Figure 35 displays a forest plot for the network meta-analysis reporting discontinuations due to adverse events in studies comparing Non-TNF biologics with Non-TNF biologics. Two comparisons were used in this analysis. Study-level data used in this Figure are presented in Appendix C. This figure is described further in the KQ3 Results section “Non-TNF vs. Non-TNF” as follows: “Discontinuations due to adverse events were only higher for TCZ plus MTX than ABA plus MTX (RR, 4.25; 95% CI, 2.07 to 8.72)”.

Figure 35Forest plot for network meta-analysis of discontinuations due to adverse events: Non-TNF versus non-TNF

95% CI = 95% confidence interval; MTX = methotrexate; RR = relative risk; TNF = tumor necrosis factor; vs. = versus.

From: Results

Cover of Drug Therapy for Early Rheumatoid Arthritis: A Systematic Review Update
Drug Therapy for Early Rheumatoid Arthritis: A Systematic Review Update [Internet].
Comparative Effectiveness Review, No. 211.
Donahue KE, Gartlehner G, Schulman ER, et al.
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