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E12A11 PEBP (phosphatidylethanolamine-binding protein) family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 838390, updated on 15-Oct-2023

Summary

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Gene symbol
E12A11
Gene description
PEBP (phosphatidylethanolamine-binding protein) family protein
Primary source
Araport:AT1G18100
Locus tag
AT1G18100
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
MFT; MOTHER OF FT AND TFL1; T10F20.11
Summary
Encodes a member of the FT and TFL1 family of phosphatidylethanolamine-binding proteins. It is expressed in seeds and up-regulated in response to ABA. Loss of function mutants show decreased rate of germination in the presence of ABA. ABA dependent regulation is mediated by both ABI3 and ABI5. ABI5 promotes MFT expression, primarily in the radicle-hypocotyl transition zone and ABI3 suppresses it in the seed.
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Genomic context

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Location:
chromosome: 1
Exon count:
4
Sequence:
Chromosome: 1; NC_003070.9 (6227217..6230194, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene 5'-3' exonuclease family protein Neighboring gene ncRNA Neighboring gene miscRNA Neighboring gene Class II aaRS and biotin synthetases superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. MOTHER OF FT AND TFL1 regulates seed germination and fertility relevant to the brassinosteroid signaling pathway. Xi W, et al. Plant Signal Behav, 2010 Oct. PMID 20935478, Free PMC Article
  2. MOTHER OF FT AND TFL1 regulates seed germination through a negative feedback loop modulating ABA signaling in Arabidopsis. Xi W, et al. Plant Cell, 2010 Jun. PMID 20551347, Free PMC Article
  3. Temperature, light and nitrate sensing coordinate Arabidopsis seed dormancy cycling, resulting in winter and summer annual phenotypes. Footitt S, et al. Plant J, 2013 Jun. PMID 23590427, Free PMC Article
  4. A laboratory simulation of Arabidopsis seed dormancy cycling provides new insight into its regulation by clock genes and the dormancy-related genes DOG1, MFT, CIPK23 and PHYA. Footitt S, et al. Plant Cell Environ, 2017 Aug. PMID 28240777, Free PMC Article
  5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. using mutants in known dormancy-related genes [DELAY OF GERMINATION 1 (DOG1), MOTHER OF FLOWERING TIME (MFT), CBL-INTERACTING PROTEIN KINASE 23 (CIPK23) and PHYTOCHROME A (PHYA)] components of the circadian clock are shown to be involved in coordination of the annual seed dormancy cycle.
    Title: A laboratory simulation of Arabidopsis seed dormancy cycling provides new insight into its regulation by clock genes and the dormancy-related genes DOG1, MFT, CIPK23 and PHYA.
  2. Unlike DOG1, expression of MOTHER of FLOWERING TIME (MFT) has an opposite thermal response in seeds of the two ecotypes, and may therefore have a role in their different dormancy cycling phenotypes.
    Title: Temperature, light and nitrate sensing coordinate Arabidopsis seed dormancy cycling, resulting in winter and summer annual phenotypes.
  3. MFT function is also relevant to the brassinosteroids signaling pathway.
    Title: MOTHER OF FT AND TFL1 regulates seed germination and fertility relevant to the brassinosteroid signaling pathway.
  4. During seed germination, MFT promotes embryo growth by constituting a negative feedback loop in the ABA signaling pathway.
    Title: MOTHER OF FT AND TFL1 regulates seed germination through a negative feedback loop modulating ABA signaling in Arabidopsis.
Submit: New GeneRIF Correction

General gene information

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Homology

NM_101672.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within positive regulation of seed germination IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to abscisic acid IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
PEBP (phosphatidylethanolamine-binding protein) family protein
NP_173250.1
  • E12A11; CONTAINS InterPro DOMAIN/s: Phosphatidylethanolamine-binding, conserved site (InterPro:IPR001858), Phosphatidylethanolamine-binding protein PEBP (InterPro:IPR008914); BEST Arabidopsis thaliana protein match is: PEBP (phosphatidylethanolamine-binding protein) family protein (TAIR:AT5G03840.1); Has 2417 Blast hits to 2417 proteins in 371 species: Archae - 0; Bacteria - 118; Metazoa - 639; Fungi - 192; Plants - 1429; Viruses - 3; Other Eukaryotes - 36 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    6227217..6230194 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_101672.4 → NP_173250.1  PEBP (phosphatidylethanolamine-binding protein) family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_173250.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9XFK7
    UniProtKB/TrEMBL
    A0A178W7F0, A0A5S9V079
    Conserved Domains (1) summary
    cl00227
    Location:6 → 173
    PEBP; PhosphatidylEthanolamine-Binding Protein (PEBP) domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9XFK7.1

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