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Gatd3a glutamine amidotransferase like class 1 domain containing 3A [ Mus musculus (house mouse) ]

Gene ID: 28295, updated on 5-Mar-2024

Summary

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Official Symbol
Gatd3aprovided by MGI
Official Full Name
glutamine amidotransferase like class 1 domain containing 3Aprovided by MGI
Primary source
MGI:MGI:1351861
See related
Ensembl:ENSMUSG00000053329 AllianceGenome:MGI:1351861
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ES1; Gatd3; C21orf33; D10Jhu81e
Summary
Located in mitochondrion. Is expressed in several structures, including genitourinary system; gut; nervous system; sensory organ; and thymus. Orthologous to human GATD3 (glutamine amidotransferase class 1 domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 190.1), heart adult (RPKM 107.5) and 27 other tissues See more
Orthologs
human all
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Genomic context

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See Gatd3a in Genome Data Viewer
Location:
10 C1; 10 39.72 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (77997900..78005589, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (78162066..78169755, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 51775 Neighboring gene icos ligand Neighboring gene STARR-positive B cell enhancer ABC_E5152 Neighboring gene STARR-positive B cell enhancer ABC_E6876 Neighboring gene STARR-positive B cell enhancer ABC_E2328 Neighboring gene predicted gene, 47922 Neighboring gene STARR-positive B cell enhancer ABC_E6877 Neighboring gene STARR-seq mESC enhancer starr_27217 Neighboring gene PWP2 periodic tryptophan protein homolog (yeast) Neighboring gene trafficking protein particle complex 10

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Nedd1 expression as a marker of dynamic centrosomal localization during mouse embryonic development. Manning JA, et al. Histochem Cell Biol, 2008 Jun. PMID 18239929
  2. Bardet-Biedl Syndrome proteins regulate cilia disassembly during tissue maturation. Patnaik SR, et al. Cell Mol Life Sci, 2019 Feb. PMID 30446775, Free PMC Article
  3. Perfect conserved linkage across the entire mouse chromosome 10 region homologous to human chromosome 21. Wiltshire T, et al. Genome Res, 1999 Dec. PMID 10613844, Free PMC Article
  4. Characterization of the Cardiac Overexpression of HSPB2 Reveals Mitochondrial and Myogenic Roles Supported by a Cardiac HspB2 Interactome. Grose JH, et al. PLoS One, 2015. PMID 26465331, Free PMC Article
  5. A gene expression map of human chromosome 21 orthologues in the mouse. Gitton Y, et al. Nature, 2002 Dec 5. PMID 12466855

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
glutamine amidotransferase-like class 1 domain-containing protein 3, mitochondrial
Names
ES1 protein homolog, mitochondrial
glutamine amidotransferase-like class 1 domain-containing protein 3A, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001364646.1 → NP_001351575.1  glutamine amidotransferase-like class 1 domain-containing protein 3, mitochondrial isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AC164573
    UniProtKB/TrEMBL
    A0A1W2P7B6
    Related
    ENSMUSP00000151605.2, ENSMUST00000219120.2
    Conserved Domains (1) summary
    cl00020
    Location:43 → 233
    GAT_1; Type 1 glutamine amidotransferase (GATase1)-like domain

  2. NM_138601.3 → NP_613067.1  glutamine amidotransferase-like class 1 domain-containing protein 3, mitochondrial isoform 1 precursor

    See identical proteins and their annotated locations for NP_613067.1

    Status: VALIDATED

    Source sequence(s)
    AI852165, AK003866
    Consensus CDS
    CCDS35957.1
    UniProtKB/Swiss-Prot
    Q9D172
    Related
    ENSMUSP00000001242.8, ENSMUST00000001242.9
    Conserved Domains (1) summary
    cd03133
    Location:43 → 264
    GATase1_ES1; Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    77997900..78005589 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D172.1 GenPept UniProtKB/Swiss-Prot:Q9D172

Gene LinkOut

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