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Bookshelf ID: NBK571316PMID: 34165943
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 2171511-58-1
Drug Levels and Effects
Summary of Use during Lactation
No information is available on the clinical use of amivantamab during breastfeeding. Because amivantamab is a large protein molecule with a molecular weight of 148,000 Da, the amount in milk is likely to be very low. It is also likely to be partially destroyed in the infant's gastrointestinal tract and absorption by the infant is probably minimal. The manufacturer recommends avoiding breastfeeding during amivantamab use and for 3 months after the last dose.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Substance Identification
Substance Name
amivantamab
CAS Registry Number
2171511-58-1
Drug Class
Breast Feeding
Lactation
Milk, Human
Antineoplastic Agents, Immunological
Antibodies, Bispecific
Antibodies, Monoclonal
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