8RHL: Yeast 20S proteasome in complex with a linear biarylether epoxyketone (compound 15a)

PDB ID: 8RHLDownload
MMDB ID: 246137
PDB Deposition Date: 2023/12/15
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 3.2  Å
Source Organism:
Similar Structures:
Biological Unit for 8RHL: 32-meric; determined by author
Molecular Components in 8RHL
Label Count Molecule
Proteins (28 molecules)
2
Proteasome Subunit Alpha Type-2
Molecule annotation
2
Proteasome Subunit Alpha Type-3
Molecule annotation
2
Proteasome Subunit Alpha Type-4
Molecule annotation
2
Proteasome Subunit Alpha Type-5
Molecule annotation
2
Proteasome Subunit Alpha Type-6
Molecule annotation
2
Probable Proteasome Subunit Alpha Type-7
Molecule annotation
2
Proteasome Subunit Alpha Type-1
Molecule annotation
2
Proteasome Subunit Beta Type-2
Molecule annotation
2
Proteasome Subunit Beta Type-3
Molecule annotation
2
Proteasome Subunit Beta Type-4
Molecule annotation
2
Proteasome Subunit Beta Type-5
Molecule annotation
2
Proteasome Subunit Beta Type-6
Molecule annotation
2
Proteasome Subunit Beta Type-7
Molecule annotation
2
Proteasome Subunit Beta Type-1
Molecule annotation
Chemicals and Non-standard biopolymers (15 molecules)
efgh
4
Linear biarylether epoxyketone
1
8
MAGNESIUM IONMAGNESIUM ION
2
2
CHLORIDE IONCHLORIDE ION
3
1
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303