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Items: 15

1.

Genes regulated in EML1 cells expressing the TEL-AML1 oncogene after 5 and 7 days of treatment with IL7 and FLT3 ligand.

(Submitter supplied) The t(12;21) translocation is the most common genetic rearrangement in childhood acute lymphoblastic leukemia (ALL) and gives rise to the TEL-AML1 fusion gene, which functions as a transcription factor. TEL-AML1 expression in EML1 cells results in an impairment of differentiation along the B-lymphoid lineage.
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS5661
Platform:
GPL11533
12 Samples
Download data: CEL
Series
Accession:
GSE64919
ID:
200064919

Analyze with GEO2R

2.
Full record GDS5661

Interleukin 7 and FLT-3 ligand effect on EML1 HSPC line expressing acute lymphoblastic leukemia TEL-AML1 fusion protein: time course

Analysis of TEL-AML1 oncogene-expressing hematopoietic stem/progenitor cell line EML1 treated with interleukin 7 (IL7) and FLT3 ligand (FLT3L) for up to 7 days. IL7 and FLT3L treatment induces B-cell differentiation. Results provide insight into the role of TEL-AML1 in early B-cell differentiation.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation, 2 protocol, 3 time sets
Platform:
GPL11533
Series:
GSE64919
12 Samples
Download data: CEL
DataSet
Accession:
GDS5661
ID:
5661

Analyze DataSet

3.

[MoGene-1_1-st] Affymetrix Mouse Gene 1.1 ST Array [transcript (gene) version]

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html MoGene-1_1-st-v1.na31.mm9.transcript.csv #%create_date=Fri Aug 27 17:50:02 2010 PDT #%chip_type=MoGene-1_1-st-v1 #%lib_set_name=MoGene-1_1-st #%lib_set_version=v1 #%genome-species=Mus musculus #%genome-version=mm9 #%genome-version-ucsc=mm9 #%genome-version-ncbi=37 #%genome-version-create_date=2007-07-00 #%genome-lifted-method=liftOver #%genome-lifted_from-species=Mus musculus #%genome-lifted_from-version-ucsc=mm8 #%genome-lifted_from-version-ncbi=36 #%netaffx-annotation-date=2010-07-15 #%netaffx-annotation-netaffx-build=31 Protocol: see manufacturer's web site
Organism:
Mus musculus
10 DataSets
173 Series
7 Related Platforms
4209 Samples
Download data
Platform
Accession:
GPL11533
ID:
100011533

4.

EML1 infected with the TEL-AML1 ccs cloned into thepWPI lentiviral vector treated with IL7 and FLT3L for 7 days- rep 2

Organism:
Mus musculus
Source name:
EML1 hematopoietic progenitor cell line
Platform:
GPL11533
Series:
GSE64919
Dataset:
GDS5661
Download data: CEL
Sample
Accession:
GSM1583310
ID:
301583310

5.

EML1 infected with the TEL-AML1 ccs cloned into thepWPI lentiviral vector treated with IL7 and FLT3L for 7 days- rep 1

Organism:
Mus musculus
Source name:
EML1 hematopoietic progenitor cell line
Platform:
GPL11533
Series:
GSE64919
Dataset:
GDS5661
Download data: CEL
Sample
Accession:
GSM1583309
ID:
301583309

6.

EML1 infected with the TEL-AML1 ccs cloned into thepWPI lentiviral vector treated with IL7 and FLT3L for 5 days- rep 2

Organism:
Mus musculus
Source name:
EML1 hematopoietic progenitor cell line
Platform:
GPL11533
Series:
GSE64919
Dataset:
GDS5661
Download data: CEL
Sample
Accession:
GSM1583308
ID:
301583308

7.

EML1 infected with the TEL-AML1 ccs cloned into thepWPI lentiviral vector treated with IL7 and FLT3L for 5 days- rep 1

Organism:
Mus musculus
Source name:
EML1 hematopoietic progenitor cell line
Platform:
GPL11533
Series:
GSE64919
Dataset:
GDS5661
Download data: CEL
Sample
Accession:
GSM1583307
ID:
301583307

8.

EML1 infected with the TEL-AML1 ccs cloned into thepWPI lentiviral vector - rep 2

Organism:
Mus musculus
Source name:
EML1 hematopoietic progenitor cell line
Platform:
GPL11533
Series:
GSE64919
Dataset:
GDS5661
Download data: CEL
Sample
Accession:
GSM1583306
ID:
301583306

9.

EML1 infected with the TEL-AML1 ccs cloned into thepWPI lentiviral vector - rep 1

Organism:
Mus musculus
Source name:
EML1 hematopoietic progenitor cell line
Platform:
GPL11533
Series:
GSE64919
Dataset:
GDS5661
Download data: CEL
Sample
Accession:
GSM1583305
ID:
301583305

10.

EML1 infected with the empty pWPI lentiviral vector treated with IL7 and FLT3L for 7 days- rep 2

Organism:
Mus musculus
Source name:
EML1 hematopoietic progenitor cell line
Platform:
GPL11533
Series:
GSE64919
Dataset:
GDS5661
Download data: CEL
Sample
Accession:
GSM1583304
ID:
301583304

11.

EML1 infected with the empty pWPI lentiviral vector treated with IL7 and FLT3L for 7 days- rep 1

Organism:
Mus musculus
Source name:
EML1 hematopoietic progenitor cell line
Platform:
GPL11533
Series:
GSE64919
Dataset:
GDS5661
Download data: CEL
Sample
Accession:
GSM1583303
ID:
301583303

12.

EML1 infected with the empty pWPI lentiviral vector treated with IL7 and FLT3L for 5 days- rep 2

Organism:
Mus musculus
Source name:
EML1 hematopoietic progenitor cell line
Platform:
GPL11533
Series:
GSE64919
Dataset:
GDS5661
Download data: CEL
Sample
Accession:
GSM1583302
ID:
301583302

13.

EML1 infected with the empty pWPI lentiviral vector treated with IL7 and FLT3L for 5 days- rep 1

Organism:
Mus musculus
Source name:
EML1 hematopoietic progenitor cell line
Platform:
GPL11533
Series:
GSE64919
Dataset:
GDS5661
Download data: CEL
Sample
Accession:
GSM1583301
ID:
301583301

14.

EML1 infected with the empty pWPI lentiviral vector - rep 2

Organism:
Mus musculus
Source name:
EML1 hematopoietic progenitor cell line
Platform:
GPL11533
Series:
GSE64919
Dataset:
GDS5661
Download data: CEL
Sample
Accession:
GSM1583300
ID:
301583300

15.

EML1 infected with the empty pWPI lentiviral vector - rep 1

Organism:
Mus musculus
Source name:
EML1 hematopoietic progenitor cell line
Platform:
GPL11533
Series:
GSE64919
Dataset:
GDS5661
Download data: CEL
Sample
Accession:
GSM1583299
ID:
301583299

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