Conserved Protein Domain Family
TRAP-gamma
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pfam07074: TRAP-gamma 
Translocon-associated protein, gamma subunit (TRAP-gamma)
This family consists of several eukaryotic translocon-associated protein, gamma subunit (TRAP-gamma) sequences. The translocation site (translocon), at which nascent polypeptides pass through the endoplasmic reticulum membrane, contains a component previously called 'signal sequence receptor' that is now renamed as 'translocon-associated protein' (TRAP). The TRAP complex is comprised of four membrane proteins alpha, beta, gamma and delta which are present in a stoichiometric relation, and are genuine neighbours in intact microsomes. The gamma subunit is predicted to span the membrane four times.
Links
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Statistics
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PSSM-Id: 399809
Aligned: 15 rows
Threshold Bit Score: 204.158
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q6DEU2        12 EEDLLLQDFSRNLSAKSSALFYGNAFIVSAIPIWLYWRIWHMDLVQSAVLYTVMTLVSTYLVAFAYKNVKFVLKHKVAQK 91  tropical clawed...
XP_001951873  14 EEEQLLSDFSRNVSTKSSALFYGSAFMVSALPIWLYWRIHMIEMLPALVWFILVTLGSTYLISFAYKNTKFILKHKIAIK 93 
EDO39583      10 EDELLLQNFSRSVSTKSSILFYANALIVSAIPLWLFWRIHQMDPYSSGILFAVMTLVSTWLVAFAYKNVKFQLKHKIAQR 89 
XP_002066423  17 EEELLLQDFSRNVSTKSSALFYGNAFIVSAVPIWLFWRIHNMDLWPSSILFVLVTAASTYLMATAYKNIKFQLKHKIASR 96 
EEC13285      91 EEELLLQDFSRNVSTKSSALFYGNAFIVSAIPIWLFWRIHQMDLYQSAIVFAVMTLLCTWLIAFAYKSVKFVLKHKVAPK 170
Q1HRN7        12 EEELLLQDFSRNVSTKSNALFYGNAFMISAVPIWLFWRVHQMELLPSLVFFAIVTGLCTYLMAMAYKNTKFTLKHKIANK 91  yellow fever mo...
OWR42219      12 EEELLLQDFSRNVSTKSSALFYGNAFIVSAIPIWLFWRVHALEVSSSLAWFAIVTVASTWLLALAYRNTKFQLKHRVAVR 91 
XP_002131637  11 EEELLLQDFGRDLSRKSSVIFYVHALFVSAIPLWLFNRIHQMEMLDNAILFVIGTIFSAYFVALAYKNNKFELKHKIAQK 90 
CAP34679       7 EEEMLLSSYSASSSTKGTLFFYVNALILSLAPLYLFYGVHQMEVADSLVVWTLSAAGTAYLLVMACKNQKKLLKHQIVMK 86 
EFO20117      12 EDELLLKDFSAAVSTKGSALFYGNSTVIAIAPLYLFHGIHQMEVADSWIIWLISSLTASYLISFAYKNIKHILKHKIVVK 91 

Q6DEU2        92 REDAVSREVTRKLseADNRKMSRKEKDERILWKKNEVADYEATTFSIFYNNTLFLVLVIVASFFLLKNFNPTVNYILSIS 171 tropical clawed...
XP_001951873  94 REEAVTREITRKY--ADDKKISKKEKDEKALFQKNDVADYEATAFSIFYNNALFLVIVVLLSFYLLKGFSTTANYIFSVG 171
EDO39583      90 RDAAITKEVNQEL--DPNKKLTRQEKDERILWKKNKVADMEAMTFSIFYNNALYLFLVLFASFYALRSLHPSANYLLSTS 167
XP_002066423  97 REEAVTREVNRQL--GDDKKVTRKEKDERILWKKNEVADYEATTYSIFYNNALFLAIIIFISFFLLKNISPFVNYIFSIG 174
EEC13285     171 REDAVSREIMKKL--SDDKKMSKKEKDERILWKKNEVADYEATTFSIFYNNALFLTLIIVTSFYILRAFSPMVNYVFSVG 248
Q1HRN7        92 REDAVTREMTALL--ADDKKISRKEKDERILWKKNDVAEYEATTFSIFYNNALFLAVVIFASFYLLRSFTPTFNYILSMA 169 yellow fever mo...
OWR42219      92 REDAVAREMARKL--ADEKKMSRKEKDERILWKKNEVADYEATTFSIFYNNALFLTIVILASFYLLRSFTPTVNYIVSLT 169
XP_002131637  91 RSDGVAAELNAKMseSESKKISKKEKDERILWRKNEIAEAESMQLAVFYTNSLFLILLILSSFFFFKSYSPMPNYIISMV 170
CAP34679      87 RGPAVDREINTKF--ASDKKMTIKEKEERALFRKNEVADTESTYLSVFYTNTLFLTIMLISAFFLLANLAPVFNLLISTI 164
EFO20117      92 RSEAVTREMNRKL--ADDKKMSKKEKDERILWKKNEVGDYEATTFSIFWNNILFLSLLLILSFFLFASISSTFNCLFSMV 169

Q6DEU2       172 AASGLIALLSTG 183 tropical clawed frog
XP_001951873 172 IASGLIALFSTG 183
EDO39583     168 VAGGILALLSTG 179
XP_002066423 175 LASGALALFSTS 186
EEC13285     249 GAAGLLALFSTG 260
Q1HRN7       170 GASGLMALLSTG 181 yellow fever mosquito
OWR42219     170 VASGLLALLSTG 181
XP_002131637 171 GASSITGLLSTS 182
CAP34679     165 GSAALVAFLSTA 176
EFO20117     170 GAAGLVALFSTA 181
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