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Volume 25;  2024

Research

Genetic prediction of antihyperglycemic drug targets and risk of epilepsy: a mendelian randomisation study
Kaiping Zhou, Huan Yang, Zhihao Xie, Weiping Wang, Zhenzhen Qu
BMC Pharmacol Toxicol. 2024; 25: 1. Published online 2024 Jan 2. doi: 10.1186/s40360-023-00718-2
PMCID:
PMC10763459
Article PDF–2.0M
Prevalence and factors associated with potential drug-drug interactions in prescriptions presented at private pharmacies in Mbarara city, southwestern Uganda
Allan Phillip Lule, Ogwal Basil Delic, Keneth Katunguka, Francis Muwonge, Tadele Mekuriya Yadesa
BMC Pharmacol Toxicol. 2024; 25: 2. Published online 2024 Jan 2. doi: 10.1186/s40360-023-00719-1
PMCID:
PMC10763418
Article PDF–1.0M
Metabolomic analysis of the serum and urine of rats exposed to diazinon, dimethoate, and cypermethrin alone or in combination
Yu-Jie Liang, Ding-Xin Long, Shanshan Wang, Hui-Ping Wang, Yi-Jun Wu
BMC Pharmacol Toxicol. 2024; 25: 3. Published online 2024 Jan 2. doi: 10.1186/s40360-023-00714-6
PMCID:
PMC10763016
Article PDF–1.3M
Prediction of drug–drug interactions between roflumilast and CYP3A4/1A2 perpetrators using a physiologically-based pharmacokinetic (PBPK) approach
Guangwei Jia, Congcong Ren, Hongyan Wang, Caixia Fan
BMC Pharmacol Toxicol. 2024; 25: 4. Published online 2024 Jan 2. doi: 10.1186/s40360-023-00726-2
PMCID:
PMC10762902
Article PDF–2.1M
Sex-biased gene expression and gene-regulatory networks of sex-biased adverse event drug targets and drug metabolism genes
Jennifer L. Fisher, Amanda D. Clark, Emma F. Jones, Brittany N. Lasseigne
BMC Pharmacol Toxicol. 2024; 25: 5. Published online 2024 Jan 2. doi: 10.1186/s40360-023-00727-1
PMCID:
PMC10763002
Article PDF–5.5M
Pharmacokinetics and pharmacodynamics of perfluoropropane after intra-venous bolus injection of perflutren lipid microsphere injection (DEFINITY®) in healthy Chinese volunteers
Pengfei Li, Ping Du, Jun Peng, Zhixia Zhao, Huiling Li, Weiyue Yu, Shumin Wang, Lihong Liu
BMC Pharmacol Toxicol. 2024; 25: 6. Published online 2024 Jan 2. doi: 10.1186/s40360-023-00729-z
PMCID:
PMC10763448
Article PDF–1.3M
Fenofibrate alleviates NAFLD by enhancing the PPARα/PGC-1α signaling pathway coupling mitochondrial function
Xuemei Wang, Jieying Wang, Cao Ying, Yuan Xing, Xuan Su, Ke Men
BMC Pharmacol Toxicol. 2024; 25: 7. Published online 2024 Jan 3. doi: 10.1186/s40360-023-00730-6
PMCID:
PMC10765888
Article PDF–3.1M
Enoxaparin for VTE thromboprophylaxis during inpatient rehabilitation care: assessment of the standard fixed dosing regimen
Amir Haim, Orli Avnery, Deborah Rubin-Asher, Hagay Amir, Kaifa Hashem, Harel Ben Zvi, Motti Ratmansky
BMC Pharmacol Toxicol. 2024; 25: 8. Published online 2024 Jan 10. doi: 10.1186/s40360-023-00728-0
PMCID:
PMC10782744
Article PDF–1.0M
Sustain-release lipid-liquid crystal formulations of pexiganan against Helicobacter pylori infection: in vitro evaluation in C57BL/6 mice
Kiarash Ghazvini, Hossein Kamali, Hadi Farsiani, Masoud Yousefi, Masoud Keikha
BMC Pharmacol Toxicol. 2024; 25: 9. Published online 2024 Jan 11. doi: 10.1186/s40360-024-00731-z
PMCID:
PMC10785446
Article PDF–1.7M
Lipidomics reveals serum lipid metabolism disorders in CTD-induced liver injury
Shan Li, Xiaotong Duan, Yixin Zhang, Cancan Zhao, Ming Yu, Xiaofei Li, Xiaomei Li, Jianyong Zhang
BMC Pharmacol Toxicol. 2024; 25: 10. Published online 2024 Jan 15. doi: 10.1186/s40360-024-00732-y
PMCID:
PMC10790540
Article PDF–3.7M
Informal sale of antibiotics in Guatemalan convenience stores before and after implementation of federal antibiotic dispensing legislation
N. Rojop, P. Moreno, L. Grajeda, J. Romero, L. Reynoso, E. Muñoz, G. H. Palmer, C. Cordón-Rosales, D. R. Call, B. M. Ramay
BMC Pharmacol Toxicol. 2024; 25: 11. Published online 2024 Jan 25. doi: 10.1186/s40360-023-00720-8
PMCID:
PMC10809560
Article PDF–727K
Comparison of three different prophylactic treatments for postoperative nausea and vomiting after total joint arthroplasty under general anesthesia: a randomized clinical trial
Jinwei Xie, Yingcun Cai, Fuxing Pei
BMC Pharmacol Toxicol. 2024; 25: 12. Published online 2024 Jan 30. doi: 10.1186/s40360-024-00735-9
PMCID:
PMC10826087
Article PDF–1.3M
Drug-drug interaction assessment based on a large-scale spontaneous reporting system for hepato- and renal-toxicity, and thrombocytopenia with concomitant low-dose methotrexate and analgesics use
Takeshi Honma, Kenji Onda, Koichi Masuyama
BMC Pharmacol Toxicol. 2024; 25: 13. Published online 2024 Feb 1. doi: 10.1186/s40360-024-00738-6
PMCID:
PMC10832291
Article PDF–1.7M
Role of uranium toxicity and uranium-induced oxidative stress in advancing kidney injury and endothelial inflammation in rats
Yuwei Yang, Chunmei Dai, Xi Chen, Bin Zhang, Xiaohan Li, Wenyu Yang, Jun Wang, Jiafu Feng
BMC Pharmacol Toxicol. 2024; 25: 14. Published online 2024 Feb 2. doi: 10.1186/s40360-024-00734-w
PMCID:
PMC10837886
Article PDF–1.0M
Determination of the median lethal dose of zinc gluconate in mice and safety evaluation
Yong-cai Wang, Xia Yang, Juan Xiao, Su-mei Wei, Ying Su, Xiu-qi Chen, Ting Huang, Qing-wen Shan
BMC Pharmacol Toxicol. 2024; 25: 15. Published online 2024 Feb 5. doi: 10.1186/s40360-024-00736-8
PMCID:
PMC10840281
Article PDF–2.3M
Large variation in anti-factor Xa levels with nadroparin as thromboprophylaxis in COVID-19 and non-COVID-19 critically ill patients
Monique M.R. de Maat, Henk J. van Leeuwen, Lian Roovers, Sabine J.G.M. Ahlers, Jolanda Lambers, Marcel M.C. Hovens
BMC Pharmacol Toxicol. 2024; 25: 16. Published online 2024 Feb 6. doi: 10.1186/s40360-024-00733-x
PMCID:
PMC10848501
Article PDF–1.6M
Safinamide, an inhibitor of monoamine oxidase, modulates the magnitude, gating, and hysteresis of sodium ion current
Te-Yu Hung, Sheng-Nan Wu, Chin-Wei Huang
BMC Pharmacol Toxicol. 2024; 25: 17. Published online 2024 Feb 8. doi: 10.1186/s40360-024-00739-5
PMCID:
PMC10851555
Article PDF–3.2M
New tricks for old drugs- praziquantel ameliorates bleomycin-induced pulmonary fibrosis in mice
Yanjun Zeng, Rui Hu, Wei Ma, Ying Ding, Yi Zhou, Xin Peng, Lixin Feng, Qingmei Cheng, Ziqiang Luo
BMC Pharmacol Toxicol. 2024; 25: 18. Published online 2024 Feb 14. doi: 10.1186/s40360-024-00737-7
PMCID:
PMC10868045
Article PDF–2.7M
The effect of oral supplementation of Paricalcitol on C-reactive protein levels in chronic kidney disease patients: GRADE-assessed systematic review and dose-response meta-analysis of data from randomized controlled trials
Seyyed Mostafa Arabi, Mostafa Shahraki-Jazinaki, Mahla Chambari, Leila Sadat Bahrami, Sara Sabeti, Mohammaed Ibrahim Mohaildeen Gubari, Basil D. Roufogalis, Amirhossein Sahebkar
BMC Pharmacol Toxicol. 2024; 25: 19. Published online 2024 Feb 23. doi: 10.1186/s40360-024-00740-y
PMCID:
PMC10885610
Article PDF–1.4M
Pharmacovigilance study of BCR-ABL1 tyrosine kinase inhibitors: a safety analysis of the FDA adverse event reporting system
Dehua Zhao, Xiaoqing Long, Jisheng Wang
BMC Pharmacol Toxicol. 2024; 25: 20. Published online 2024 Feb 23. doi: 10.1186/s40360-024-00741-x
PMCID:
PMC10885429
Article PDF–1.3M
Preparation and evaluation of transdermal permeation of Huperzine A ethosomes gel in vitro
Jiyu Wu, Renai Xu, Xiaowei Xu, Shiyuan Ye, Aifang Huang
BMC Pharmacol Toxicol. 2024; 25: 21. Published online 2024 Feb 26. doi: 10.1186/s40360-024-00742-w
PMCID:
PMC10898098
Article PDF–463K
Iron overload induced submandibular glands toxicity in gamma irradiated rats with possible mitigation by hesperidin and rutin
Salwa Farid Ahmed, Eman M. F. El-Maghraby, Maha M. Rashad, Dina W. Bashir
BMC Pharmacol Toxicol. 2024; 25: 22. Published online 2024 Feb 27. doi: 10.1186/s40360-024-00744-8
PMCID:
PMC10900593
Article PDF–3.6M
Pharmacokinetics and bioequivalence evaluation of two oral formulations of cotrimoxazole tablets in healthy Chinese volunteers under fasting conditions
Xu Zuo, Xin Zhao, Jinjin Shi, Tiandong Zhang
BMC Pharmacol Toxicol. 2024; 25: 23. Published online 2024 Feb 27. doi: 10.1186/s40360-024-00743-9
PMCID:
PMC10900551
Article PDF–1.0M
Risk of CKD among patients with DM taking diuretics or SGLT2i: a retrospective cohort study in Taiwan
Han-Jie Lin, Pin-Yang Shih, Stella Chin-Shaw Tsai, Wu-Lung Chuang, Tsai-Ling Hsieh, Heng-Jun Lin, Teng-Shun Yu, Fuu-Jen Tsai, Chiu-Ying Chen, Kuang-Hsi Chang
BMC Pharmacol Toxicol. 2024; 25: 24. Published online 2024 Mar 5. doi: 10.1186/s40360-024-00745-7
PMCID:
PMC10913410
Article PDF–1005K
Immuno-oncological effects of standard anticancer agents and commonly used concomitant drugs: an in vitro assessment
Tove Selvin, Malin Berglund, Lena Lenhammar, Magnus Lindskog, Malin Jarvius, Rolf Larsson, Peter Nygren, Mårten Fryknäs, Claes R Andersson
BMC Pharmacol Toxicol. 2024; 25: 25. Published online 2024 Mar 5. doi: 10.1186/s40360-024-00746-6
PMCID:
PMC10913607
Article PDF–2.8M
Dapagliflozin promotes white adipose tissue browning though regulating angiogenesis in high fat induced obese mice
Lin Xiang, Min Liu, Guangda Xiang, Ling Yue, Junxia Zhang, Xiaoli Xu, Jing Dong
BMC Pharmacol Toxicol. 2024; 25: 26. Published online 2024 Mar 19. doi: 10.1186/s40360-024-00747-5
PMCID:
PMC10949628
Article PDF–7.5M
Effects of nicotine on microRNA-124 expression in bile duct ligation-induced liver fibrosis in rats
Khalil Hajiasgharzadeh, Parviz Shahabi, Elham Karimi-Sales, Mohammad Reza Alipour
BMC Pharmacol Toxicol. 2024; 25: 27. Published online 2024 Mar 28. doi: 10.1186/s40360-024-00749-3
PMCID:
PMC10976767
Article PDF–4.8M
Determination of drug-related problems according to PAIR criteria in dialysis patients: a cross-sectional study in tertiary care hospital
Aysel Pehlivanli, Sayeste Akkan Eren, Sule Sengul, Bilgen Basgut, Sehsuvar Erturk, A. Tanju Ozcelikay
BMC Pharmacol Toxicol. 2024; 25: 28. Published online 2024 Apr 18. doi: 10.1186/s40360-024-00754-6
PMCID:
PMC11025200
Article PDF–239K
Treatment for Covid-19 with SARS-CoV-2 neutralizing antibody BRII-196(Ambavirumab) plus BRII-198(Lomisivir): a retrospective cohort study
Qin Yalan, Hao Lingfang, Liu Xisong, Liang Run, Zhang Junjing, Zhang’ An
BMC Pharmacol Toxicol. 2024; 25: 29. Published online 2024 Apr 19. doi: 10.1186/s40360-024-00753-7
PMCID:
PMC11027409
Article PDF–1.2M
Blocking group 2 innate lymphoid cell activation and macrophage M2 polarization: potential therapeutic mechanisms in ovalbumin-induced allergic asthma by calycosin
Chunyan Tian, Qi Liu, Xiaoyu Zhang, Zhuying Li
BMC Pharmacol Toxicol. 2024; 25: 30. Published online 2024 Apr 22. doi: 10.1186/s40360-024-00751-9
PMCID:
PMC11036756
Article PDF–7.5M
Sustained release delivery of favipiravir through statistically optimized, chemically cross-linked, pH-sensitive, swellable hydrogel
Arooj Khan, Muhammad Zaman, Muhammad Ahsan Waqar, Asif Mahmood, Talal Shaheer, Rai Muhammad Sarfraz, Kanwal Shahzadi, Azmat Ali Khan, Amer M. Alanazi, Milton Kumar Kundu, Md Rabiul Islam, Athanasios Alexiou, Marios Papadakis
BMC Pharmacol Toxicol. 2024; 25: 31. Published online 2024 Apr 29. doi: 10.1186/s40360-024-00752-8
PMCID:
PMC11057099
Article PDF–4.8M
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