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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.

Brinzolamide

Last Revision: September 20, 2021.

Estimated reading time: 1 minute

CASRN: 138890-62-7

image 135028809 in the ncbi pubchem database

Drug Levels and Effects

Summary of Use during Lactation

No information is available on the use of brinzolamide ophthalmic drops during breastfeeding. French guidelines recommend ophthalmic carbonic anhydrase inhibitor drops such as brinzolamide as a preferred therapy for glaucoma during breastfeeding.[1] To substantially diminish the amount of drug that reaches the breastmilk after using eye drops, place pressure over the tear duct by the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Acetazolamide, Dorzolamide

References

1.
Blumen-Ohana E, Sellem E. J Fr Ophtalmol. 2020;43:63–6. [Pregnancy & glaucoma: SFO-SFG recommendations] [PubMed: 31813552]

Substance Identification

Substance Name

Brinzolamide

CAS Registry Number

138890-62-7

Drug Class

Breast Feeding

Lactation

Antiglaucoma Agents

Carbonic Anhydrase Inhibitors

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Copyright Notice

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Bookshelf ID: NBK501679PMID: 30000739