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Cover of Community Supports for People With Tuberculosis

Community Supports for People With Tuberculosis

CADTH Health Technology Review

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Key Messages

  • A limited literature search was conducted to identify evidence about the use of peer support workers, community support workers, or social workers to assist people with tuberculosis who are facing barriers and the types of interventions used by these workers.
  • Fourteen reports are included in this report that describe strategies used by support workers to engage people with tuberculosis who face barriers.
  • The interventions identified that support continued engagement and reduce attrition of people with tuberculosis focused on involving the clients in the decision-making process and overcoming potential hurdles to treatment. Strategies included culturally relevant education at all levels (e.g., worker, patient, family, community), referral to applicable programs or care, incentives, and enablers.

Context

Tuberculosis (TB) is a disease that disproportionately affects certain groups and communities in Canada, including people who are foreign-born and people who encounter specific social barriers (e.g., people experiencing homelessness, people who inject drugs).1 For these people, a less clinical approach to treatment may be required to promote engagement and prevent attrition. The use of support workers (e.g., peer support workers, community support workers, social workers) may be a strategy to help support care in people with TB who are facing barriers.

The purpose of this report is to identify and describe the strategies, and the evidence of their use, that support workers and allied health professionals use to facilitate completion of treatment protocols in people with TB who require additional assistance with care.

Research Questions

  1. What is the evidence to support the use of peer support workers, community support workers, or social workers to reduce the number of people with tuberculosis who face barriers and are lost to care?
  2. What interventions do support workers use to effectively maintain continued engagement of people with tuberculosis who face barriers and to reduce patient attrition from tuberculosis care?

Methods

This report is not a systematic review and does not involve critical appraisal or include a summary of study findings. Rather, it presents an annotated list of citations and a summary of the key components of TB programs and initiatives used by support workers and allied health professionals to engage populations and people with TB who face barriers to facilitate TB treatment. This report is not intended to provide recommendations for or against a particular intervention.

Literature Search Methods

A limited literature search was conducted by an information specialist on key resources, including MEDLINE, Cumulative Index to Nursing and Allied Health Literature (CINAHL), the Cochrane Database of Systematic Reviews, the International HTA Database, the websites of Canadian and major international health technology agencies, as well as a focused internet search. The search strategy comprised both controlled vocabulary, such as the National Library of Medicine’s MeSH (Medical Subject Headings), and keywords. The main search concepts were support workers and tuberculosis. No filters were applied to limit the retrieval by study type. If possible, retrieval was limited to the human population. The search was completed on November 11, 2022, and was limited to English-language documents published since January 1, 2017.

Selection Criteria and Methods

One reviewer screened literature search results (titles and abstracts) and selected publications according to the inclusion criteria presented in Table 1. Open-access, full-text versions of guidelines, guidance documents, and program evaluations were reviewed when available and the relevant information was summarized; otherwise, full-text publications were not reviewed.

Table 1. Selection Criteria.

Table 1

Selection Criteria.

Exclusion Criteria

Articles were excluded if they did not meet the selection criteria outlined in Table 1, they were duplicate publications, or were published before 2017. Reports focused on screening and diagnosis of TB and contact tracing were also excluded. If articles reported on included and excluded topics (e.g., strategies used to encourage people who face barriers to complete screening and treatment for TB), the article was included but the excluded topic(s) were not summarized. Additional references of potential interest that did not meet the inclusion criteria are provided in Appendix 1.

Overall Summary

Fourteen relevant references about the strategies used by peer support workers, community support workers, or social workers to engage their clients with TB who face barriers were identified for this report.2-15 Guidance describing engagement with people with TB by TB programs were published in reports from Canada,2-5 the UK,8-10 Europe,6,12,13 and globally.7,11 A retrospective cohort study and a descriptive survey study were from the UK14 and Europe,15 respectively.

The information included in this report covered people diagnosed with TB requiring assistance with care from several specific populations, including people who:

  • are foreign-born or seeking asylum
  • are experiencing homelessness or unstable housing
  • have an alcohol use or a substance use disorder
  • inject drugs
  • need mental health support
  • are in contact with the criminal justice system
  • have known or suspected nonadherence to TB treatment.

