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Rpp25 ribonuclease P and MRP subunit p25 [ Rattus norvegicus (Norway rat) ]

Gene ID: 315705, updated on 5-Mar-2024

Summary

Official Symbol
Rpp25provided by RGD
Official Full Name
ribonuclease P and MRP subunit p25provided by RGD
Primary source
RGD:1305290
See related
Ensembl:ENSRNOG00000018812 AllianceGenome:RGD:1305290
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable ribonuclease P RNA binding activity. Predicted to contribute to ribonuclease P activity. Predicted to be involved in tRNA 5'-leader removal. Predicted to be located in centriolar satellite and nucleoplasm. Predicted to be part of multimeric ribonuclease P complex and ribonuclease MRP complex. Orthologous to human RPP25 (ribonuclease P and MRP subunit p25). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See Rpp25 in Genome Data Viewer
Location:
8q24
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (66803262..66804642)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (57907352..57908732)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (62283336..62284716)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene phosphopantothenoylcysteine decarboxylase Neighboring gene secretory carrier membrane protein 5 Neighboring gene uncharacterized LOC134480187 Neighboring gene small nucleolar RNA, H/ACA box 3C

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ribonuclease P RNA binding ISO
Inferred from Sequence Orthology
more info
 
enables ribonuclease P RNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 
contributes_to ribonuclease P activity ISO
Inferred from Sequence Orthology
more info
 
contributes_to ribonuclease P activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in tRNA 5'-leader removal IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in tRNA 5'-leader removal ISO
Inferred from Sequence Orthology
more info
 
involved_in tRNA 5'-leader removal ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in centriolar satellite IEA
Inferred from Electronic Annotation
more info
 
located_in centriolar satellite ISO
Inferred from Sequence Orthology
more info
 
part_of multimeric ribonuclease P complex ISO
Inferred from Sequence Orthology
more info
 
part_of multimeric ribonuclease P complex ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
part_of ribonuclease MRP complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of ribonuclease MRP complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
ribonuclease P protein subunit p25
Names
RNase P protein subunit p25
ribonuclease P 25 subunit
ribonuclease P/MRP 25 subunit
NP_001012124.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012124.1NP_001012124.1  ribonuclease P protein subunit p25

    See identical proteins and their annotated locations for NP_001012124.1

    Status: PROVISIONAL

    Source sequence(s)
    BC087592
    UniProtKB/Swiss-Prot
    Q5PPN2
    UniProtKB/TrEMBL
    A6J4V4
    Related
    ENSRNOP00000025408.2, ENSRNOT00000025410.4
    Conserved Domains (1) summary
    pfam01918
    Location:37101
    Alba; Alba

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    66803262..66804642
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)