"PreventionGenetics, part of Exact Sciences"[submitter] AND "WRAP53"[g - ClinVar

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Items: 22

	Variation	Gene (Protein Change)	Type (Consequence)	Condition	Classification, Review status
Select item 325650	NM_001143992.2(WRAP53):c.31C>T (p.Pro11Ser)	TP53, WRAP53 (P11S)	Single nucleotide variant (missense variant)	not specified +6 more	GBenign/Likely benign
Select item 261001	NM_001143992.2(WRAP53):c.202C>G (p.Arg68Gly)	TP53, WRAP53 (R68G)	Single nucleotide variant (missense variant)	not provided +4 more	GBenign
Select item 2883743	NM_001143992.2(WRAP53):c.297T>C (p.Ser99=)	WRAP53	Single nucleotide variant (synonymous variant)	not provided +1 more	GLikely benign
Select item 261002	NM_001143992.2(WRAP53):c.407C>G (p.Pro136Arg)	TP53, WRAP53 (P136R)	Single nucleotide variant (missense variant)	Dyskeratosis congenita, autosomal recessive 3 +4 more	GBenign/Likely benign
Select item 3046163	NM_001143992.2(WRAP53):c.411T>C (p.Ala137=)	WRAP53	Single nucleotide variant (synonymous variant)	WRAP53-related disorder	GLikely benign
Select item 261003	NM_001143992.2(WRAP53):c.450C>T (p.Phe150=)	TP53, WRAP53	Single nucleotide variant (synonymous variant)	Dyskeratosis congenita +4 more	GBenign/Likely benign
Select item 626052	NM_001143992.2(WRAP53):c.550A>C (p.Ile184Leu)	WRAP53 (I184L)	Single nucleotide variant (missense variant)	WRAP53-related disorder +1 more	GUncertain significance
Select item 1547741	NM_001143992.2(WRAP53):c.780C>T (p.Phe260=)	WRAP53	Single nucleotide variant (synonymous variant)	WRAP53-related disorder +1 more	GBenign/Likely benign
Select item 1460977	NM_001143992.2(WRAP53):c.792C>T (p.Leu264=)	WRAP53	Single nucleotide variant (synonymous variant)	not provided +1 more	GLikely benign
Select item 1163410	NM_001143992.2(WRAP53):c.919C>T (p.Arg307Trp)	WRAP53 (R307W)	Single nucleotide variant (missense variant)	not specified +2 more	GUncertain significance
Select item 761716	NM_001143992.2(WRAP53):c.956-8C>T	WRAP53	Single nucleotide variant (intron variant)	not provided +1 more	GLikely benign
Select item 392640	NM_001143992.2(WRAP53):c.1075C>T (p.Pro359Ser)	WRAP53 (P359S)	Single nucleotide variant (missense variant)	WRAP53-related disorder +3 more	GConflicting classifications of pathogenicity
Select item 1662004	NM_001143992.2(WRAP53):c.1131C>T (p.Pro377=)	WRAP53	Single nucleotide variant (synonymous variant)	not provided +1 more	GLikely benign
Select item 260995	NM_001143992.2(WRAP53):c.1223G>A (p.Gly408Asp)	WRAP53 (G408D)	Single nucleotide variant (missense variant)	not provided +1 more	GConflicting classifications of pathogenicity
Select item 2183457	NM_001143992.2(WRAP53):c.1257C>T (p.Phe419=)	WRAP53	Single nucleotide variant (synonymous variant)	not provided +1 more	GLikely benign
Select item 260996	NM_001143992.2(WRAP53):c.1308T>C (p.Ala436=)	WRAP53	Single nucleotide variant (synonymous variant)	Dyskeratosis congenita +3 more	GBenign
Select item 260997	NM_001143992.2(WRAP53):c.1359C>T (p.Pro453=)	WRAP53	Single nucleotide variant (synonymous variant)	not specified +2 more	GBenign/Likely benign
Select item 260998	NM_001143992.2(WRAP53):c.1482A>G (p.Glu494=)	WRAP53	Single nucleotide variant (synonymous variant)	Dyskeratosis congenita +2 more	GBenign/Likely benign
Select item 742999	NM_001143992.2(WRAP53):c.1521C>T (p.His507=)	WRAP53	Single nucleotide variant (synonymous variant)	Dyskeratosis congenita +3 more	GConflicting classifications of pathogenicity
Select item 2636148	NM_001143992.2(WRAP53):c.1565delinsGG (p.Ala522fs)	WRAP53 (A522fs)	Indel (frameshift variant)	WRAP53-related disorder	GUncertain significance
Select item 260999	NM_001143992.2(WRAP53):c.1565C>G (p.Ala522Gly)	WRAP53 (A522G)	Single nucleotide variant (missense variant)	not provided +3 more	GBenign
Select item 261000	NM_001143992.2(WRAP53):c.1641G>T (p.Leu547=)	WRAP53	Single nucleotide variant (synonymous variant)	Dyskeratosis congenita +2 more	GBenign/Likely benign

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Items: 22