The types of support workers and allied health professionals identified included:

  • district and provincial TB coordinator
  • social worker, case worker, outreach worker
  • community health worker, cultural link worker, employee or volunteer from an allied organization or initiative
  • alcohol, drug, or substance use counsellor
  • mental health counsellor, therapist
  • peer counsellor, community champion, religious or spiritual leader
  • prison staff or immigration removal centre staff
  • pharmacist, pharmacy technician
  • primary care receptionist
  • interpreter.

The major themes of support identified included:

  • Address the stigma surrounding TB diagnosis through patient, community, and health care and allied health care worker education.
  • Identify the basic social, mental, and health needs of a person with TB and connect them with appropriate and culturally relevant resources or referrals (e.g., enrolling a client with a primary care physician, referral to mental health services, coordinating housing arrangements).
  • Involve the person with TB in decision-making and developing their own care plan.
  • Help to ease the person with TB through the entire duration of their treatment course through the use of incentives and enablers. This includes reassuring the client that any financial, legal, or social costs are minimized or eliminated.
    • Incentives can be monetary or material (e.g., cash, food vouchers, clothing).
    • Enablers can be anything that directly or indirectly helps a person with TB access treatment (e.g., directly observing therapy in the home, accompanying their clients to appointments, providing bus tickets or childcare).
  • Liaise with organizations with aligned mandates (e.g., serve the same population).

Annotated Reference List

A total of 14 reports were included in the current report. Guidance documents, including evidence- and consensus-based guidelines and synthesis reports, are summarized in Table 2. Nonrandomized studies are summarized in Table 3. Further details can be found by consulting the individual article citations.

Table 2. Summary of Included Guidance Documents.

Table 2

Summary of Included Guidance Documents.

Table 3. Summary of Included Nonrandomized Studies.

Table 3

Summary of Included Nonrandomized Studies.

References

1.
Chapter 13: Canadian Tuberculosis Standards 7th Edition: 2014 – Tuberculosis surveillance and screening in selected high-risk populations. Ottawa (ON): Public Health Agency of Canada; 2014: https://www​.canada.ca​/en/public-health/services​/infectious-diseases​/canadian-tuberculosis-standards-7th-edition​/edition-9.html. Accessed 2022 Dec 13.
2.
Cooper R, Houston S, Hughes C, Johnston JC. Chapter 10: Treatment of active tuberculosis in special populations. Can J Respir Crit. 2022;6(Sup 1):149-166.
3.
Greenaway G, Diefenbach-Elstob T, Schwartzman K, et al. Chapter 13: Tuberculosis surveillance and tuberculosis infection testing and treatment in migrants. Can J Respir Crit. 2022;6(Sup 1):194-204.
4.
Heffernan C, Haworth-Brockman M, Plourde P, Wong T, Ferrara G, R L. Chapter 15: Monitoring tuberculosis program performance. Can J Respir Crit. 2022;6(Sup 1):229-241.
5.
Johnston JC, Cooper R, Menzies D. Chapter 5: Treatment of tuberculosis disease. Can J Respir Crit. 2022;6(Sup 1):66-76.
6.
Nazareth J, Baggaley RF, Divall P, et al. What is the evidence on existing national policies and guidelines for delivering effective tuberculosis, HIV and viral hepatitis services for refugees and migrants among Member States of the WHO European Region? . (Health Evidence Network (HEN) synthesis report 74). Copenhagen (Denmark): World Health Organization; 2021: https://apps​.who.int​/iris/bitstream/handle​/10665/352055/9789289056526-eng.pdf. Accessed 2022 Nov 21. [PubMed: 35263069]
7.
Psychosocial counselling and treatment adherence support for people affected by tuberculosis. London (UK): International Union Against Tuberculosis and Lung Disease; 2021: https://www​.thetruthabouttb​.org/wp-content​/uploads/2021/04/Psychosocial-Single-Pages.pdf. Accessed 2022 Nov 24.
8.
Tuberculosis NICE guideline NG33. London (UK): National Institute for Health and Care Excellence; 2019: https://www​.nice.org​.uk/guidance/ng33/chapter​/Recommendations. Accessed 2022 Nov 2022. [PubMed: 31869029]
9.
Tackling Tuberculosis in Under-Served Populations: A Resource for TB Control Boards and their partners. London (UK): Public Health England; 2019: https://assets​.publishing​.service.gov.uk​/government/uploads/system​/uploads/attachment_data​/file/773730​/Tackling_TB_in_Under-Served​_Populations​_-_a_Resource_for_TBCBs_and_partners​.pdf. Accessed 2022 Nov 24. [PubMed: 29509909]
10.
TB Information for prisons and immigration removal centre staff. London (UK): Public Health England; 2019: https://assets​.publishing​.service.gov.uk​/government/uploads/system​/uploads/attachment_data​/file/851865​/RA_TB_Prison_leaflet.pdf. Accessed 2022 Nov 22.
11.
Dlodlo RA, Brigden G, Heldal E, et al. Management of Tuberculosis: a Guide to Essential Practice. Paris (France): International Union Against Tuberculosis and Lung Disease; 2019: https://theunion​.org​/sites/default/files​/2020-08/TheUnion_Orange_2019.pdf. Accessed 2022 Nov 21.
12.
Migliori GB, Sotgiu G, Rosales-Klintz S, al e. ERS/ECDC Statement: European Union standards for tuberculosis care, 2017 update. Eur Respir J. 2018;51:1702678. [PubMed: 29678945]
13.
Hargreaves S, Rustage K, Nellums LB, et al. What constitutes an effective and efficient package of services for the prevention, diagnosis, treatment and care of tuberculosis among refugees and migrants in the WHO European Region? (Health Evidence Network (HEN) synthesis report 56). Copenhagen (Denmark): World Health Organization; 2018: https://www​.euro.who​.int/__data/assets/pdf_file​/0003/371145/who-hen-report-56​.pdf. Accessed 2022 Nov 22. [PubMed: 30091870]
14.
Izzard A, Wilders S, Smith C, et al. Improved treatment completion for tuberculosis patients: The case for a dedicated social care team. Vol 82. Philadelphia, Pennsylvania: W B Saunders; 2021:e1-e3. [PubMed: 33359406]
15.
Jansen-Aaldring N, van de Berg S, van den Hof S. Patient support during treatment for active tuberculosis and for latent tuberculosis infection: Policies and practices in European low-incidence countries. J Adv Nurs. 2018;74(12):2755-2765. [PubMed: 29964334]

