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Bookshelf ID: NBK591121PMID: 37094054
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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 1373715-00-4
Drug Levels and Effects
Summary of Use during Lactation
No information is available on the clinical use of luspatercept during breastfeeding. Because luspatercept is a large protein molecule with a molecular weight of 76,000 Da, the amount in milk is likely to be very low. It is also likely to be partially destroyed in the infant's gastrointestinal tract and absorption by the infant is probably minimal. Until more data become available, the manufacturer recommends that breastfeeding be discontinued during luspatercept therapy and for 3 months after the last dose.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Substance Identification
Substance Name
Luspatercept
CAS Registry Number
1373715-00-4
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