NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|50812102|ref|YP_054501|]
View 

COX1 intron 3 ORF (mitochondrion) [Kluyveromyces lactis]

Protein Classification

LAGLIDADG family homing endonuclease( domain architecture ID 10469810)

LAGLIDADG family homing endonuclease belongs to a large family of homing endonucleases that each contain one or two copies of a motif that resembles the consensus sequence LAGLIDADG and is directly involved in the DNA cutting process

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
LAGLIDADG_1 pfam00961
LAGLIDADG endonuclease;
308-394 1.91e-04

LAGLIDADG endonuclease;


:

Pssm-ID: 395767  Cd Length: 101  Bit Score: 40.31  E-value: 1.91e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50812102   308 FLGFIENKGKFIIRKNNNNSFLFYIN-----------DKHLIEFLKNYFNIKNKLIYKNNI-YILEVYNKYYI-NIFIKF 374
Cdd:pfam00961   1 LAGFIDGDGSFSINVTKSKSYKGYRVrlrfqislhskDENLLEKIKNYLGIGSISKRKNDNtVIYIISNSKKSlNIIIPY 80

                          90       100
                  ....*....|....*....|
gi 50812102   375 FNKYNLQGYKYIEYIKWKKI 394
Cdd:pfam00961  81 FDKYPLLTSKYLDYLDFKKI 100
LAGLIDADG_1 pfam00961
LAGLIDADG endonuclease;
142-233 6.04e-04

LAGLIDADG endonuclease;


:

Pssm-ID: 395767  Cd Length: 101  Bit Score: 38.77  E-value: 6.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50812102   142 FVGLFDSNGNIQINKYKSKYL---QFRLIIKLNNNKENINILNNIKHYLKGNININNNYVIWIINDIKNINNLIKL---- 214
Cdd:pfam00961   1 LAGFIDGDGSFSINVTKSKSYkgyRVRLRFQISLHSKDENLLEKIKNYLGIGSISKRKNDNTVIYIISNSKKSLNIiipy 80

                          90
                  ....*....|....*....
gi 50812102   215 FNKYPLITINKKLQLAFIK 233
Cdd:pfam00961  81 FDKYPLLTSKYLDYLDFKK 99
 
Name Accession Description Interval E-value
LAGLIDADG_1 pfam00961
LAGLIDADG endonuclease;
308-394 1.91e-04

LAGLIDADG endonuclease;


Pssm-ID: 395767  Cd Length: 101  Bit Score: 40.31  E-value: 1.91e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50812102   308 FLGFIENKGKFIIRKNNNNSFLFYIN-----------DKHLIEFLKNYFNIKNKLIYKNNI-YILEVYNKYYI-NIFIKF 374
Cdd:pfam00961   1 LAGFIDGDGSFSINVTKSKSYKGYRVrlrfqislhskDENLLEKIKNYLGIGSISKRKNDNtVIYIISNSKKSlNIIIPY 80

                          90       100
                  ....*....|....*....|
gi 50812102   375 FNKYNLQGYKYIEYIKWKKI 394
Cdd:pfam00961  81 FDKYPLLTSKYLDYLDFKKI 100
LAGLIDADG_1 pfam00961
LAGLIDADG endonuclease;
142-233 6.04e-04

LAGLIDADG endonuclease;


Pssm-ID: 395767  Cd Length: 101  Bit Score: 38.77  E-value: 6.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50812102   142 FVGLFDSNGNIQINKYKSKYL---QFRLIIKLNNNKENINILNNIKHYLKGNININNNYVIWIINDIKNINNLIKL---- 214
Cdd:pfam00961   1 LAGFIDGDGSFSINVTKSKSYkgyRVRLRFQISLHSKDENLLEKIKNYLGIGSISKRKNDNTVIYIISNSKKSLNIiipy 80

                          90
                  ....*....|....*....
gi 50812102   215 FNKYPLITINKKLQLAFIK 233
Cdd:pfam00961  81 FDKYPLLTSKYLDYLDFKK 99
 
Name Accession Description Interval E-value
LAGLIDADG_1 pfam00961
LAGLIDADG endonuclease;
308-394 1.91e-04

LAGLIDADG endonuclease;


Pssm-ID: 395767  Cd Length: 101  Bit Score: 40.31  E-value: 1.91e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50812102   308 FLGFIENKGKFIIRKNNNNSFLFYIN-----------DKHLIEFLKNYFNIKNKLIYKNNI-YILEVYNKYYI-NIFIKF 374
Cdd:pfam00961   1 LAGFIDGDGSFSINVTKSKSYKGYRVrlrfqislhskDENLLEKIKNYLGIGSISKRKNDNtVIYIISNSKKSlNIIIPY 80

                          90       100
                  ....*....|....*....|
gi 50812102   375 FNKYNLQGYKYIEYIKWKKI 394
Cdd:pfam00961  81 FDKYPLLTSKYLDYLDFKKI 100
LAGLIDADG_1 pfam00961
LAGLIDADG endonuclease;
142-233 6.04e-04

LAGLIDADG endonuclease;


Pssm-ID: 395767  Cd Length: 101  Bit Score: 38.77  E-value: 6.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 50812102   142 FVGLFDSNGNIQINKYKSKYL---QFRLIIKLNNNKENINILNNIKHYLKGNININNNYVIWIINDIKNINNLIKL---- 214
Cdd:pfam00961   1 LAGFIDGDGSFSINVTKSKSYkgyRVRLRFQISLHSKDENLLEKIKNYLGIGSISKRKNDNTVIYIISNSKKSLNIiipy 80

                          90
                  ....*....|....*....
gi 50812102   215 FNKYPLITINKKLQLAFIK 233
Cdd:pfam00961  81 FDKYPLLTSKYLDYLDFKK 99
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH