9FRL3.1

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