Conserved Protein Domain Family
PRK13805

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PRK13805: PRK13805 
bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional
Statistics
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PSSM-Id: 237515
Aligned: 353 rows
Threshold Bit Score: 1227.74
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
15674137   18 EKAAKFQEav------ayTDKLVKKAQAAVLKFEGYTQTQVDTIVAAMALAASKHSLELAHEAVNETGRGVVEDKDTKNH 91 
94967410   13 LSPERIAH----------LEGLVDNARAAASAFLQFTQEDVDRIVKQMVLAGMEHAQKLAQMAVEETMLGVLEDKVIKNM 82 
118619179  17 IDNLRTAE----------IDAIVDTAAEAARAFRKLDQQQVDAIVEAMVRAGVRAAGELAGVAIEETGFGVFEDKVVKNY 86 
169832183   4 DQAAVKKD----------IDDLVSRARNALEQFRGLGQERVDEIVRSAALAGLERHMELARMAVEETGRGVYEDKILKNL 73 
183984081  17 IDNLRTAE----------IDAIVDTAAEAARAFRKLDQQQVDAIVEAMVRAGVRAAGELAGVAIEETGFGVFEDKVVKNY 86 
220931059  12 KATKEKKEirkglkiedsINKLVERANEAARKFKDYDQEQVDRIVKKMALAANDKHIELAKMAHRETGMGVYEDKITKNL 91 
289579350  15 TEVKETTDvk------kqIDLLVERAKRAQEKLMSYTQEQIDEIVKVMALAGIEKHVELARLAHEETKMGVYEDKITKNL 88 
297545491  15 TEVKETTDvk------kqIDLLVERAKRAQEKFMSYTQEQIDEIVKVMALAGIEKHVELAKLAHEETKMGVYEDKITKNL 88 
302392706   8 IPRQPQEQ----------IFTLIDKALEAASQLDVMSQKELDRIIKEMALAGVDNHIRLAELAVEETEMGVYEDKITKNL 77 
304318035   6 METDVQKQ----------IDLLVSKAQEAQKKFMSYTQEQIDAIVKAMALAGVDKHVELAKLAYEETKMGVYEDKITKNL 75 
15674137   92 FASESVYNAIKNDKTVGVISENKVAGSVEIASPLGVLAGIVPTTNPTSTAIFKSLLTAKTRNAIVFAFHPQAQKFSSHAA 171
94967410   83 VATEFVYNYVKDKRTVGIIREYPERRLTEIAEPIGVIFSLIPITNPTSTVLFKCIMAIKTRNAVIFSPHPRAWRCCKEAV 162
118619179  87 VATEFLHDYLRGKKSVGVIDEDVEHNIVYVAEPIGVVLGITPVTNPTSTVLFKAIVAAKTRNAILFRPSPYAVRCCEQSI 166
169832183  74 YAVEYVYNSIRDRKTAGVVYEDPETGYREIAEPAGVIAALIPLTNPTSTTLFKGLIALKTRNPVVFSFHPGARRSSTAAA 153
183984081  87 VATEFLHDYLRGKKSVGVIDEDVEHNIVYVAEPIGVVLGITPVTNPTSTVLFKAIVAAKTRNAILFRPSPYAVRCCEQSI 166
220931059  92 FASEYVYNYLRDKKTAGILNKNIEENYIEVAEPIGVVAALTPVTNPTSTTIFKALICMKTRNPVIFSFHPRAMKCSIEAA 171
