Berotralstat

Publication Details

Estimated reading time: 1 minute

CASRN: 1809010-50-1

image 427540787 in the ncbi pubchem database

Drug Levels and Effects

Summary of Use during Lactation

Berotralstat is a plasma kallikrein inhibitor indicated for prophylaxis to prevent attacks of hereditary angioedema. No information is available on the excretion of berotralstat into breastmilk. Because berotralstat is about 99% bound to plasma proteins, the amounts in milk are likely to be very low. If berotralstat is required by the mother, it is not a reason to discontinue breastfeeding. Until more data become available, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

C1-esterase inhibitor

Substance Identification

Substance Name

Berotralstat

CAS Registry Number

1809010-50-1

Drug Class

Breast Feeding

Lactation

Milk, Human

Serine Proteinase Inhibitors

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