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Links from GEO DataSets

Items: 8

1.

Association of Molecular Subtypes with Pathologic Response, PFS and OS in a Phase II Study of Coexpression Extrapolation (COXEN) with Neoadjuvant Chemotherapy (NAC) for Localized, Muscle-Invasive Bladder Cancer (SWOG S1314; NCT02177695)

(Submitter supplied) Investigation of RNA-based molecular subtypes as additional predictive biomarkers for neoadjuvant chemotherapy response, progression-free survival and survival in patients treated in S1314.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
189 Samples
Download data: CEL
Series
Accession:
GSE244266
ID:
200244266

PubMed Similar studies Analyze with GEO2R

2.

Cell-free DNA methylation as a predictive biomarker of response to neoadjuvant chemotherapy for patients with muscle invasive bladder cancer in SWOG S1314

(Submitter supplied) cfDNA methylation analysis to predict cisplatin treatment response in bladder cancer
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
Platform:
GPL21145
137 Samples
Download data: IDAT, TXT
Series
Accession:
GSE193208
ID:
200193208

PubMed Similar studies

3.

Impact of molecular subtypes in muscle-invasive bladder cancer on predicting response and survival outcome to neoadjuvant chemotherapy: results from a multi-institutional validation study

(Submitter supplied) Four different molecular classifications of muscle-invasive bladder cancer (MIBC) based on gene expression have been proposed. With the ultimate goal of utilizing these molecular subtypes for personalized treatment, we investigated their significance in the context of neoadjuvant cisplatin-based chemotherapy (NAC).
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL22995
305 Samples
Download data: CEL
Series
Accession:
GSE87304
ID:
200087304

PubMed Similar studies Analyze with GEO2R

4.

MVAC treated tumors

(Submitter supplied) validation of the survival outcomes from MVAC-Avastin treated tumors
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL14951
49 Samples
Download data: TXT
Series
Accession:
GSE70691
ID:
200070691

PubMed Full text in PMC Similar studies Analyze with GEO2R

5.

a phase 2 trial of DDMVAC and bevacizumab in urothelial cancer

(Submitter supplied) A prognostic gene expression signature in chemotherapy-naïve bladder cancer is predictive of clinical outcomes from neoadjuvant chemotherapy
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL14951
61 Samples
Download data: TXT
Series
Accession:
GSE69795
ID:
200069795

PubMed Full text in PMC Similar studies Analyze with GEO2R

6.

Differential neoadjuvant chemotherapy response in urothelial carcinoma molecular subtypes

(Submitter supplied) For patients with muscle-invasive bladder cancer, there are no biomarkers in clinical use that can identify patients that are sensitive or resistant to neoadjuvant chemotherapy. This study investigates how molecular subtypes impact pathological response and survival in 149 patients receiving preoperative cis-platin based chemotherapy by tumor classification using transcriptomic profiling and a 13-marker immunostaining panel. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6244
149 Samples
Download data: CEL, TXT
Series
Accession:
GSE169455
ID:
200169455

PubMed Similar studies

7.

Divergent biological response to neoadjuvant chemotherapy in muscle-invasive bladder cancer

(Submitter supplied) Despite cisplatin-based neoadjuvant chemotherapy (NAC) 60% of patients with muscle-invasive bladder cancer still have residual invasive disease at radical cystectomy (RC). The NAC-induced biological alterations in these cisplatin-resistant tumors remain largely unstudied. We analyzed gene expression from 133 patients with residual invasive disease after cisplatin-based NAC. H&E and immunohistochemistry were used to confirm tissue sampling and gene expression analysis. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL22995
133 Samples
Download data: CEL
Series
Accession:
GSE124305
ID:
200124305

PubMed Similar studies Analyze with GEO2R

8.

Impact of Immune and Stromal Infiltration on Outcomes Following Bladder-Sparing Trimodality Therapy for Muscle-Invasive Bladder Cancer

(Submitter supplied) Background: Bladder-sparing trimodality therapy (TMT) is an alternative to radical cystectomy (RC) for muscle-invasive bladder cancer (MIBC), and biomarkers to inform therapy selection are needed. Objective: To evaluate immune and stromal signatures in MIBC treated with TMT.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL22995
136 Samples
Download data: CEL
Series
Accession:
GSE128701
ID:
200128701

PubMed Full text in PMC Similar studies Analyze with GEO2R

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