PMC Links for Books (Select 4864488) - PMC

Select item 104664571.

Long-Term Outcomes in Patients With BRAF V600–Mutant Metastatic Melanoma Who Received Dabrafenib Combined With Trametinib

Georgina V. Long, Zeynep Eroglu, Jeffrey Infante, Sapna Patel, Adil Daud, Douglas B. Johnson, Rene Gonzalez, Richard Kefford, Omid Hamid, Lynn Schuchter, Jonathan Cebon, William Sharfman, Robert McWilliams, Mario Sznol, Suman Redhu, Eduard Gasal, Bijoyesh Mookerjee, Jeffrey Weber, Keith T. Flaherty

J Clin Oncol. 2018 Mar 1; 36(7): 667–673. Published online 2017 Oct 9. doi: 10.1200/JCO.2017.74.1025

PMCID:: PMC10466457

Abstract Article PDF–789K

Select item 63931182.

Dabrafenib plus trametinib for compassionate use in metastatic melanoma: A STROBE-compliant retrospective observational postauthorization study

Salvador Martín Algarra, Virtudes Soriano, Luis Fernández-Morales, Miguel-Ángel Berciano-Guerrero, Karmele Mujika, José Luis Manzano, Teresa Puértolas Hernández, Ainara Soria, Delvys Rodríguez-Abreu, Enrique Espinosa Arranz, Javier Medina Martínez, Ivan Márquez-Rodas, Jordi Rubió-Casadevall, María Eugenia Ortega, José Miguel Jurado García, María José Lecumberri Biurrun, Isabel Palacio, María Rodríguez de la Borbolla Artacho, Javier Pérez Altozano, Victoria Eugenia Castellón Rubio, Almudena García, Pablo Luna, Anabel Ballesteros, Ovidio Fernández, Jose Antonio López Martín, Alfonso Berrocal, Ana Arance

Medicine (Baltimore) 2017 Dec; 96(52): e9523. Published online 2017 Dec 29. doi: 10.1097/MD.0000000000009523

PMCID:: PMC6393118

Abstract Article PDF–257K

Select item 59916153.

Dabrafenib plus trametinib in patients with BRAF V600–mutant melanoma brain metastases (COMBI-MB): a multi-cohort, open-label, phase 2 trial

Michael A Davies, Prof Philippe Saiag, Prof Caroline Robert, Prof Jean-Jacques Grob, Prof Keith T Flaherty, Ana Arance, Vanna Chiarion-Sileni, Prof Luc Thomas, Thierry Lesimple, Prof Laurent Mortier, Stergios J Moschos, David Hogg, Prof Iván Márquez-Rodas, Prof Michele Del Vecchio, Prof Céleste Lebbé, Prof Nicolas Meyer, Ying Zhang, Yingjie Huang, Bijoyesh Mookerjee, Prof Georgina V Long

Lancet Oncol. Author manuscript; available in PMC 2018 Jul 1.

Published in final edited form as: Lancet Oncol. 2017 Jul; 18(7): 863–873. Published online 2017 Jun 4. doi: 10.1016/S1470-2045(17)30429-1

PMCID:: PMC5991615

Abstract Article PDF–547K

Select item 58341024.

Dabrafenib plus trametinib versus dabrafenib monotherapy in patients with metastatic BRAF V600E/K-mutant melanoma: long-term survival and safety analysis of a phase 3 study

G. V. Long, K. T. Flaherty, D. Stroyakovskiy, H. Gogas, E. Levchenko, F. de Braud, J. Larkin, C. Garbe, T. Jouary, A. Hauschild, V. Chiarion-Sileni, C. Lebbe, M. Mandalà, M. Millward, A. Arance, I. Bondarenko, J. B. A. G. Haanen, J. Hansson, J. Utikal, V. Ferraresi, P. Mohr, V. Probachai, D. Schadendorf, P. Nathan, C. Robert, A. Ribas, M. A. Davies, S. R. Lane, J. J. Legos, B. Mookerjee, J.-J. Grob

Ann Oncol. 2017 Jul; 28(7): 1631–1639. Published online 2017 May 5. doi: 10.1093/annonc/mdx176

Correction in:: Ann Oncol. 2019 Nov; 30(11): 1848.