289579350  89 FAVEYVYNYIKDKKTVGILSENLEENYMEVAEPVGIISGVTPVTNPTSTTMFKCLIAIKTRNPIIFSFHPKALKCSIEAA 168
297545491  89 FAVEYVYNYIKDKKTVGILSENLEENHMEVAEPVGIIAGVTPVTNPTSTTMFKCLIAIKTRNPIIFSFHPKALKCSIEAA 168
302392706  78 FATENVYHDIKDKKTKGVINQDSTTGIIEVAEPVGVIAALIPATNPTSTALFKALIALKAGNPVIFSFHPRAFESSKETA 157
304318035  76 FATEYVYHDIKNEKTVGIINENIEENYMEVAEPIGVIAGVTPVTNPTSTTMFKCLISIKTRNPIIFSFHPKAIKCSIAAA 155
15674137  172 KIVYDAAIEAGAPEDFIQWIEVPSLDMTTALIQNRGLatILATGGPGMVNAALKSGNPSLGVGAGNGAVYVDATANIERA 251
94967410  163 HVMYEAARKHGAPDGVFACLESHNLDDNDYLMHHKYVsmIDATGGPSAVKAAYSSGKPALGVGAGNTPVYLEKTADINMA 242
118619179 167 EILRTAAEAAGMPPGALQVIPDAAHEVTHYLFKHPKVdfIWVTGGPKIVALANSAGKPGLSVGPGNAPIYIHKTADLKGA 246
169832183 154 EALLEGAVAAGAPPECLLWIEDPTVEAARTLMRHPGVnlILATGGTAMVRAAYSAGIPALGVGPGNVPCYIHRTAHLERA 233
183984081 167 EILRTAAEAAGMPPGALQVIPDAAHEVTHYLFKHPKVdfIWVTGGPKIVALANSAGKPGLSVGPGNAPIYIHKTADLKGA 246
220931059 172 RILKEAAIKAGAPENCISWIEEPSIEATNYLMKHPEVdlILATGGSGMVKAAYSSGKPALGVGPGNVPCYIEKTANIKQA 251
289579350 169 KTMYKAALKAGAPEGCIGWIETPSIEATQLLMTHPGVslILATGGAGMVKAAYSSGKPALGVGPGNVPCYIEKTANIKRA 248
297545491 169 KTMYEAALKAGAPEGCIGWIETPSIEATQLLMTHPGVslILATGGAGMVKAAYSSGKPALGVGPGNVPCYIEKTANIKRA 248
302392706 158 RIMRNAAIEAGAPEGCIQWIEPSSEEMTDKLMTHSDVslVLATGGGSMVQAAYSSGTPAIGVGPGNVPVYIEESADLEQA 237
304318035 156 KVMYEAALKAGAPEGCIGWIETPSIEATQLLMTHPGVslILATGGAGMVKSAYSSGKPALGVGPGNVPCYIEKSANIKRA 235
15674137  252 VEDLLLSKRFDNGMICATENSAVIDASVYDEFIAKMQEQGAYMVPKKDYKAIESFVFveragEGFGVTGPVAGRSGQWIA 331
94967410  243 VVDIITSKTFDNGTICASEQTVVIDDEIYDTVLKKFSDLGTHICNEGETELLGRTVId---pDTGAMQPMAVGQKAADIA 319
118619179 247 VVDILISKTFDSSVICPAKQTCIIDDEIYDEMIAEFERMGAQLLTADQAKAVAEFAFg----cGDKVSLDAVGQKAPELA 322
169832183 234 VTDLILSKTFDHGMICASEQALIVDRAVSNRVRELMEAAGCRFLNAGETRLLEQLATa---gRTCSLNPQIVGKSPVDIA 310
183984081 247 VVDILISKTFDSSVICPAEQTCIIDDEIYDEMIAEFERMGAQLLTADQAKAVAEFAFg----cGDKVSLDAVGQKAPELA 322
220931059 252 VSDLILSKTFDNGMICASEQAVVVDKEIAAEVKKFMQENGCYFVSKKESEKLARVAVd---qERGAMNPAVVGQPARKIA 328
289579350 249 VSDLILSKTFDNGTVCASEQAVIIDEEIANEVKKLMKEYGCYFLNKEETKKLEEFAId---kNTGLMNPAVVGQPAVKIA 325
297545491 249 VSDLILSKTFDNGTVCASEQAVIIDEEIANEVKKLMREYGCYFLNKEETKKLEEFAId---kNTGLMNPAVVGQPAVKIA 325
302392706 238 VHDITTSKTFDNGTVCASEQTLLVDKEVSSRVKELFVSYHTYILDEAERKRLEKVAId---sETKAMNPKVVGQSATKIA 314
304318035 236 VSDLILSKTFDNGVICASEQAVIIDEEIADEVKKLMKEYGCYFLNKDEIKKLEKFAId---eQSCAMSPAVVGQPATKIA 312
15674137  332 EQAGVKVPKDKDVLLFE-LDKKNI--GEALSSEKLSPLLSIYKAETREEGIEIVRSLLAYQGAGHNAAIQigAMDDPFVK 408
94967410  320 AAVGIEVQPKTKLIIAP-IKGVGP--NHPLSVEKLFPVLAVYRAHSTEEALDVCVAVNRAGGLGHTAVIF--SRNDDIIH 394
118619179 323 ARAGFSVPPTVKVPLAQlPSDLDElaAHPLVQEKLMPVLGVVRARSVQHGIDAAVLVTEHGGLGHTSAIY--ANDDDVIE 400
169832183 311 RMAGFEVPEDTKILVAV-QEGVGP--DHPLSREKLSPVLAFYVVGDTGAAIERAAEVVRYEGLGHTAVIH--AADREVIE 385
183984081 323 ARAGFSVPPTVKVLLAQlPSDLGElaAHPLVQEKLMPVLGVVRARSVQHGIDAAVLVTEHGGLGHTSAIY--ANDDDVIE 400
220931059 329 KMAGIKVPDDTKILVAE-LKGVGE--NYPLSREKLSPILGWYVVKDYREGIKRCEEITEFGGLGHSSVLH--SNDEKVID 403
289579350 326 QMAGFKVPENTKILVAE-YPAVGP--EYPLSREKLSPILALYTVKDYKEGIKRCEEMIQFGGLGHSAVIH--SEKQQIIN 400
297545491 326 QMAGFKVPENTKILVAE-YPAVGP--KYPLSREKLSPILALYTVKDYKEGIKRCEEMIQFGGLGHSAVIH--SENQQIIN 400
302392706 315 EMAGIEVPDDTVLLLVP-LQGIGA--GYPLSREKLSPILGVQEVADYREGIGKISEVVNFDGLGHTAVVH--SNCQQVID 389
304318035 313 EMADFKVPDGTKILVAE-YEGIGP--KYPLSREKLSPILACYTVKDYNEGIKKCEEMTEFGGLGHSAVIH--SENQDVIN 387
15674137  409 EYGEKVEASRILVNQPDSIGGVGDIYTdAMRPSLTLGTGSWGKNSLSHNLSTYDLLNVKTVAKRRNRPQWVRLPKEIYYE 488
94967410  395 RFGILLNAGRLIVNSPGSIGALGGVYN-DMVPTFSFGCGTGGGNSTMDNVNVYHYLNIKRLARRTPPSMWFRIPNQIYFN 473
118619179 401 AYGLAVRTGRILVNAPTAVGALGGVYN-NLTPTFSLGCGTWGGSSTTENVNYRQLLNIKTVSRRRTPPQWFRVPSNTYFN 479
169832183 386 SFSQRVPAGRIILNSPASQGALGDLYN-VLTPSLTLGCGYIGHNSTTDNVSAVHLVDIKRVAPRRAETQWFRVPPEIYFE 464
183984081 401 AYGLAVRTGRILVNAPTAVGALGGVYN-NLTPTFSLGCGTWGGSSTTENVNYRQLLNIKTVSRRRTPPQWFRVPSNTYFN 479
