NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1320058681|gb|PLN00049|]
View 

aquaporin Z [Klebsiella quasipneumoniae]

Protein Classification

aquaporin Z( domain architecture ID 10012387)

aquaporin Z is involved in osmoregulation, allowing water to move into and out of the cell in response to osmotic pressure

CATH:  1.20.1080.10
Gene Ontology:  GO:0055085|GO:0015250|GO:0006833
PubMed:  11964478|11473620|8849412
SCOP:  3000508
TCDB:  1.A.8

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PRK05420 PRK05420
aquaporin Z; Provisional
 1-231 9.67e-146

aquaporin Z; Provisional


:

Pssm-ID: 235453 [Multi-domain]  Cd Length: 231  Bit Score: 405.89  E-value: 9.67e-146
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681   1 MFRKLAAECFGTFWLVFGGCGSAVLAAAFPELGIGFAGVALAFGLTVLTMAYAVGHISGGHFNPAVTLGLWAGGRFPAKE 80
Cdd:PRK05420    1 MFKKLAAEFFGTFWLVFGGCGSAVLAAAFPELGIGFLGVALAFGLTVLTMAYAVGHISGGHFNPAVSVGLWAGGRFPAKE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681  81 VIGYIIAQVVGGIIAAAVLYVVASGKAGFDAAASGFASNGYGEHSPGGFSMLSAIVIEIVLTCGFLLVIHGATDKHAPAG 160
Cdd:PRK05420   81 LVPYIIAQVVGGIAAAAVLYLIASGKAGFDLAGSGFASNGYGEHSPGGYSLLAALVCEVVLTAFFLLVILGATDKRAPAG 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1320058681 161 FAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALQQLWLFWVMPIVGGILGGVLYRTLLEKRD 231
Cdd:PRK05420  161 FAPIAIGLALTLIHLISIPVTNTSVNPARSTGVALFVGGWALEQLWLFWVAPIVGAIIGGLIYRLLLEKDD 231
 
Name Accession Description Interval E-value
PRK05420 PRK05420
aquaporin Z; Provisional
 1-231 9.67e-146

aquaporin Z; Provisional


Pssm-ID: 235453 [Multi-domain]  Cd Length: 231  Bit Score: 405.89  E-value: 9.67e-146
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681   1 MFRKLAAECFGTFWLVFGGCGSAVLAAAFPELGIGFAGVALAFGLTVLTMAYAVGHISGGHFNPAVTLGLWAGGRFPAKE 80
Cdd:PRK05420    1 MFKKLAAEFFGTFWLVFGGCGSAVLAAAFPELGIGFLGVALAFGLTVLTMAYAVGHISGGHFNPAVSVGLWAGGRFPAKE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681  81 VIGYIIAQVVGGIIAAAVLYVVASGKAGFDAAASGFASNGYGEHSPGGFSMLSAIVIEIVLTCGFLLVIHGATDKHAPAG 160
Cdd:PRK05420   81 LVPYIIAQVVGGIAAAAVLYLIASGKAGFDLAGSGFASNGYGEHSPGGYSLLAALVCEVVLTAFFLLVILGATDKRAPAG 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1320058681 161 FAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALQQLWLFWVMPIVGGILGGVLYRTLLEKRD 231
Cdd:PRK05420  161 FAPIAIGLALTLIHLISIPVTNTSVNPARSTGVALFVGGWALEQLWLFWVAPIVGAIIGGLIYRLLLEKDD 231
GlpF COG0580
Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) ...
 1-228 1.22e-76

Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) [Carbohydrate transport and metabolism];


Pssm-ID: 440345 [Multi-domain]  Cd Length: 232  Bit Score: 230.78  E-value: 1.22e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681   1 MFRKLAAECFGTFWLVFGGCGS-AVLAAAFPelGIGFAGVALAFGLTVLTMAYAVGHISGGHFNPAVTLGLWAGGRFPAK 79
Cdd:COG0580     2 LMKRLLAEFLGTFILVLLGCGVvAVLAGTKG--GIGWLGIALAWGLAVLAGVYAFGHISGAHLNPAVTLALAVAGRFPWK 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681  80 EVIGYIIAQVVGGIIAAAVLYVVASGKagFDAAASGFASNGYGEHSPG-GFSMLSAIVIEIVLTCGFLLVIHGATDKH-A 157
Cdd:COG0580    80 DVLPYIIAQLLGAFLGAALVYLIYGGH--FDATEDGGAKLGVFATSPAiGYSLGAAFLTEIIGTFVLVFVILGITDKRaA 157