PMCID:: PMC5834102

Abstract Article PDF–313K

Select item 55200975.

The oral VEGF receptor tyrosine kinase inhibitor pazopanib in combination with the MEK inhibitor trametinib in advanced cholangiocarcinoma

Rachna T Shroff, Mark Yarchoan, Ashley O'Connor, Denise Gallagher, Marianna L Zahurak, Gary Rosner, Chimela Ohaji, Susan Sartorius-Mergenthaler, Vivek Subbiah, Ralph Zinner, Nilofer S Azad

Br J Cancer. 2017 May 23; 116(11): 1402–1407. Published online 2017 Apr 25. doi: 10.1038/bjc.2017.119

Correction in:: Br J Cancer. 2018 Jan; 118(2): e2.

PMCID:: PMC5520097

Abstract Article PDF–312K

Select item 51022466.

Avoiding Severe Toxicity From Combined BRAF Inhibitor and Radiation Treatment: Consensus Guidelines from the Eastern Cooperative Oncology Group (ECOG)

Christopher J. Anker, Kenneth F. Grossmann, Michael B. Atkins, Gita Suneja, Ahmad A. Tarhini, John M. Kirkwood

Int J Radiat Oncol Biol Phys. Author manuscript; available in PMC 2016 Nov 9.

Published in final edited form as: Int J Radiat Oncol Biol Phys. 2016 Jun 1; 95(2): 632–646. doi: 10.1016/j.ijrobp.2016.01.038

Correction in:: Int J Radiat Oncol Biol Phys. 2016 Oct 1; 96(2): 486.

PMCID:: PMC5102246

Abstract Article PDF–667K

Select item 49931037.

An open-label phase 2 trial of dabrafenib plus trametinib in patients with previously treated BRAF V600E–mutant metastatic non-small cell lung cancer

David Planchard, Benjamin Besse, Harry J M Groen, Pierre-Jean Souquet, Elisabeth Quoix, Christina S Baik, Fabrice Barlesi, Tae Min Kim, Julien Mazieres, Silvia Novello, James R Rigas, Allison Upalawanna, Anthony M D’Amelio, Jr, Pingkuan Zhang, Bijoyesh Mookerjee, Bruce E Johnson

Lancet Oncol. Author manuscript; available in PMC 2016 Aug 22.

Published in final edited form as: Lancet Oncol. 2016 Jul; 17(7): 984–993. Published online 2016 Jun 6. doi: 10.1016/S1470-2045(16)30146-2

PMCID:: PMC4993103

Abstract Article PDF–550K

Select item 49764808.

Hepatic Hemorrhage as a Consequence of Rapid Response to Combined Targeted Therapy in Metastatic Melanoma

DEVIN C. FLAHERTY, BRIANNA W. HOFFNER, BRIANA J. LAU, OMID HAMID, MARK B. FARIES

J Surg Oncol. Author manuscript; available in PMC 2016 Dec 1.

Published in final edited form as: J Surg Oncol. 2015 Dec; 112(8): 844–845. Published online 2015 Oct 26. doi: 10.1002/jso.24078

PMCID:: PMC4976480

Abstract Article PDF–170K

Select item 44462359.

Features and Outcomes of 899 Patients with Drug-induced Liver Injury: The DILIN Prospective Study

N Chalasani, HL Bonkovsky, R Fontana, W Lee, A Stolz, J Talwalkar, KR Reddy, PB Watkins, V Navarro, H Barnhart, J Gu, J Serrano, for the United States Drug Induced Liver Injury Network

Gastroenterology. Author manuscript; available in PMC 2016 Jun 1.

