Conserved Protein Domain Family
Ag332

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pfam04671: Ag332 
Erythrocyte membrane-associated giant protein antigen 332
To date many different Plasmodium antigens recognized by the hyperimmune system human sera have been cloned, sequenced and characterized. The majority contain tandemly repeated amino acid sequences which make up a considerable portion of the protein sequence. It has been suggested that these repeat-containing antigens may provide an immunological 'smokescreen' to the parasite in order to evade the human immune system. This repeat is found exclusively in the Plasmodium falciparum Ag332 protein and occupies most of its length.
Statistics
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PSSM-Id: 309696
Aligned: 25 rows
Threshold Bit Score: 22.9512
Created: 26-Apr-2021
Updated: 29-Sep-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ETW41847       989 GSVSEEVLEeEGFGTEEFVgQQ 1010 Plasmodium falciparum NF135/5.C10
2_pfamImport     1 --VTEEIVE-DGLATDEFVeQQ 19  
13_pfamImport    1 GAVTEEIVQ-DGLITEEIL-EE 20  
14_pfamImport    1 GSVTEEIVE-EGSDTGEIVeEE 21  
16_pfamImport    1 GSDTEEILE-EGSFNEEIVeEE 21  
17_pfamImport    1 GSITEEIVE-DGSANEKIVeEE 21  
KOB63748      2411 GSATEEIVQ-DGSGTNDFVgKQ 2431 Plasmodium falciparum HB3
KOB63551      1479 lSGSEEVLE-DEWVTDAFMgQE 1499 Plasmodium falciparum HB3
KOB85466      2978 ESIIEEIVE-DGLTTDDLVgQQ 2998 Plasmodium falciparum Dd2
ETW30240        26 KSVNEEVVE-DGLTIDDFVgLQ 46   Plasmodium falciparum FCH/4
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