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1320058681 158 PAGFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQ----GGWALQQLWLFWVMPIVGGILGGVLYRTLLE 228
Cdd:COG0580   158 PGGLAPLAIGLLVAAIGLSLGPLTGYAINPARDLGPRLFHalgkGGSDWGYLWVPIVAPILGAALAALLYRALFG 232
MIP cd00333
Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane ...
 3-226 4.83e-66

Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal cytosolic portion followed by six transmembrane helices, which might have arisen through gene duplication. On the basis of sequence similarity and functional characteristics, the superfamily can be subdivided into two major groups: water-selective channels called aquaporins (AQPs) and glycerol uptake facilitators (GlpFs). AQPs are found in all three kingdoms of life, while GlpFs have been characterized only within microorganisms.


Pssm-ID: 238204  Cd Length: 228  Bit Score: 203.64  E-value: 4.83e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681   3 RKLAAECFGTFWLVFGGCGSAVLAAAFPELGIGFAGVALAFGLTVLTMAYAVGHISGGHFNPAVTLGLWAGGRFPAKEVI 82
Cdd:cd00333     1 RKYLAEFLGTFLLVFFGCGSVLAVKLAGGASGGLLGIALAWGFAIFVLVYAVGHISGGHINPAVTLALAVGGRFPLIRVI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681  83 GYIIAQVVGGIIAAAVLYVVASGKAGFDAAASGFASNGYGEHSPGGFSMLSAIVIEIVLTCGFLLVIHGATDK---HAPA 159
Cdd:cd00333    81 PYIIAQLLGAILGAALLYGLYYGLYLEFLGANNIVAGIFGTYPSPGVSNGNAFFVEFIGTFILVLVVFATTDDpngPPPG 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1320058681 160 GFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGW-ALQQLWLFWVMPIVGGILGGVLYRTL 226
Cdd:cd00333   161 GLAPLAIGLLVAAIGLAGGPITGASMNPARSLGPALFTGLArHWHYFWVYWVGPLIGAIAGALVYDYV 228
MIP TIGR00861
MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is ...
 7-223 3.88e-63

MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is large and diverse, possessing over 100 members that all form transmembrane channels. These channel proteins function in water, smallcarbohydrate (e.g., glycerol), urea, NH3, CO2 and possibly ion transport by an energy independent mechanism. They are found ubiquitously in bacteria, archaeaand eukaryotes. The MIP family contains two major groups of channels: aquaporins and glycerol facilitators.The known aquaporins cluster loosely together as do the known glycerol facilitators. MIP family proteins are believed to form aqueous pores that selectively allow passive transport of their solute(s) across the membrane with minimal apparent recognition. Aquaporins selectively transport water (but not glycerol) while glycerol facilitators selectively transport glycerol but not water. Some aquaporins can transport NH3 and CO2. Glycerol facilitators function as solute nonspecific channels, and may transport glycerol, dihydroxyacetone, propanediol, urea and other small neutral molecules in physiologically importantprocesses. Some members of the family, including the yeast FPS protein (TC #1.A.8.5.1) and tobacco NtTIPA may transport both water and small solutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273306 [Multi-domain]  Cd Length: 216  Bit Score: 195.98  E-value: 3.88e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681   7 AECFGTFWLVFGGCGSAV---LAAAFPELGIG-FAGVALAFGLTVLTMAYAVGHISGGHFNPAVTLGLWAGGRFPAKEVI 82
Cdd:TIGR00861   1 AEFLGTFLLVFFGVGSALgvnVAGAYGAVGGGqFLGVALAFGLAVATLVYCVGGISGAHLNPAVTIALLLGRRFPLKRVP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681  83 GYIIAQVVGGIIAAAVLYVVASGKAGFDAAASGFASNGYgehspggfSMLSAIVIEIVLTCGFLLVIHGATDK---HAPA 159
Cdd:TIGR00861  81 VYIVAQLIGAILGAALLYGLTSGLFPGNLAVNGSASAGV--------SSGQAFFVEFIGTAILVLVIFATTDDrnrVPRG 152

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1320058681 160 GFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALQQLWLFWVMPIVGGILGGVLY 223
Cdd:TIGR00861 153 GFAPLAIGLLVFLIHLSMGPYTGTGMNPARSLGPALFAGLAGWGNHWVYWVGPIIGAILGALVY 216
MIP pfam00230
Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two ...
 3-223 1.30e-45

Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two distinct types of channel properties: (1) specific water transport by the aquaporins, and (2) small neutral solutes transport, such as glycerol by the glycerol facilitators.