220931059 404 EFSRRLRTGRLIINSPSSQGAIGDMYN-FNVPSLTLGCGSMGKNSTTDNVNVDNLINKKRVAMRKERMKWVKVPPRIYFE 482
289579350 401 EFANRVQASRILVNAPASQGAIGDIYN-TATPSLTLGCGTMGGNSTTDNVSVYNLINIKRVFIRKERMKWFRVPPQIYFE 479
297545491 401 EFANRVQASRILVNAPASQGAIGDIYN-TATPSLTLGCGTMGGNSTTDNVSVYNLINIKRVFIRKERMKWFRVPPQIYFE 479
302392706 390 EFRTKVKTGRLLVNNPATFGAVGDIYN-HLPPSMTLGCGTFGGNSTTANVTVDQLYNVKRLTDRKVEREWIKLPPEIYFN 468
304318035 388 EFARRVRTGRLIVNSPSSQGAIGDIYN-TNTPSLTLGCGSMGRNSTTDNVSVNNLLNIKRVVIRKDRMKWFKIPPKIYFE 466
15674137  489 KNAISYLQELP-HVHKAFIVADPGMVKFGFVDKVLEQLAirPTQVETSIYGSVQPDPTLSEAIAIARQMKQFEPDTVICL 567
94967410  474 PNSIQNLAt-F-PTRSTVIVTNPPLEQMGHVDIVRRYI---PADTRIHVLVIPDCEPELKAVMDGVEALNFYKADQIIAL 548
118619179 480 EGALDNLREL--DCETVVVVTDALTEERGVVEALRGKLRa----qHVQVFSEVTPEPDETTIRRGVALMQRVQPDLLIAI 553
169832183 465 PGSLSLLSQMP-GLGRVFLVTDEVLAELGYVDRVRRHLEsrTEPVRLKVFSGVEPNPSLETVRRGTRRLGEFNPDTIIAL 543
183984081 480 EGALDNLREL--DCETVVVVTDALTEERGVVEALRGKLRa----qHVQVFSEVTPEPDETTIRRGVALMQRVQPDLLIAI 553
220931059 483 YGSLRYLS--GvRGERAFIITDKTMSQLGFIDKVEEHLS--VAGVQTRVFDSVEPDPSVETVLNGCQEMNEFKPDIIIAL 558
289579350 480 RGSIQYLSQV--KGKKAFIVTDPTMVKLGFVDKVTYQLD--KANIKYEIFSEVEPDPSVDTVEKGIKIMKEFEPDLLIAV 555
297545491 480 RGSIQYLS--QvKGKKAFIVTDPAMVKLGFVDKVTYQLD--KANIKYEIFSEVEPDPSVDTVEKGIKIMKEFEPDLLIAV 555
302392706 469 PGSLSQLS--NlEGEKAVIITDKVMEELGYVQQTAEYLE--QAEIDYQVFTGVEPDPSVTTVMEGKEVLEAYGADIIIAL 544
304318035 467 SGSLQYLCKV--KKKKAFIVTDPFMVKLGFVDKVTYQLD--KANIDYEIFSEVEPDPSVDTVMNGVKIMNSYNPDLIIAV 542
15674137  568 GGGSALDAGKIGRLIYEYDARgeadlsddaslkeLFQELAQKFVDIRKRIIKF--YHPHKAQMVAIPTTSGTGSEVTPFA 645
94967410  549 GGGSVIDAAKMMKLKYESPDA-------------NFEELGSPFLDLRKRVVQFptEKKHHARLIAVPTTSGTGSEVTPFA 615
118619179 554 GGGSVLDAGKAMRLFYEHPEK-------------SLDALTMPFLDPRKRVADYp-TDRHRIQLVAVPTTSGTGSEVSPAA 619
169832183 544 GGGSVIDAAKAMWLFHEYPEV-------------RFEHLKLKFTDIRKRTYRLp-ARPRKTRLVAVPTTSGSGSEVTAFA 609
183984081 554 GGGSVLDAGKAMRLFYEHPEK-------------SLDALTMPFLDPRKRVADYp-TDRHRIQLVAVPTTSGTGSEVSPAA 619