Appendix 1. References of Potential Interest

    Previous CADTH Reports

    1. Tuberculosis Stigma and Racism, Colonialism, and Migration: A Rapid Qualitative Review. Ottawa (ON): CADTH. 2021. https://www​.cadth.ca​/tuberculosis-stigma-and-racism-colonialism-and-migration-rapid-qualitative-review Accessed 2022 Nov 22. [PubMed: 34260166]
    2. Direct Observational Therapy for the Treatment of Tuberculosis: A Review of Clinical Evidence and Guidelines. Ottawa (ON): CADTH. 2020. https://www​.cadth.ca​/sites/default/files​/pdf/htis/2020/RC1312​%20DOT%20for%20TB%20Final.pdf Accessed 2022 Nov 22. [PubMed: 33523614]
    3. Management of Discontinued Treatment for Tuberculosis: Guidelines. Ottawa (ON): CADTH. 2020. https://www​.cadth.ca​/sites/default/files​/pdf/htis/2020/RB1516​%20TB%20discontinued%20Tx%20Final.pdf Accessed 2022 Nov 22.
    4. Prevention of Tuberculosis Reactivation: Clinical Utility and Guidelines. Ottawa (ON): CADTH. 2020. https://www​.cadth.ca​/prevention-tuberculosis-reactivation-clinical-utility-and-guidelines Accessed 2022 Nov 22.
    5. Support Programs for Tuberculosis Treatment: Clinical Utility and Guidelines. Ottawa (ON): CADTH. 2020. https://www​.cadth.ca​/sites/default/files​/pdf/htis/2020/RB1514​%20TB%20Support%20Programs%20Final.pdf Accessed 2022 Nov 22.
    6. Supports to Enhance Adherence to the Treatment of Latent Tuberculosis Infection. Ottawa (ON): CADTH. 2020. https://www​.cadth.ca​/sites/default/files​/hta-he/ht0033-tuberculosis-policy-insights-final.pdf Accessed 2022 Nov 22.
    7. Treatment of Tuberculosis: A Review of Guidelines. Ottawa (ON): CADTH. 2020. https://www​.cadth.ca​/sites/default/files​/pdf/htis/2020/RC1237​%20TB%20treatment%20guidelines%20Final​.pdf Accessed 2022 Nov 22.
    8. Interventions for the Treatment or Management of Tuberculosis: Clinical Effectiveness and Guidelines. Ottawa (ON): CADTH. 2019. https://www​.cadth.ca​/sites/default/files​/pdf/htis/2019/RA1045​%20TB%20Treatment%20Final.pdf Accessed 2022 Nov 22.

