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Items: 3

Select item 84615411.

Pemigatinib for previously treated, locally advanced or metastatic cholangiocarcinoma: a multicentre, open-label, phase 2 study

Prof Ghassan K Abou-Alfa, Vaibhav Sahai, Antoine Hollebecque, Gina Vaccaro, Davide Melisi, Raed Al-Rajabi, Andrew S Paulson, Mitesh J Borad, David Gallinson, Adrian G Murphy, Prof Do-Youn Oh, Efrat Dotan, Daniel V Catenacci, Prof Eric Van Cutsem, Tao Ji, Christine F Lihou, Huiling Zhen, Luis Féliz, Prof Arndt Vogel

Lancet Oncol. Author manuscript; available in PMC 2021 Sep 24.

Published in final edited form as: Lancet Oncol. 2020 May; 21(5): 671–684. Published online 2020 Mar 20. doi: 10.1016/S1470-2045(20)30109-1

PMCID:: PMC8461541

Abstract Article PDF–1.5M

Select item 79211292.

Fibroblast growth factor receptors in cancer: genetic alterations, diagnostics, therapeutic targets and mechanisms of resistance

Melanie A. Krook, Julie W. Reeser, Gabrielle Ernst, Hannah Barker, Max Wilberding, Gary Li, Hui-Zi Chen, Sameek Roychowdhury

Br J Cancer. 2021 Mar 2; 124(5): 880–892. Published online 2020 Dec 3. doi: 10.1038/s41416-020-01157-0

PMCID:: PMC7921129

Abstract Article PDF–1.2M

Select item 73135373.

INCB054828 (pemigatinib), a potent and selective inhibitor of fibroblast growth factor receptors 1, 2, and 3, displays activity against genetically defined tumor models

Phillip C. C. Liu, Holly Koblish, Liangxing Wu, Kevin Bowman, Sharon Diamond, Darlise DiMatteo, Yue Zhang, Michael Hansbury, Mark Rupar, Xiaoming Wen, Paul Collier, Patricia Feldman, Ronald Klabe, Krista A. Burke, Maxim Soloviev, Christine Gardiner, Xin He, Alla Volgina, Maryanne Covington, Bruce Ruggeri, Richard Wynn, Timothy C. Burn, Peggy Scherle, Swamy Yeleswaram, Wenqing Yao, Reid Huber, Gregory Hollis

PLoS One. 2020; 15(4): e0231877. Published online 2020 Apr 21. doi: 10.1371/journal.pone.0231877