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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 15678-91-8
Drug Levels and Effects
Summary of Use during Lactation
Information in this record refers to the use of krypton Kr 81m as a diagnostic agent. The International Commission on Radiological Protection and other experts state that breastfeeding need not be interrupted after administration of krypton Kr 81m gas.[1][2]
Drug Levels
Krypton 81m is an inert gas that is a gamma emitter with a principal photon energy of 0.19 MeV. Because of its rapid decay, the effective half-time of lung elimination is equal to the physical half-life of 13.1 seconds. Peripheral krypton 81m radioactivity is exhaled after the first passage through the lungs
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
References
- 1.
- Parker JA, Coleman RE, Grady E et al. SNM practice guideline for lung scintigraphy 4.0. J Nucl Med Technol. 2012;40:57-65. [PubMed: 22282651]
- 2.
- Mattsson S, Johansson L, Leide Svegborn S et al. Radiation dose to patients from radiopharmaceuticals: A compendium of current information related to frequently used substances. Annex D. Recommendations on breast-feeding interruptions. Ann ICRP. 2015;44 (2 Suppl):319-21. [PubMed: 26069086]
Substance Identification
Substance Name
Krypton Kr 81m
CAS Registry Number
15678-91-8
Drug Class
- Breast Feeding
- Radiopharmaceuticals
- Krypton Radioisotopes
- Diagnostic Agents
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
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- Ventilation studies with krypton-81m.[Thorac Cardiovasc Surg. 1979]Ventilation studies with krypton-81m.Georgi P, Vogt-Moykopf I, Helus F, Ostertag H. Thorac Cardiovasc Surg. 1979 Dec; 27(6):359-61.
- Limitations of Kr-81m for quantitation of ventilation scans.[J Nucl Med. 1982]Limitations of Kr-81m for quantitation of ventilation scans.Modell HI, Graham MM. J Nucl Med. 1982 Apr; 23(4):301-5.
- Krypton-81m ventilation and technetium-99m macroaggregated albumin perfusion scintigraphy for detection of pulmonary embolism: the first experience in Taiwan.[Zhonghua Yi Xue Za Zhi (Taipei...]Krypton-81m ventilation and technetium-99m macroaggregated albumin perfusion scintigraphy for detection of pulmonary embolism: the first experience in Taiwan.Cherng SC, Yang SP, Wang YF, Jen TK, Huang WS, Lo AR. Zhonghua Yi Xue Za Zhi (Taipei). 2000 Dec; 63(12):876-84.
- Review Xenon Xe 133.[Drugs and Lactation Database (...]Review Xenon Xe 133.. Drugs and Lactation Database (LactMed®). 2006
- Review Experimental approaches to myocardial function studies: C15 O2 and 81m Kr.[Semin Nucl Med. 1977]Review Experimental approaches to myocardial function studies: C15 O2 and 81m Kr.Polcyn RE, Nickles RJ. Semin Nucl Med. 1977 Jan; 7(1):101-5.
- Krypton Kr 81m - Drugs and Lactation Database (LactMed®)Krypton Kr 81m - Drugs and Lactation Database (LactMed®)
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