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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 133-67-5
Drug Levels and Effects
Summary of Use during Lactation
No information is available on the amount of trichlormethiazide in breastmilk. Intense diuresis with large doses may decrease breastmilk production. Other diuretics in low doses are preferred over trichlormethiazide.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information on trichlormethiazide was not found as of the revision date. Intense diuresis with thiazides and thiazide-like diuretics, fluid restriction and breast binding have been used to suppress postpartum lactation.[1-3] The added contribution of the diuretic to these measures, which are effective in suppressing lactation, has not been studied. There are no data on the effects of diuretics on established, ongoing lactation.
Alternate Drugs to Consider
References
- 1.
- Healy M. Suppressing lactation with oral diuretics. Lancet. 1961;1:1353–4.
- 2.
- Stout G. Suppression of lactation. Br Med J 1962;1:1150. Letter. PMC1958377.
- 3.
- Reiher KH. Zentralbl Gynakol. 1963;85:188–90. [Suppression of lactation by stimulation of diuresis] [PubMed: 13973786]
Substance Identification
Substance Name
Trichlormethiazide
CAS Registry Number
133-67-5
Drug Class
Breast Feeding
Lactation
Antihypertensive Agents
Thiazide Diuretics
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.