GSE58120[Accession] - GEO DataSets - NCBI

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Items: 15

Select item 2000581201.

Dendritic cell-derived IL-2 promotes apoptosis of terminally mature cells via a novel autocrine signaling pathway

(Submitter supplied) Dendritic cells (DCs) are crucial for sensing pathogens and triggering immune response. GM-CSF myeloid dendritic cells (GM-DCs) secrete several cytokines including IL-2 upon activation by pathogen associated molecular pattern (PAMP) ligands. DC IL-2 has been shown to be important for innate and adaptive immune responses, however its importance in DC physiology has never been demonstrated. This is due to ambiguity in expression of the CD122 subunit of the IL-2 trimeric receptor complex crucial for signaling. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS5665
Platform:: GPL6246
12 Samples

Download data: CEL

Series

Accession:: GSE58120

ID:: 200058120

PubMed Similar studies Analyze with GEO2R

Select item 56652.

Full record GDS5665

Pathogen-associated molecular-pattern curdlan effect on interleukin-2 deficient GM-CSF myeloid dendritic cells

Analysis of GM-CSF myeloid dendritic cells (GM-DCs) isolated from interleukin-2 (IL-2) knockouts and activated with curdlan, a pathogen-associated molecular pattern (PAMP). GM-DCs secrete cytokines such as IL-2, upon PAMP activation. Results provide insight into role of IL-2 signaling in DCs.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 2 agent, 2 genotype/variation sets

Platform:: GPL6246
Series:: GSE58120
12 Samples

Download data: CEL

DataSet

Accession:: GDS5665

ID:: 5665

PubMed Similar studies GEO Profiles Analyze DataSet

Select item 1000062463.

[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version]

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: See manufacturer's web site

Organism:: Mus musculus

143 DataSets
2496 Series
28 Related Platforms
30138 Samples

Platform

Accession:: GPL6246

ID:: 100006246

Select item 3014013024.

IL2 knockout GM-DCs treated with curdlan for 6 hours, replicate 3

Organism:: Mus musculus

Source name:: GM-DC derived from bone marrow and selected using CD11c microbeads

Platform:: GPL6246
Series:: GSE58120
Dataset:: GDS5665

Download data: CEL

Sample

Accession:: GSM1401302

ID:: 301401302

Select item 3014013015.

IL2 knockout GM-DCs treated with curdlan for 6 hours, replicate 1

Organism:: Mus musculus

Source name:: GM-DC derived from bone marrow and selected using CD11c microbeads

Platform:: GPL6246
Series:: GSE58120
Dataset:: GDS5665

Download data: CEL

Sample

Accession:: GSM1401301

ID:: 301401301

Select item 3014013006.

Wild type GM-DCs, replicate 3

Organism:: Mus musculus

Source name:: GM-DC derived from bone marrow and selected using CD11c microbeads

Platform:: GPL6246
Series:: GSE58120
Dataset:: GDS5665

Download data: CEL

Sample

Accession:: GSM1401300

ID:: 301401300

Select item 3014012997.

Wild type GM-DCs treated with curdlan for 6 hours, replicate 1

Organism:: Mus musculus

Source name:: GM-DC derived from bone marrow and selected using CD11c microbeads

Platform:: GPL6246
Series:: GSE58120
Dataset:: GDS5665

Download data: CEL

Sample

Accession:: GSM1401299

ID:: 301401299

Select item 3014012988.

IL2 knockout GM-DCs, replicate 1

Organism:: Mus musculus

Source name:: GM-DC derived from bone marrow and selected using CD11c microbeads

Platform:: GPL6246
Series:: GSE58120
Dataset:: GDS5665

Download data: CEL

Sample

Accession:: GSM1401298

ID:: 301401298

Select item 3014012979.

IL2 knockout GM-DCs treated with curdlan for 6 hours, replicate 2

Organism:: Mus musculus

Source name:: GM-DC derived from bone marrow and selected using CD11c microbeads

Platform:: GPL6246
Series:: GSE58120
Dataset:: GDS5665

Download data: CEL

Sample

Accession:: GSM1401297

ID:: 301401297

Select item 30140129610.

Wild type GM-DCs treated with curdlan for 6 hours, replicate 3

Organism:: Mus musculus

Source name:: GM-DC derived from bone marrow and selected using CD11c microbeads

Platform:: GPL6246
Series:: GSE58120
Dataset:: GDS5665

Download data: CEL

Sample

Accession:: GSM1401296

ID:: 301401296

Select item 30140129511.

Wild type GM-DCs, replicate 2

Organism:: Mus musculus

Source name:: GM-DC derived from bone marrow and selected using CD11c microbeads

Platform:: GPL6246
Series:: GSE58120
Dataset:: GDS5665

Download data: CEL

Sample

Accession:: GSM1401295

ID:: 301401295

Select item 30140129412.

Wild type GM-DCs treated with curdlan for 6 hours, replicate 2

Organism:: Mus musculus

Source name:: GM-DC derived from bone marrow and selected using CD11c microbeads

Platform:: GPL6246
Series:: GSE58120
Dataset:: GDS5665

Download data: CEL

Sample

Accession:: GSM1401294

ID:: 301401294

Select item 30140129313.

IL2 knockout GM-DCs, replicate 3

Organism:: Mus musculus

Source name:: GM-DC derived from bone marrow and selected using CD11c microbeads

Platform:: GPL6246
Series:: GSE58120
Dataset:: GDS5665

Download data: CEL

Sample

Accession:: GSM1401293

ID:: 301401293

Select item 30140129214.

IL2 knockout GM-DCs, replicate 2

Organism:: Mus musculus

Source name:: GM-DC derived from bone marrow and selected using CD11c microbeads

Platform:: GPL6246
Series:: GSE58120
Dataset:: GDS5665

Download data: CEL

Sample

Accession:: GSM1401292

ID:: 301401292

Select item 30140129115.

Wild type GM-DCs, replicate 1

Organism:: Mus musculus

Source name:: GM-DC derived from bone marrow and selected using CD11c microbeads

Platform:: GPL6246
Series:: GSE58120
Dataset:: GDS5665

Download data: CEL

Sample

Accession:: GSM1401291

ID:: 301401291

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