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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 78919-13-8
Drug Levels and Effects
Summary of Use during Lactation
No information is available on the use of iloprost during breastfeeding. The half-life of iloprost is 20 to 30 minutes and iloprost is generally not detectable in plasma 30 to 60 minutes after inhalation. It is unlikely that clinically important amounts of iloprost are excreted into milk after 1 hour following an inhaled dose.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Substance Identification
Substance Name
Iloprost
CAS Registry Number
78919-13-8
Drug Class
Breast Feeding
Milk, Human
Cardiovascular Agents
Prostaglandins, Synthetic
Vasodilator Agents
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
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- Digital Tracking of Physical Activity, Heart Rate, and Inhalation Behavior in Patients With Pulmonary Arterial Hypertension Treated With Inhaled Iloprost: Observational Study (VENTASTEP).[J Med Internet Res. 2021]Digital Tracking of Physical Activity, Heart Rate, and Inhalation Behavior in Patients With Pulmonary Arterial Hypertension Treated With Inhaled Iloprost: Observational Study (VENTASTEP).Stollfuss B, Richter M, Drömann D, Klose H, Schwaiblmair M, Gruenig E, Ewert R, Kirchner MC, Kleinjung F, Irrgang V, et al. J Med Internet Res. 2021 Oct 8; 23(10):e25163. Epub 2021 Oct 8.
- Prevention of heparin-induced thrombocytopenia during open heart surgery with iloprost (ZK36374).[Surgery. 1987]Prevention of heparin-induced thrombocytopenia during open heart surgery with iloprost (ZK36374).Addonizio VP Jr, Fisher CA, Kappa JR, Ellison N. Surgery. 1987 Nov; 102(5):796-807.
- Efficacy of iloprost (ZK36374) versus aspirin in preventing heparin-induced platelet activation during cardiac operations.[J Thorac Cardiovasc Surg. 1987]Efficacy of iloprost (ZK36374) versus aspirin in preventing heparin-induced platelet activation during cardiac operations.Kappa JR, Horn MK 3rd, Fisher CA, Cottrell ED, Ellison N, Addonizio VP Jr. J Thorac Cardiovasc Surg. 1987 Sep; 94(3):405-13.
- Review Inhaled iloprost for therapy in pulmonary arterial hypertension.[Expert Rev Respir Med. 2011]Review Inhaled iloprost for therapy in pulmonary arterial hypertension.Ewert R, Gläser S, Bollmann T, Schäper C. Expert Rev Respir Med. 2011 Apr; 5(2):145-52.
- Review lloprost delivered via the BREELIB(TM) nebulizer: a review of the clinical evidence for efficacy and safety.[Ther Adv Respir Dis. 2019]Review lloprost delivered via the BREELIB(TM) nebulizer: a review of the clinical evidence for efficacy and safety.Gessler T. Ther Adv Respir Dis. 2019 Jan-Dec; 13:1753466619835497.
- Iloprost - Drugs and Lactation Database (LactMed®)Iloprost - Drugs and Lactation Database (LactMed®)
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