Fibrous dysplasia (FD)

A. FD of the proximal femur demonstrating the typical "ground-glass" appearance with a coxa vara ("shepherd's crook") deformity

B. 3D reconstructed CT of a man age 26 years with craniofacial FD and uncontrolled growth hormone excess, leading to macrocephaly and severe facial deformity

C. CT of a girl age ten years, demonstrating the typical "ground-glass" appearance of craniofacial FD in younger individuals. The optic canals are typically encased in FD (white arrows) without any visual disturbance.

D. CT of a woman age 40 years, demonstrating typical features of craniofacial FD in an older individual, including a more sclerotic appearance with mixed solid and cystic components. Optic nerves are encased in FD (white arrows) without visual disturbance.

E. Technetium-99 bone scintigraphy, posterior-anterior and anterior-posterior views (left and right panels, respectively), demonstrating patchy tracer uptake at affected skeletal sites, including the skull, ribs, femur, and tibia (arrows), consistent with a mosaic pattern of expression