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Labor Dystocia

Comparative Effectiveness Review, No. 226

Investigators: , M.D., M.P.H., , Ph.D., , M.D., Ph.D., , M.D., M.P.H., , Ph.D., M.S.P.H., , Ph.D., , M.D., M.H.Sc., , M.D., , D.P.T, Ph.D., , Pharm.D., J.D., , Ph.D., , Ph.D., , B.A., , M.S.L.S., , B.A., and , Ph.D.

Rockville (MD): Agency for Healthcare Research and Quality (US); .
Report No.: 20-EHC007

Structured Abstract

Objectives:

This review evaluates the comparative effectiveness of different strategies for treating labor dystocia in women with otherwise uncomplicated pregnancies.

Data sources:

We searched PubMed®, Embase®, CINAHL®, and the Cochrane Database of Systematic Reviews (CDSR), limiting the searches to studies in the English language and comparative studies published from January 1, 2005, to February 15, 2019.

Review methods:

Two investigators screened each abstract and full-text article for inclusion, abstracted data, rated quality and applicability, and graded evidence. When possible, random-effects models were used to compute summary estimates of effects.

Results:

Our review included 167 articles (158 unique studies). Studies included 25 relevant to defining abnormal labor, 12 relevant to amniotomy, 75 relevant to supportive care measures, 25 relevant to epidural analgesia, 1 relevant to cervical examination, 1 relevant to intrauterine pressure catheters, 17 relevant to high-dose versus low-dose oxytocin protocols, 1 relevant to fetal monitoring strategies, and 7 relevant to timing of pushing in the second stage. Evidence suggests that the duration and pattern of “normal” labor progress based on modern management are quite different from historical data, and that labor progress differs between nulliparous and parous women. Use of partograms did not change important maternal or neonatal outcomes, although the applicability of this evidence to modern U.S. settings is limited. Routine amniotomy decreased the total duration of labor in nulliparous women without affecting other outcomes (moderate strength of evidence [SOE]); routine amniotomy with oxytocin augmentation decreased labor duration without increasing cesarean delivery (high SOE). Although supportive care is considered to improve parental satisfaction with the birthing process, satisfaction outcomes were rarely assessed in the included clinical trials. An existing systematic review of 11 studies found that women receiving continuous emotional support were less likely to rate their birth experience negatively. Of the different types of supportive therapies, only emotional support interventions showed reductions in cesarean (low SOE for doula support, moderate SOE for continuous emotional support) and instrumental deliveries (moderate SOE). For women choosing analgesia (epidural vs. combined spinal epidural, or epidural vs. patient-controlled intravenous analgesia), neither type nor timing affected cesarean delivery rates (moderate SOE).

Conclusions:

The normal progress of labor given current practice is quite different from that originally described, although there is still uncertainty about the duration of “normal” labor in the absence of augmentation. Further work is needed to identify (1) the cesarean delivery rate that optimally balances maternal and neonatal outcomes and patient preferences, and (2) the best strategies to achieve this rate.

Contents

Prepared for: Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services, 5600 Fishers Lane, Rockville, MD 20857; www.ahrq.gov Contract No. 290-2015-00004-I Prepared by: Duke Evidence-based Practice Center, Durham, NC

Suggested citation:

Myers ER, Sanders GD, Coeytaux RR, McElligott KA, Moorman PG, Hicklin K, Grotegut C, Villers M, Goode A, Campbell H, Befus D, McBroom AJ, Davis JK, Lallinger K, Fortman R, Kosinski A. Labor Dystocia. Comparative Effectiveness Review No. 226. (Prepared by the Duke Evidence-based Practice Center under Contract No. 290-2015-00004-I.) AHRQ Publication No. 29-EHC007. Rockville, MD: Agency for Healthcare Research and Quality; May 2020. DOI: https://doi.org/10.23970/AHRQEPCCER226. Posted final reports are located on the Effective Health Care Program search page.

This report is based on research conducted by the Duke Evidence-based Practice Center under contract to the Agency for Healthcare Research and Quality (AHRQ), Rockville, MD (Contract No. 290-2015-00004-I). The findings and conclusions in this document are those of the authors, who are responsible for its contents; the findings and conclusions do not necessarily represent the views of AHRQ. Therefore, no statement in this report should be construed as an official position of AHRQ or of the U.S. Department of Health and Human Services.

None of the investigators have any affiliations or financial involvement that conflicts with the material presented in this report.

The information in this report is intended to help healthcare decision makers—patients and clinicians, health system leaders, and policymakers, among others—make well-informed decisions and thereby improve the quality of healthcare services. This report is not intended to be a substitute for the application of clinical judgment. Anyone who makes decisions concerning the provision of clinical care should consider this report in the same way as any medical reference and in conjunction with all other pertinent information, i.e., in the context of available resources and circumstances presented by individual patients.

This report is made available to the public under the terms of a licensing agreement between the author and the Agency for Healthcare Research and Quality. This report may be used and reprinted without permission except those copyrighted materials that are clearly noted in the report. Further reproduction of those copyrighted materials is prohibited without the express permission of copyright holders.

AHRQ or U.S. Department of Health and Human Services endorsement of any derivative products that may be developed from this report, such as clinical practice guidelines, other quality enhancement tools, or reimbursement or coverage policies, may not be stated or implied.

This report may periodically be assessed for the currency of conclusions. If an assessment is done, the resulting surveillance report describing the methodology and findings will be found on the Effective Health Care Program website at www.effectivehealthcare.ahrq.gov. Search on the title of the report.

Bookshelf ID: NBK557137PMID: 32479038

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