GEO DataSets

(Submitter supplied) The study critically evaluate the results of 16S targeted amplicon sequencing performed on the total DNA collected from healthy donors’ blood samples in the light of specific negative controls.

Organism:

Escherichia coli; Mus musculus; human blood metagenome

Type:

Other

Platforms:

GPL34159 GPL16085 GPL16417

15 Samples

Download data: FASTA, TSV, TXT

(Submitter supplied) The impact of the microbiome on HIV disease is widely acknowledged although the mechanisms downstream of fluctuations in microbial composition remain speculative. We detected rapid, dynamic changes in translocated microbial constituents during two years after cART initiation. An unbiased systems biology approach revealed two distinct pathways driven by changes in the abundance ratio of Serratia to other bacterial genera. more...

Organism:

Homo sapiens; human blood metagenome

Type:

Expression profiling by high throughput sequencing; Other

Platforms:

GPL30076 GPL20301

514 Samples

Download data: XLSX

(Submitter supplied) An increasing body of evidence suggests an important role of the human microbiome in health and disease. We propose a ‘lost and found’ pipeline, which examines high quality unmapped sequence reads for microbial taxonomic classification. Using this pipeline, we are able to detect bacterial and archaeal phyla in blood using RNA sequencing (RNA-Seq) data. Careful analyses, including the use of positive and negative control datasets, suggest that these detected phyla represent true microbial communities in whole blood and are not due to contaminants. more...

Organism:

human blood metagenome

Type:

Other

Platform:

GPL21801

192 Samples

Download data: FASTQ