Published in final edited form as: Gastroenterology. 2015 Jun; 148(7): 1340–1352.e7. Published online 2015 Mar 6. doi: 10.1053/j.gastro.2015.03.006

PMCID:: PMC4446235

Abstract Article PDF–546K

Select item 422680310.

Combined BRAF (Dabrafenib) and MEK Inhibition (Trametinib) in Patients With BRAF^V600-Mutant Melanoma Experiencing Progression With Single-Agent BRAF Inhibitor

Douglas B. Johnson, Keith T. Flaherty, Jeffrey S. Weber, Jeffrey R. Infante, Kevin B. Kim, Richard F. Kefford, Omid Hamid, Lynn Schuchter, Jonathan Cebon, William H. Sharfman, Robert R. McWilliams, Mario Sznol, Donald P. Lawrence, Geoffrey T. Gibney, Howard A. Burris, III, Gerald S. Falchook, Alain Algazi, Karl Lewis, Georgina V. Long, Kiran Patel, Nageatte Ibrahim, Peng Sun, Shonda Little, Elizabeth Cunningham, Jeffrey A. Sosman, Adil Daud, Rene Gonzalez

J Clin Oncol. 2014 Nov 20; 32(33): 3697–3704. Published online 2014 Oct 6. doi: 10.1200/JCO.2014.57.3535

PMCID:: PMC4226803

Abstract Article PDF–354K

Select item 410928811.

RAF Inhibitor Dabrafenib (GSK2118436) is Active in Melanoma Brain Metastases, Multiple BRAF Genotypes and Diverse Cancers

G.S. Falchook, G.V. Long, R. Kurzrock, K.B. Kim, H.T. Arkenau, M.P. Brown, O. Hamid, J.R. Infante, M. Millward, A. Pavlick, S.J. O’Day, S.C. Blackman, C.M. Curtis, P. Lebowitz, B. Ma, D. Ouellet, R.F. Kefford

Lancet. Author manuscript; available in PMC 2014 Jul 24.

Published in final edited form as: Lancet. 2012 May 19; 379(9829): 1893–1901. doi: 10.1016/S0140-6736(12)60398-5

PMCID:: PMC4109288

Abstract Article PDF–1.1M

Select item 370107012.

Dabrafenib; Preclinical Characterization, Increased Efficacy when Combined with Trametinib, while BRAF/MEK Tool Combination Reduced Skin Lesions

Alastair J. King, Marc R. Arnone, Maureen R. Bleam, Katherine G. Moss, Jingsong Yang, Kelly E. Fedorowicz, Kimberly N. Smitheman, Joseph A. Erhardt, Angela Hughes-Earle, Laurie S. Kane-Carson, Robert H. Sinnamon, Hongwei Qi, Tara R. Rheault, David E. Uehling, Sylvie G. Laquerre

PLoS One. 2013; 8(7): e67583. Published online 2013 Jul 3. doi: 10.1371/journal.pone.0067583

PMCID:: PMC3701070

Abstract Article PDF–1.5M

Select item 354929513.

Combined BRAF and MEK Inhibition in Melanoma with BRAF V600 Mutations

Keith T. Flaherty, Jeffery R. Infante, Adil Daud, Rene Gonzalez, Richard F. Kefford, Jeffrey Sosman, Omid Hamid, Lynn Schuchter, Jonathan Cebon, Nageatte Ibrahim, Ragini Kudchadkar, Howard A. Burris, III, Gerald Falchook, Alain Algazi, Karl Lewis, Georgina V. Long, Igor Puzanov, Peter Lebowitz, Ajay Singh, Shonda Little, Peng Sun, Alicia Allred, Daniele Ouellet, Kevin B. Kim, Kiran Patel, Jeffrey Weber

N Engl J Med. Author manuscript; available in PMC 2013 Jan 19.

Published in final edited form as: N Engl J Med. 2012 Nov; 367(18): 1694–1703. Published online 2012 Sep 29. doi: 10.1056/NEJMoa1210093

PMCID:: PMC3549295

Abstract Article PDF–434K

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