GEO DataSets

(Submitter supplied) We have developed a whole organ mapping approach which combines microscopic assessment of the entire mucosal membrane of the organ affected by cancer with comprehensive genomic profiling. It was used to study the chronology of the molecular changes in the human bladder as they evolved from mucosal field effect through dysplasia and carcinoma in situ to multifocal carcinoma. The widespread methylation changes involving almost the entire mucosa were identified as a major mechanism driving the development of the initial field effect. more...

Organism:

Homo sapiens

Type:

SNP genotyping by SNP array; Genome variation profiling by SNP array; Methylation profiling by high throughput sequencing

Platforms:

GPL26040 GPL9886

61 Samples

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