    Systematic Reviews

      Alternative Population: People Being Screened for Tuberculosis

      1. Hamilton K, Tolfree R, Mytton J. A systematic review of active case-finding strategies for tuberculosis in homeless populations. Int J Tuberc Lung Dis. 2018; 22(10): 1135-1144. [PubMed: 30236180]
      2. Heuvelings CC, Greve PF, de Vries SG, et al. Effectiveness of service models and organisational structures supporting tuberculosis identification and management in hard-to-reach populations in countries of low and medium tuberculosis incidence: a systematic review. BMJ Open. 2018; 8(9): e019642. [PMC free article: PMC6129047] [PubMed: 30196265]

      Unclear Population: People Diagnosed With Tuberculosis Requiring Assistance With Care Not Specified

      1. Law S, Daftary A, O'Donnell M, Padayatchi N, Calzavara L, Menzies D. Interventions to improve retention-in-care and treatment adherence among patients with drug-resistant tuberculosis: a systematic review. Eur Respir J. 2019; 53(1): 01. [PubMed: 30309972]
      2. Liu Y, Birch S, Newbold KB, Essue BM. Barriers to treatment adherence for individuals with latent tuberculosis infection: A systematic search and narrative synthesis of the literature. Int J Health Plann Manage. 2018; 33(2): e416-e433. [PubMed: 29431235]

    Non-Randomized Studies

      Alternative Location: US

      1. Hovell MF, Schmitz KE, Blumberg EJ, Hill L, Sipan C, Friedman L. Lessons learned from two interventions designed to increase adherence to LTBI treatment in Latino youth. Contemp Clin Trials Commun. 2018; 12: 129-136. [PMC free article: PMC6234503] [PubMed: 30456327]

      Alternative Location: Belarus

      1. Harrison RE, Shyleika V, Falkenstein C, et al. Patient and health-care provider experience of a person-centred, multidisciplinary, psychosocial support and harm reduction programme for patients with harmful use of alcohol and drug-resistant tuberculosis in Minsk, Belarus. BMC Health Serv Res. 2022; 22(1): 1217. [PMC free article: PMC9523183] [PubMed: 36180873]

      Unclear Intervention: Support Workers Not Specified

      1. Bedingfield N, Lashewicz B, Fisher D, King-Shier K. Systems of support for foreign-born TB patients and their family members. Public health action. 2022; 12(2): 79-84. [PMC free article: PMC9176195] [PubMed: 35734012]
      2. Thomas D, Summers RH. Patients' perceptions and experiences of directly observed therapy for TB. British Journal of Nursing. 2022; 31(13): 680-689. [PubMed: 35797082]
      3. Kim H, Choi H, Yu S, et al. Impact of Housing Provision Package on Treatment Outcome Among Homeless Tuberculosis Patients in South Korea. Asia Pac J Public Health. 2019; 31(7): 603-611. [PubMed: 31522517]

    Additional References

      Research Program: Alternative Population — People Being Screened for Tuberculosis (Unclear Intervention, Support Workers Not Specified)

      1. Story A, Garber E, Aldridge RW, et al. Management and control of tuberculosis control in socially complex groups: a research programme including three RCTs. NIHR Journals Library. 2020; 10. [PubMed: 33119243]

      Guidance Document: Alternative Population — First Nations Communities

      1. First Nations Health Authority Tuberculosis Services Community Programming Guide. West Vancouver (BC): First Nations Health Authority. https://www​.fnha.ca/WellnessSite​/WellnessDocuments​/FNHA-Tuberculosis-Services-Community-Program-Guide.pdf Accessed 2022 Nov 22.
        Refer to TB Wellness Champions on pages 10, 15, and 16.

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