PMC Links for Books (Select 4854322) - PMC

Select item 74518101.

Characterisation of liver chemistry abnormalities associated with pazopanib monotherapy: A systematic review and meta-analysis of clinical trials in advanced cancer patients

Thomas Powles, Sergio Bracarda, Mei Chen, Elliot Norry, Natalie Compton, Mark Heise, Thomas Hutson, Philipp Harter, Christopher Carpenter, Lini Pandite, Neil Kaplowitz

Eur J Cancer. Author manuscript; available in PMC 2020 Aug 27.

Published in final edited form as: Eur J Cancer. 2015 Jul; 51(10): 1293–1302. Published online 2015 Apr 17. doi: 10.1016/j.ejca.2015.03.019

PMCID:: PMC7451810

Abstract Article PDF–468K

Select item 74449942.

HLA-B*57:01 Confers Susceptibility to Pazopanib-Associated Liver Injury in Patients with Cancer

Chun-Fang Xu, Toby Johnson, Xiaojing Wang, Chris Carpenter, Alan P. Graves, Liling Warren, Zhengyu Xue, Karen S. King, Dana J. Fraser, Sandy Stinnett, Linda P. Briley, Ionel Mitrica, Colin F. Spraggs, Matthew R. Nelson, Hiroomi Tada, Andreas du Bois, Thomas Powles, Neil Kaplowitz, Lini N. Pandite

Clin Cancer Res. Author manuscript; available in PMC 2020 Aug 24.

Published in final edited form as: Clin Cancer Res. 2016 Mar 15; 22(6): 1371–1377. Published online 2015 Nov 6. doi: 10.1158/1078-0432.CCR-15-2044

PMCID:: PMC7444994

Abstract Article PDF–593K

Select item 69353423.

Novel Use of N-Acetylcysteine in Management of Tyrosine Kinase Inhibitor Induced Acute Liver Injury

Tarang Patel, Tushar Tarun, Dania Hudhud, Armin Krvavac

Cureus. 2019 Nov; 11(11): e6251. Published online 2019 Nov 27. doi: 10.7759/cureus.6251

PMCID:: PMC6935342

Abstract Article PDF–534K

Select item 63941104.

Hyperbilirubinemia in pazopanib- or sunitinib-treated patients in COMPARZ is associated with UGT1A1 polymorphisms

R. J. Motzer, T. Johnson, T. K. Choueiri, K. C. Deen, Z. Xue, L. N. Pandite, C. Carpenter, C. F. Xu

Ann Oncol. 2013 Nov; 24(11): 2927–2928. Published online 2013 Oct 9. doi: 10.1093/annonc/mdt394

PMCID:: PMC6394110

Article PDF–168K

Select item 57786985.

A remarkable response to pazopanib, despite recurrent liver toxicity, in a patient with a high grade endometrial stromal sarcoma, a case report

Arie J. Verschoor, Fabiënne A. R. M. Warmerdam, Tjalling Bosse, Judith V. M. G. Bovée, Hans Gelderblom

BMC Cancer. 2018; 18: 92. Published online 2018 Jan 22. doi: 10.1186/s12885-018-3999-0

PMCID:: PMC5778698

Abstract Article PDF–2.0M

Select item 50106036.

Occurrence of hepatotoxicity with pazopanib and other anti-VEGF treatments for renal cell carcinoma: an observational study utilizing a distributed database network

Sumitra Shantakumar, Beth L. Nordstrom, Luc Djousse, Susan A. Hall, David R. Gagnon, Kathy H. Fraeman, Myrthe van Herk-Sukel, Karen Chagin, Jeanenne Nelson

Cancer Chemother Pharmacol. 2016; 78(3): 559–566. Published online 2016 Jul 20. doi: 10.1007/s00280-016-3112-9

PMCID:: PMC5010603

Abstract Article PDF–411K

Select item 44444397.

Hepatotoxicity of molecular targeted therapy

Bożenna Karczmarek-Borowska, Agata Sałek-Zań

Contemp Oncol (Pozn) 2015; 19(2): 87–92. Published online 2014 Aug 29. doi: 10.5114/wo.2014.43495

PMCID:: PMC4444439

Abstract Article PDF–72K

Select item 40107058.

A Multicenter Phase 2 Trial of Pazopanib in Metastatic and Progressive Medullary Thyroid Carcinoma: MC057H

Keith C. Bible, Vera J. Suman, Julian R. Molina, Robert C. Smallridge, William J. Maples, Michael E. Menefee, Joseph Rubin, Nina Karlin, Kostandinos Sideras, John C. Morris, III, Bryan McIver, Ian Hay, Vahab Fatourechi, Jill K. Burton, Kevin P. Webster, Carolyn Bieber, Anne M. Traynor, Patrick J. Flynn, Boon Cher Goh, Crescent R. Isham, Pamela Harris, Charles Erlichman

J Clin Endocrinol Metab. 2014 May; 99(5): 1687–1693. Published online 2014 Feb 25. doi: 10.1210/jc.2013-3713

PMCID:: PMC4010705

Abstract Article

Select item 37006239.

Phase 1 Study of Pazopanib in Patients with Advanced Solid Tumors and Hepatic Dysfunction: A National Cancer Institute Organ Dysfunction Working Group Study

Stephen I Shibata, Vincent Chung, Timothy Synold, Jeffrey Longmate, A Benjamin Suttle, Lone H Ottesen, Heinz-Josef Lenz, Shivaani Kummar, R Donald Harvey, Anne Hamilton, Bert O’Neil, John Sarantopoulos, Patricia LoRusso, Michelle A Rudek, Afshin Dowlati, Daniel Mulkerin, Chandra P. Belani, Leena Gandhi, Cecilia Lau, S. Percy Ivy, Edward M. Newman

Clin Cancer Res. Author manuscript; available in PMC 2014 Jul 1.

Published in final edited form as: Clin Cancer Res. 2013 Jul 1; 19(13): 3631–3639. Published online 2013 May 7. doi: 10.1158/1078-0432.CCR-12-3214

PMCID:: PMC3700623

Abstract Article PDF–713K

Select item 286576110.

Pazopanib-induced hyperbilirubinemia is associated with Gilbert's syndrome UGT1A1 polymorphism

C-F Xu, B H Reck, Z Xue, L Huang, K L Baker, M Chen, E P Chen, H E Ellens, V E Mooser, L R Cardon, C F Spraggs, L Pandite

Br J Cancer. 2010 Apr 27; 102(9): 1371–1377. Published online 2010 Apr 13. doi: 10.1038/sj.bjc.6605653

PMCID:: PMC2865761

Abstract Article PDF–431K

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