220931059 559 GGGSPMDAAKGMWLFYEHPET-------------RFEDLKMKFNDIRKRVYKFp-RLGKKATFIAVPTTSGTGSEVTAFS 624
289579350 556 GGGSAIDAAKGMWLFYEYPDT-------------KFEDLRLKFMDIRKRTYRFp-ELGKKALFIAIPTTSGTGSEVTAFA 621
297545491 556 GGGSAIDAAKGMWLFYEYPDT-------------KFEDLRLKFMDIRKRTYRFp-ELGKKALFIAIPTTSGTGSEVTAFA 621
302392706 545 GGGSPIDAAKGMWLFYEYPET-------------DFKDLKLRFMDIKKRVYDFp-ELGDKAKFVAIPTTSGSGSEITSFT 610
304318035 543 GGGSAIDAAKGMWLFYEYPDT-------------EFETLRLKFADIRKRAFKFp-ELGKKALFIAIPTTSGTGSEVTAFA 608
15674137  646 VITDDETHVKYPLADYQLTPQVAIVDPEFVMTVPKRTVSWSGIDAMSHALESYVSVMSSDYTKPISLQAIKLIFENLTES 725
94967410  616 VLFDKARQRKITLADYSLSPDVAIVDPQFVMSMPKGLTADTGIDCLTHALEAGVSNYASPYTDSNAMQAIRLAFKYLPIA 695
118619179 620 VLTVG--GKKETLVDYSLVPDLAIVDPVLTSSMPQKLTADIGIDALTHALEAIVSIFASPYTDALCAQAVRLIFDALPRA 697
169832183 610 VITDRDRDIKYPLADYALTPDVAIVDVDLAMGQPPALTADAGMDVLGHALEAYVSVRASDFTDPPAIKAIEAVFRYLPRA 689
183984081 620 VLTVG--GKKETLVDYSLVPDLAIVDPVLTSSMPQKLTADTGIDALTHALEAIVSIFASPYTDALCAQAVRLIFDALPRA 697
220931059 625 VITDKKRNIKYPLADYELTPDIAIIDPELVLTVPQSVTADTGLDVLTHAIEAYVSVMASDYTDALAEKAIKLVFEYLPRA 704
289579350 622 VITDKKRNIKYPLADYELTPDIAIIDSDFVMTIPPSVTADTGMDALTHAIEAYVSVMASDYTDALAEKAIKLIFEYLPKA 701
297545491 622 VITDKKKNIKYPLTDYELTPDIAIIDPDFVMTIPPSVTADTGMDALTHAIEAYVSVMASDYTDALAEKAIKLIFEYLPKA 701
302392706 611 VITDKENQVKYPLVSYELTPDMAIVDSELAMTLPPKMTAYTGLDVLTHGIEAYVSVMASDYTDPLALQAIKLVFEYLPRA 690
304318035 609 VITDKKRNIKYPLADYELTPDIAIIDPDLTKTVPPSVTADTGMDVLTHAIEAYVSVMASDYTDALAEKAIKLVFEYLPKA 688
15674137  726 YHYD-PAHptkegQKARENMHNAATLAGMAFANAFLGINHSLAHKIGGEFGLPHGLAIAIAMPHVIKFNAVTGNvKRTPY 804
94967410  696 YENP-QDE------EARNTMHNAATIAAIAFSNASVGLNHALAHAFGARFGVPHGRANALMLPHVIAFNAAVPQ-KFMPS 767
118619179 698 YDDP--DD-----LSARTSMSNAATLAGLAFSNAFVGTNHTLAHAVGAKFSVPHGRANGIFLPHVLRYNASLPT-KFMPA 769
169832183 690 YRNP--GD-----REAREKMHTAATLAGMAFTNAFLGVNHSLAHKLGNEFNLPHGRAVAVLMPHVIEYNAEVPA-KYASY 761
183984081 698 YDD--PDD-----LSARTSMSNAATLAGLAFSNAFVGTNHALAHAVGAKFSVPHGRANGIFLPHVLRYNASLPT-KFMPA 769
