Hba-a2 hemoglobin alpha, adult chain 2 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Hba-a2provided by MGI
Official Full Name: hemoglobin alpha, adult chain 2provided by MGI
Primary source: MGI:MGI:96016
See related: Ensembl:ENSMUSG00000069917 AllianceGenome:MGI:96016
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary: Acts upstream of or within erythrocyte development; in utero embryonic development; and response to bacterium. Is expressed in visceral pericardium and yolk sac. [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in spleen adult (RPKM 52386.2), heart adult (RPKM 17186.2) and 4 other tissues See more
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 11 A4; 11 18.87 cM

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	11	NC_000077.7 (32246492..32247310)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	11	NC_000077.6 (32296492..32297310)

Chromosome 11 - NC_000077.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)
Radiation induced (1) 1 citation

General gene information

Go to the top of the page Help

Markers

Hba-a1 (e-PCR), detects polymorphism
- UniSTS:470555

Hba-a1 (e-PCR), detects polymorphism
- UniSTS:525964

Hba-a1 (e-PCR), detects polymorphism
- UniSTS:516521

Hba-a1 (e-PCR), detects polymorphism
- UniSTS:143317

Hba-a1 (e-PCR), detects polymorphism
- UniSTS:143318

UniSTS:465391 (e-PCR)
- UniSTS:465391

Hba-a1 (e-PCR), detects polymorphism
- UniSTS:465391

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables G protein-coupled receptor binding	ISO Inferred from Sequence Orthology more info
contributes_to haptoglobin binding	ISO Inferred from Sequence Orthology more info
contributes_to peroxidase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within erythrocyte development	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within in utero embryonic development	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within response to bacterium	IEP Inferred from Expression Pattern more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular space	ISO Inferred from Sequence Orthology more info
part_of haptoglobin-hemoglobin complex	ISO Inferred from Sequence Orthology more info
part_of hemoglobin complex	ISO Inferred from Sequence Orthology more info

General protein information

Go to the top of the page Help

Preferred Names: hemoglobin alpha, adult chain 2

Names: alpha 2 globin

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.