Similar studies for GEO DataSets (Select 200241659) - GEO DataSets

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Items: 2

Select item 2002416591.

Efficient genetic editing of human intestinal organoids using ribonucleoprotein-based CRISPR

(Submitter supplied) Organoids are currently one of the most widely used ex vivo models in epithelial biology. Combined with genetic editing strategies, organoids offer a promise of rapid and efficient investigation of gene function in many models of human disease. However, to date, the editing efficiency of organoids with the use of non-viral electroporation methods has been only up to 30%, with implications for the subsequent need for selection including turnaround time and exhaustion or adaptation of the organoid population. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24676
7 Samples

Download data: TSV

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Accession:: GSE241659

ID:: 200241659

PubMed Full text in PMC Similar studies

Select item 2000787292.

CRISPResso: sequencing analysis toolbox for CRISPR genome editing

(Submitter supplied) CRISPResso is a software pipeline for the analysis of targeted CRISPR-Cas9 deep sequencing data. This algorithm allows for the quantification of both non-homologous end joining (NHEJ) and homologous directed repair (HDR) occurrences (https://github.com/lucapinello/CRISPResso)