220931059 705 YKNGnDRE-------ARKKMHNASCIAGMAFTNAFLGLNHSMAHILGGKFHIPHGRANAILLPHVIRYNAGKPS-KLASF 776
289579350 702 YKNG--QD-----KVAREKLHNASCLAGMAFTNAFLGLNHGMAHILGAKFHLPHGRANAILLPYVIEYNAELPK-KFASF 773
297545491 702 YKNG--QD-----KVAREKMHNASCIAGMAFTNAFLGINHSMAHILGAKFHLPHGRANAILLPYVIEYNAELPK-KFASF 773
302392706 691 YKNG-TED-----KEAREKMHHAACIAGMSFTNAFLGINHSLAHVLGSKFEISHGLANALLLPHVIKYNAQSPT-KFAHY 763
304318035 689 YKNG--ND-----EVAREKMHNASCMAGMAFTNAFLGINHSMAHILGGKFHIPHGRANAILLPYVIKYNAEKPT-KFVAY 760
15674137  805 PRYETYRAQEDYAEISRFMGFAGKDDSDekAVQALVAELKKLTDSIDINITLSGNGVDKAHLERELDKLADLVYDDQCTP 884
94967410  768 PNQQGYVAHKKYAMIADLLGLPGHTVEE--KVASLITAVEELLDRLNLPRSIASMGIKREDFESAMPELVKAAFEDPSWL 845
118619179 770 PGYSAYIAPDKYAQLGQLVf-GGHLPDD--SRQRLFAGVDDLLDRLDMPRSLREFGVDEQGFLVALPTLAMTAFEDLSNR 846
169832183 762 PNYGYYRAAERYQEIARHLGLPASTAAE--GSAGLAETVRRLIAELDLPPTIAACGVPRDRFEARLALLAEKAYEDQTTV 839
183984081 770 PGYSAYIAPDKYAQLGQLVf-GGHLPDD--SRQRLFAGVDDLLDRLDMPRSLREFGVDEQEFLAALPTLAMTAFEDLSNR 846
220931059 777 PQYDYPRAGERYAEIARILGLPASTTEE--GVESLVKAITDLMRELNIPLSLEEAGVNHNKFEKELEDMADIAHNDQCTG 854
289579350 774 PQYEYPKAAEKYAEIAKFLGLPASTTDE--GVKSLIEAIKNLMKELNLPLTLKEAGINKEEFEKQIMEMADIAFNDQCTG 851
297545491 774 PQYEYPKAAEKYAEIAKFLGLPASTTDE--GVKSLIEAIKNLMKELNLPLTLKDAGINKEEFEKQIMEMADIAFNDQCTG 851
302392706 764 PNYSYHQAGERYNELAKELGLKADSREK--GVNNLIQEIKNLMITLDLPLSIAELEIDKQEFKSKIGAMAKIAYSDQATI 841
304318035 761 PQYEYPKAAERYAEIARFLGLPASTVEE--GVESLIEAIKNLMKELNIPLTLKDAGINKEQFEKEIDEMSDIAFNDQCTG 838
15674137  885 ANPRQPRIDEIKQLLLDQY 903
94967410  846 SNPRMPLMSELQELFLQAY 864
118619179 847 TNPRMPLVSEITDLLRLGY 865
169832183 840 TNPRQPLISELIALYRRAY 858
183984081 847 TNPRMPLVSEITDLLRLGY 865
220931059 855 TNPRMPLVNEIKEIYRQAY 873
289579350 852 SNPRMPLVSEIAEIYRKSY 870
297545491 852 SNPRMPLVSEIAEIYRKAY 870
302392706 842 ANPRKPLVSELEDIYNKAY 860
304318035 839 SNPRMPLTKEIAEIYRKAY 857
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