Pssm-ID: 395174 [Multi-domain]  Cd Length: 223  Bit Score: 151.32  E-value: 1.30e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681   3 RKLAAECFGTFWLVFGGCGSAV-LAAAFPELG-IGFAGVALAFGLTVLTMAYAVGHISGGHFNPAVTLGLWAGGRFPAKE 80
Cdd:pfam00230   9 RAVIAEFLATLLFVFFGVGSALgVKKLVSSLAvSGLLAVALAFGLALATLVYCAGHISGAHLNPAVTLALLVGRRFSLLR 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681  81 VIGYIIAQVVGGIIAAAVLYVVASGKAGFDAAASGFASngygehspgGFSMLSAIVIEIVLTCGFLLVIHGATD--KHAP 158
Cdd:pfam00230  89 AIFYIVAQLLGAIAGAALLYGVTVGLQRAGLFANTLAP---------GVNAGQAFVVEIILTFQLVYCVFATTDdrRNGS 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1320058681 159 AGF-APIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWalQQLWLFWVMPIVGGILGGVLY 223
Cdd:pfam00230 160 LGTvAPLAIGFAVFLNHLAGGPYTGASMNPARSFGPAVVLWKW--DDHWVYWVGPFIGAALGALVY 223
 
Name Accession Description Interval E-value
PRK05420 PRK05420
aquaporin Z; Provisional
 1-231 9.67e-146

aquaporin Z; Provisional


Pssm-ID: 235453 [Multi-domain]  Cd Length: 231  Bit Score: 405.89  E-value: 9.67e-146
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681   1 MFRKLAAECFGTFWLVFGGCGSAVLAAAFPELGIGFAGVALAFGLTVLTMAYAVGHISGGHFNPAVTLGLWAGGRFPAKE 80
Cdd:PRK05420    1 MFKKLAAEFFGTFWLVFGGCGSAVLAAAFPELGIGFLGVALAFGLTVLTMAYAVGHISGGHFNPAVSVGLWAGGRFPAKE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681  81 VIGYIIAQVVGGIIAAAVLYVVASGKAGFDAAASGFASNGYGEHSPGGFSMLSAIVIEIVLTCGFLLVIHGATDKHAPAG 160
Cdd:PRK05420   81 LVPYIIAQVVGGIAAAAVLYLIASGKAGFDLAGSGFASNGYGEHSPGGYSLLAALVCEVVLTAFFLLVILGATDKRAPAG 160

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1320058681 161 FAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALQQLWLFWVMPIVGGILGGVLYRTLLEKRD 231
Cdd:PRK05420  161 FAPIAIGLALTLIHLISIPVTNTSVNPARSTGVALFVGGWALEQLWLFWVAPIVGAIIGGLIYRLLLEKDD 231
GlpF COG0580
Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) ...
 1-228 1.22e-76

Glycerol uptake facilitator or related aquaporin (Major Intrinsic protein Family) [Carbohydrate transport and metabolism];


Pssm-ID: 440345 [Multi-domain]  Cd Length: 232  Bit Score: 230.78  E-value: 1.22e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681   1 MFRKLAAECFGTFWLVFGGCGS-AVLAAAFPelGIGFAGVALAFGLTVLTMAYAVGHISGGHFNPAVTLGLWAGGRFPAK 79
Cdd:COG0580     2 LMKRLLAEFLGTFILVLLGCGVvAVLAGTKG--GIGWLGIALAWGLAVLAGVYAFGHISGAHLNPAVTLALAVAGRFPWK 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681  80 EVIGYIIAQVVGGIIAAAVLYVVASGKagFDAAASGFASNGYGEHSPG-GFSMLSAIVIEIVLTCGFLLVIHGATDKH-A 157
Cdd:COG0580    80 DVLPYIIAQLLGAFLGAALVYLIYGGH--FDATEDGGAKLGVFATSPAiGYSLGAAFLTEIIGTFVLVFVILGITDKRaA 157

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1320058681 158 PAGFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQ----GGWALQQLWLFWVMPIVGGILGGVLYRTLLE 228
Cdd:COG0580   158 PGGLAPLAIGLLVAAIGLSLGPLTGYAINPARDLGPRLFHalgkGGSDWGYLWVPIVAPILGAALAALLYRALFG 232
MIP cd00333
Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane ...
 3-226 4.83e-66

Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal cytosolic portion followed by six transmembrane helices, which might have arisen through gene duplication. On the basis of sequence similarity and functional characteristics, the superfamily can be subdivided into two major groups: water-selective channels called aquaporins (AQPs) and glycerol uptake facilitators (GlpFs). AQPs are found in all three kingdoms of life, while GlpFs have been characterized only within microorganisms.


Pssm-ID: 238204  Cd Length: 228  Bit Score: 203.64  E-value: 4.83e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681   3 RKLAAECFGTFWLVFGGCGSAVLAAAFPELGIGFAGVALAFGLTVLTMAYAVGHISGGHFNPAVTLGLWAGGRFPAKEVI 82
Cdd:cd00333     1 RKYLAEFLGTFLLVFFGCGSVLAVKLAGGASGGLLGIALAWGFAIFVLVYAVGHISGGHINPAVTLALAVGGRFPLIRVI 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681  83 GYIIAQVVGGIIAAAVLYVVASGKAGFDAAASGFASNGYGEHSPGGFSMLSAIVIEIVLTCGFLLVIHGATDK---HAPA 159
Cdd:cd00333    81 PYIIAQLLGAILGAALLYGLYYGLYLEFLGANNIVAGIFGTYPSPGVSNGNAFFVEFIGTFILVLVVFATTDDpngPPPG 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1320058681 160 GFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGW-ALQQLWLFWVMPIVGGILGGVLYRTL 226
Cdd:cd00333   161 GLAPLAIGLLVAAIGLAGGPITGASMNPARSLGPALFTGLArHWHYFWVYWVGPLIGAIAGALVYDYV 228
MIP TIGR00861
MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is ...
 7-223 3.88e-63

MIP family channel proteins; 1.A.8 The Major Intrinsic Protein (MIP) FamilyThe MIP family is large and diverse, possessing over 100 members that all form transmembrane channels. These channel proteins function in water, smallcarbohydrate (e.g., glycerol), urea, NH3, CO2 and possibly ion transport by an energy independent mechanism. They are found ubiquitously in bacteria, archaeaand eukaryotes. The MIP family contains two major groups of channels: aquaporins and glycerol facilitators.The known aquaporins cluster loosely together as do the known glycerol facilitators. MIP family proteins are believed to form aqueous pores that selectively allow passive transport of their solute(s) across the membrane with minimal apparent recognition. Aquaporins selectively transport water (but not glycerol) while glycerol facilitators selectively transport glycerol but not water. Some aquaporins can transport NH3 and CO2. Glycerol facilitators function as solute nonspecific channels, and may transport glycerol, dihydroxyacetone, propanediol, urea and other small neutral molecules in physiologically importantprocesses. Some members of the family, including the yeast FPS protein (TC #1.A.8.5.1) and tobacco NtTIPA may transport both water and small solutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273306 [Multi-domain]  Cd Length: 216  Bit Score: 195.98  E-value: 3.88e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681   7 AECFGTFWLVFGGCGSAV---LAAAFPELGIG-FAGVALAFGLTVLTMAYAVGHISGGHFNPAVTLGLWAGGRFPAKEVI 82
Cdd:TIGR00861   1 AEFLGTFLLVFFGVGSALgvnVAGAYGAVGGGqFLGVALAFGLAVATLVYCVGGISGAHLNPAVTIALLLGRRFPLKRVP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681  83 GYIIAQVVGGIIAAAVLYVVASGKAGFDAAASGFASNGYgehspggfSMLSAIVIEIVLTCGFLLVIHGATDK---HAPA 159
Cdd:TIGR00861  81 VYIVAQLIGAILGAALLYGLTSGLFPGNLAVNGSASAGV--------SSGQAFFVEFIGTAILVLVIFATTDDrnrVPRG 152

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1320058681 160 GFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALQQLWLFWVMPIVGGILGGVLY 223
Cdd:TIGR00861 153 GFAPLAIGLLVFLIHLSMGPYTGTGMNPARSLGPALFAGLAGWGNHWVYWVGPIIGAILGALVY 216
MIP pfam00230
Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two ...
 3-223 1.30e-45

Major intrinsic protein; MIP (Major Intrinsic Protein) family proteins exhibit essentially two distinct types of channel properties: (1) specific water transport by the aquaporins, and (2) small neutral solutes transport, such as glycerol by the glycerol facilitators.


Pssm-ID: 395174 [Multi-domain]  Cd Length: 223  Bit Score: 151.32  E-value: 1.30e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681   3 RKLAAECFGTFWLVFGGCGSAV-LAAAFPELG-IGFAGVALAFGLTVLTMAYAVGHISGGHFNPAVTLGLWAGGRFPAKE 80
Cdd:pfam00230   9 RAVIAEFLATLLFVFFGVGSALgVKKLVSSLAvSGLLAVALAFGLALATLVYCAGHISGAHLNPAVTLALLVGRRFSLLR 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681  81 VIGYIIAQVVGGIIAAAVLYVVASGKAGFDAAASGFASngygehspgGFSMLSAIVIEIVLTCGFLLVIHGATD--KHAP 158
Cdd:pfam00230  89 AIFYIVAQLLGAIAGAALLYGVTVGLQRAGLFANTLAP---------GVNAGQAFVVEIILTFQLVYCVFATTDdrRNGS 159

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1320058681 159 AGF-APIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWalQQLWLFWVMPIVGGILGGVLY 223
Cdd:pfam00230 160 LGTvAPLAIGFAVFLNHLAGGPYTGASMNPARSFGPAVVLWKW--DDHWVYWVGPFIGAALGALVY 223
PLN00184 PLN00184
aquaporin NIP1; Provisional
 2-226 9.15e-40

aquaporin NIP1; Provisional


Pssm-ID: 177778  Cd Length: 296  Bit Score: 138.62  E-value: 9.15e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681   2 FRKLAAECFGTFWLVFGGCGSAVLAAAFPELgIGFAGVALAFGLTVLTMAYAVGHISGGHFNPAVTLGLWAGGRFPAKEV 81
Cdd:PLN00184   54 LQKLIAEVLGTYFLVFTGCASVVVNMQNDNV-VTLPGIAIVWGLTIMVLIYSLGHISGAHINPAVTIAFASCGRFPLKQV 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681  82 IGYIIAQVVGGIIAAAVLYVVasgkAGFDAAASGFASNGYGEHSPGGfSMLSAIVIEIVLTCGFLLVIHG-ATDKHAPAG 160
Cdd:PLN00184  133 PAYVISQVIGSTLAAATLRLL----FGLDHDVCSGKHDVFIGSSPVG-SDLQAFVMEFIVTFYLMFIISGvATDNRAIGE 207

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1320058681 161 FAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWalQQLWLFWVMPIVGGILGGVLYRTL 226
Cdd:PLN00184  208 LAGLAIGSTVLLNVLIAAPVSSASMNPGRSLGPAMVYGCY--KGIWIYIVAPTLGAIAGAWVYNTV 271
PLN00182 PLN00182
putative aquaporin NIP4; Provisional
 3-223 8.87e-33

putative aquaporin NIP4; Provisional


Pssm-ID: 165748  Cd Length: 283  Bit Score: 120.01  E-value: 8.87e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681   3 RKLAAECFGTFWLVFGGCGSAVLAAAFPElGIGFAGVALAFGLTVLTMAYAVGHISGGHFNPAVTLGLWAGGRFPAKEVI 82
Cdd:PLN00182   43 QKLIAEMIGTYFIIFSGCGVVVVNVLYGG-TITFPGICVTWGLIVMVMIYSTGHISGAHFNPAVTVTFAIFRRFPWYQVP 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681  83 GYIIAQVVGGIIAAAVLYVVasgkagFDAAASGFASNgygehSPGGfSMLSAIVIEIVLTCGFLLVIHG-ATDKHAPAGF 161
Cdd:PLN00182  122 LYIGAQLTGSLLASLTLRLM------FNVTPEAFFGT-----TPTD-SSGQALVAEIIISFLLMFVISGvATDSRAVGEL 189

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1320058681 162 APIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWalQQLWLFWVMPIVGGILGGVLY 223
Cdd:PLN00182  190 AGIAVGMTIILNVFVAGPISGASMNPARSLGPAIVMGRY--KGIWVYIVGPFVGIIAGGFVY 249
PTZ00016 PTZ00016
aquaglyceroporin; Provisional
 1-227 4.85e-25

aquaglyceroporin; Provisional


Pssm-ID: 240230 [Multi-domain]  Cd Length: 294  Bit Score: 99.81  E-value: 4.85e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681   1 MFRKLAAECFGTFWLVFGGCGsAVLAAAFPELGIGFAGVALAFGLTVLTMAYAVGHISGGHFNPAVTLGLWAGGRFPAKE 80
Cdd:PTZ00016   49 NVREYVAEFLGTFVLLFFGEG-VVATTHTVGNNGDYLAITIGWGLGVTFGLLVSAGISGGHLNPAVTLGNAVFGKFPWKK 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681  81 VIGYIIAQVVGGIIAAAVLYVV------ASGKAGFDAAASGFASNGYGEHSPGGfSMLSAIVIEIVLTCGFLLVIHGATD 154
Cdd:PTZ00016  128 LPGYFVAQLLGAFVGAACVYGLyygffkDHGIPELPWETMANGFAGVFATYPRE-GNFYAIFSELILTAILLLVILAITD 206

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681 155 KH--APAGFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQ----GGWALQQ----LWLFWVMPIVGGILGGVLYR 224
Cdd:PTZ00016  207 PNncPAFNYLPVAVGLLVFVIGISFGGNTGYALNPARDLGPRLFSailwGSEVFTKdnyyFWVPLVAPFVGAVLGMFLYD 286


                  ...
gi 1320058681 225 TLL 227
Cdd:PTZ00016  287 KFI 289
PLN00026 PLN00026
aquaporin NIP; Provisional
 3-223 7.88e-24

aquaporin NIP; Provisional


Pssm-ID: 177663 [Multi-domain]  Cd Length: 298  Bit Score: 96.47  E-value: 7.88e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681   3 RKLAAECFGTFWLVFGGCGSAVLAAAF--PELGIGFAGVAlafGLTVLTMAYAVGHISGGHFNPAVTLGLWAGGRFPAKE 80
Cdd:PLN00026   72 RKLGAEFVGTFILIFAATAGPIVNQKYdgAETLIGNAACA---GLAVMIVILSTGHISGAHLNPSLTIAFAALRHFPWKH 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681  81 VIGYIIAQVVGGIIAAAVLyvvasgKAGFDAAASGfasngyGEHSPGGfSMLSAIVIEIVLTCGFLLVIHG-ATDKHAPA 159
Cdd:PLN00026  149 VPAYIAAQVSASICASFAL------KGVFHPFMSG------GVTVPSV-STGQAFALEFIITFNLLFVVTAvATDTRAVG 215

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1320058681 160 GFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWalQQLWLFWVMPIVGGILGGVLY 223
Cdd:PLN00026  216 ELAGIAVGATVMLNILVAGPSTGGSMNPVRTLGPAVAAGNY--RAIWIYLVAPTLGALAGAGTY 277
PLN00183 PLN00183
putative aquaporin NIP7; Provisional
 3-226 3.38e-23

putative aquaporin NIP7; Provisional


Pssm-ID: 215092  Cd Length: 274  Bit Score: 94.54  E-value: 3.38e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681   3 RKLAAECFGTFWLVFGGCGsaVLAAAFPELG-IGFAGVALAFGLTVLTMAYAVGHISGGHFNPAVTLGLWAGGRFPAKEV 81
Cdd:PLN00183   46 RMVLAEMVGTFILMFCVCG--IIASTQLSGGeVGLLEYAATAGLTVVVVVFSIGSISGAHVNPSVTIAFATFGHFPWSKV 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681  82 IGYIIAQVVGGIIAAAVLYVVASGKAGFDAAASGFASNgygehspggfsmlSAIVIEIVLTcgFLLVIHGATDKHAPAGF 161
Cdd:PLN00183  124 PLYITAQTVGSVLATYVGVSVYGVKADLMTTKPAQGCS-------------SAFWVEFIAT--FIVMFLAASLTSQPQSL 188

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1320058681 162 APIA---IGLALTLIHLISIPVTNTSVNPARSTAVAIFqgGWALQQLWLFWVMPIVGGILGGVLYRTL 226
Cdd:PLN00183  189 GHLSgfvIGIAIGLAVLITGPVSGGSMNPARSLGPAIV--SWDFKDIWIYITAPTIGAVAGALMFHLL 254
PLN00166 PLN00166
aquaporin TIP2; Provisional
 7-223 1.40e-20

aquaporin TIP2; Provisional


Pssm-ID: 165733  Cd Length: 250  Bit Score: 86.91  E-value: 1.40e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681   7 AECFGTFWLVFGGCGSAVLAAAFPELGI----GFAGVALAFGLTVLTMAYAVGHISGGHFNPAVTLGLWAGGRFPAKEVI 82
Cdd:PLN00166   23 SEFIATLLFVFAGVGSAIAFAKLTSDAAldpaGLVAVAVAHAFALFVGVSIAANISGGHLNPAVTLGLAIGGNITIITGF 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681  83 GYIIAQVVGGIIAAAVLYVVASGKAgfdAAASGFASngygehspgGFSMLSAIVIEIVLTCGFLLVIHGAT---DKHAPA 159
Cdd:PLN00166  103 FYWIAQCLGSIVACLLLVFVTNGES---VPTHGVAA---------GLGAIEGVVMEIVVTFALVYTVYATAadpKKGSLG 170

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1320058681 160 GFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGwaLQQLWLFWVMPIVGGILGGVLY 223
Cdd:PLN00166  171 TIAPIAIGFIVGANILAAGPFSGGSMNPARSFGPAVVSGD--FSQIWIYWVGPLVGGALAGLIY 232
PLN00027 PLN00027
aquaporin TIP; Provisional
 2-226 4.68e-16

aquaporin TIP; Provisional


Pssm-ID: 177664  Cd Length: 252  Bit Score: 74.82  E-value: 4.68e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681   2 FRKLAAECFGTFWLVFGGCGSAVlaaAFPEL---------GIGFAGVALAFGLTVltmAYAVG-HISGGHFNPAVTLGLW 71
Cdd:PLN00027   20 LKAALAEFISTLIFVFAGEGSGM---AFNKLtdngsttpaGLVAAALAHAFALFV---AVSVGaNISGGHVNPAVTFGAF 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681  72 AGGRFPAKEVIGYIIAQVVGGIIAAAVLYVVASGkagfdAAASGFASNgygehspGGFSMLSAIVIEIVLTCGFLLVIHG 151
Cdd:PLN00027   94 IGGNITLLRGILYWIAQLLGSVVACLLLKFSTGG-----LETSAFSLS-------SGVGVWNAFVFEIVMTFGLVYTVYA 161

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1320058681 152 -ATD--KHAPAGFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALQqlWLFWVMPIVGGILGGVLYRTL 226
Cdd:PLN00027  162 tAVDpkKGDLGIIAPIAIGFIVGANILAGGAFDGASMNPAVSFGPAVVSWTWTNH--WVYWAGPLIGGGIAGLVYELI 237
PLN00167 PLN00167
aquaporin TIP5; Provisional
 2-223 1.28e-14

aquaporin TIP5; Provisional


Pssm-ID: 215085  Cd Length: 256  Bit Score: 70.70  E-value: 1.28e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681   2 FRKLAAECFGTFWLVFGGCGSAVL-------AAAFPElgiGFAGVALAFGLTVLTMAYAVGHISGGHFNPAVTLGLWAGG 74
Cdd:PLN00167   22 LRSYLAEFISTFFFVFAAVGSAMSsrklmpdAASDPS---SLLIVAIANAFALSSAVYIAANISGGHVNPAVTFGMAVGG 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320058681  75 RFPAKEVIGYIIAQVVGGIIAAAVLYVVASGKAgfdaaasgFASNGYGEHSPGgfsmLSAIVIEIVLTCGFLLVIHGATD 154
Cdd:PLN00167   99 HISVPTAMFYWISQMLASVMACLFLKVTTVGQH--------VPTYKIAEEMTG----FGASVLEGVLTFGLVYTVYAAGD 166

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1320058681 155 --KHAPAGFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALQQlwLFWVMPIVGGILGGVLY 223
Cdd:PLN00167  167 prRGLLGAIGPLAIGLVAGANVLAAGPFSGGSMNPACAFGSAVVAGSFKNQA--VYWVGPLLGGAVAGLLY 235
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH